Sunday’s MLB Strikeout Props - Sept. 21

Will Tyler Glasnow strike out more than 7.5 batters? Can Michael Wacha surpass 2.5 strikeouts? See their odds and more strikeout prop odds for all pitchers in MLB play on Sept. 21, in the article below.

Today's MLB Strikeout Props

Seattle Mariners at Houston Astros

• Jason Alexander (Astros): Over/Under 4.5 Ks (Over +114, Under -152) | 2025 Stats: 3.8 strikeouts per game in 16 appearances
• Logan Gilbert (Mariners): Over/Under 6.5 Ks (Over -102, Under -130) | 2025 Stats: 7.1 strikeouts per game in 23 appearances

Athletics at Pittsburgh Pirates

• Mike Burrows (Pirates): Over/Under 4.5 Ks (Over +112, Under -148) | 2025 Stats: 4.5 strikeouts per game in 21 appearances
• Mitch Spence (Athletics): Over/Under 3.5 Ks (Over -128, Under -104) | 2025 Stats: 2.1 strikeouts per game in 30 appearances

Milwaukee Brewers at St. Louis Cardinals

• Matthew Liberatore (Cardinals): Over/Under 3.5 Ks (Over +102, Under -138) | 2025 Stats: 4.1 strikeouts per game in 28 appearances

Toronto Blue Jays at Kansas City Royals

• Trey Yesavage (Blue Jays): Over/Under 4.5 Ks (Over -132, Under +102) | 2025 Stats: 9 strikeouts per game in 1 appearance
• Michael Wacha (Royals): Over/Under 2.5 Ks (Over -158, Under +118) | 2025 Stats: 4 strikeouts per game in 29 appearances

Los Angeles Angels at Colorado Rockies

• Kyle Hendricks (Angels): Over/Under 2.5 Ks (Over -158, Under +118) | 2025 Stats: 3.5 strikeouts per game in 30 appearances
• German Marquez (Rockies): Over/Under 4.5 Ks (Over +100, Under -132) | 2025 Stats: 3.3 strikeouts per game in 25 appearances
• Kyle Freeland (Rockies): Over/Under 4.5 Ks (Over +110, Under -152) | 2025 Stats: 3.9 strikeouts per game in 29 appearances
• Caden Dana (Angels): Over/Under 4.5 Ks (Over +108, Under -148) | 2025 Stats: 4.6 strikeouts per game in 5 appearances

New York Yankees at Baltimore Orioles

• Cam Schlittler (Yankees): Over/Under 6.5 Ks (Over +116, Under -154) | 2025 Stats: 5.8 strikeouts per game in 12 appearances
• Kyle Bradish (Orioles): Over/Under 5.5 Ks (Over -154, Under +116) | 2025 Stats: 7.5 strikeouts per game in 4 appearances

Atlanta Braves at Detroit Tigers

• Spencer Strider (Braves): Over/Under 6.5 Ks (Over +106, Under -140) | 2025 Stats: 5.7 strikeouts per game in 21 appearances
• Casey Mize (Tigers): Over/Under 4.5 Ks (Over +112, Under -148) | 2025 Stats: 4.8 strikeouts per game in 26 appearances

Cleveland Guardians at Minnesota Twins

• Joey Cantillo (Guardians): Over/Under 5.5 Ks (Over -120, Under -110) | 2025 Stats: 3 strikeouts per game in 32 appearances
• Simeon Woods Richardson (Twins): Over/Under 4.5 Ks (Over -136, Under +102) | 2025 Stats: 4.5 strikeouts per game in 21 appearances

San Diego Padres at Chicago White Sox

• Sean Burke (White Sox): Over/Under 3.5 Ks (Over -140, Under +106) | 2025 Stats: 4.6 strikeouts per game in 26 appearances
• Michael King (Padres): Over/Under 5.5 Ks (Over +114, Under -152) | 2025 Stats: 5.3 strikeouts per game in 13 appearances

Miami Marlins at Texas Rangers

• Eury Pérez (Marlins): Over/Under 5.5 Ks (Over +126, Under -168) | 2025 Stats: 4.7 strikeouts per game in 18 appearances

Philadelphia Phillies at Arizona Diamondbacks

• Zac Gallen (Diamondbacks): Over/Under 5.5 Ks (Over +118, Under -158) | 2025 Stats: 5.4 strikeouts per game in 32 appearances
• Ranger Suarez (Phillies): Over/Under 4.5 Ks (Over -102, Under -130) | 2025 Stats: 6 strikeouts per game in 24 appearances
• Aaron Nola (Phillies): Over/Under 5.5 Ks (Over +118, Under -158) | 2025 Stats: 5.5 strikeouts per game in 16 appearances
• Eduardo Rodríguez (Diamondbacks): Over/Under 5.5 Ks (Over +126, Under -166) | 2025 Stats: 4.9 strikeouts per game in 27 appearances

San Francisco Giants at Los Angeles Dodgers

• Tyler Glasnow (Dodgers): Over/Under 7.5 Ks (Over +100, Under -132) | 2025 Stats: 6.1 strikeouts per game in 17 appearances
• Emmet Sheehan (Dodgers): Over/Under 6.5 Ks (Over +108, Under -144) | 2025 Stats: 5.8 strikeouts per game in 13 appearances
• Kai-Wei Teng (Giants): Over/Under 4.5 Ks (Over +114, Under -152) | 2025 Stats: 4.9 strikeouts per game in 8 appearances

Chicago Cubs at Cincinnati Reds

• Andrew Abbott (Reds): Over/Under 4.5 Ks (Over -104, Under -130) | 2025 Stats: 5.3 strikeouts per game in 27 appearances
• Jameson Taillon (Cubs): Over/Under 4.5 Ks (Over +108, Under -144) | 2025 Stats: 4.1 strikeouts per game in 21 appearances

Washington Nationals at New York Mets

• Jake Irvin (Nationals): Over/Under 3.5 Ks (Over +108, Under -144) | 2025 Stats: 3.6 strikeouts per game in 31 appearances
• Sean Manaea (Mets): Over/Under 5.5 Ks (Over -108, Under -120) | 2025 Stats: 5.7 strikeouts per game in 12 appearances