Ole Miss vs Kentucky Prediction, Odds, Picks, Best Bets for Week 2 2025

College football's Saturday schedule includes the Ole Miss Rebels taking on the Kentucky Wildcats.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Ole Miss vs Kentucky Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Ole Miss: (-345) | Kentucky: (+270)
• Spread: Ole Miss: -8.5 (-115) | Kentucky: +8.5 (-105)
• Total: 50.5 -- Over: (-115) | Under: (-105)

Ole Miss vs Kentucky Betting Trends

• Ole Miss hasn't lost a game against the spread this season.
• Ole Miss has yet to lose ATS (1-0) as an 8.5-point favorite or greater this year.
• Ole Miss has had one game (of one) hit the over this year.
• Kentucky is winless against the spread this season.
• No Kentucky game has hit the over this season.

Ole Miss vs Kentucky Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Rebels win (85%)

Ole Miss vs Kentucky Point Spread

Ole Miss is favored by 8.5 points over Kentucky. Ole Miss is -115 to cover the spread, with Kentucky being -105.

Ole Miss vs Kentucky Over/Under

An over/under of 50.5 has been set for Ole Miss-Kentucky on Sept. 6, with the over being -115 and the under -105.

Ole Miss vs Kentucky Moneyline

Ole Miss is the favorite, -345 on the moneyline, while Kentucky is a +270 underdog.

Ole Miss vs. Kentucky Points Insights

• The Rebels' average implied point total last season was 9.2 more points than their implied total in Saturday's game (39.2 implied points on average compared to 30 implied points in this game).
• The average implied point total last season for the Wildcats (31.3) is 10.3 more points than the team's implied total in this matchup (21).

Ole Miss vs. Kentucky Game Info

• Game day: Saturday, September 6, 2025
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Lexington, Kentucky
• Stadium: Kroger Field

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