Notre Dame vs USC Prediction, Odds, & Betting Trends for College Football Week 7 Game

The Notre Dame Fighting Irish will face the USC Trojans in college football action on Saturday.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

Notre Dame vs USC Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Notre Dame: (-156) | USC: (+130)
• Spread: Notre Dame: -3 (-108) | USC: +3 (-112)
• Total: 60.5 -- Over: (-108) | Under: (-112)

Notre Dame vs USC Betting Trends

• Notre Dame's record against the spread is 5-2-0.
• On the season, Notre Dame is 4-2 as 3-point or better favorites.
• Notre Dame has played seven games this year, and three of them have hit the over.
• USC has won twice against the spread this year.
• There have been five USC games (out of six) that hit the over this year.

Notre Dame vs USC Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Fighting Irish win (67.8%)

Notre Dame vs USC Point Spread

USC is the underdog by three points against Notre Dame. USC is -108 to cover the spread, and Notre Dame is -112.

Notre Dame vs USC Over/Under

The over/under for Notre Dame-USC on October 14 is 60.5. The over is -108, and the under is -112.

Notre Dame vs USC Moneyline

Notre Dame is the favorite, -156 on the moneyline, while USC is a +130 underdog.

Notre Dame vs. USC Points Insights

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Check out even more in-depth Notre Dame vs. USC analysis on FanDuel Research.