Sunday’s MLB Odds, Betting Lines and Predictions - Sept. 21

Today's MLB schedule has several top-tier games, including a matchup between the Boston Red Sox and the Tampa Bay Rays. Below, we have predictions for every game.

Today's MLB Odds and Predictions

Atlanta Braves at Detroit Tigers Odds, Lines & Predictions

Game Info

• When: 1:10 p.m. ET
• Where: Comerica Park
• TV Channel: FDSDET and FDSSO
• Probable Pitchers: Casey Mize vs. Spencer Strider
• Records: Tigers (85-71), Braves (73-83)
• Tigers Moneyline Odds: -120
• Braves Moneyline Odds: +102

numberFire Prediction

• numberFire Predicted Favorite: Tigers
• Tigers Win Probability: 57.47%
• Braves Win Probability: 42.53%

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Athletics at Pittsburgh Pirates Odds, Lines & Predictions

Game Info

• When: 1:35 p.m. ET
• Where: PNC Park
• TV Channel: SportsNet PT and NBCS-CA
• Probable Pitchers: Mike Burrows vs. Mitch Spence
• Records: Pirates (67-89), Athletics (73-83)
• Pirates Moneyline Odds: -118
• Athletics Moneyline Odds: +100

numberFire Prediction

• numberFire Predicted Favorite: Pirates
• Pirates Win Probability: 53.57%
• Athletics Win Probability: 46.43%

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New York Yankees at Baltimore Orioles Odds, Lines & Predictions

Game Info

• When: 1:35 p.m. ET
• Where: Oriole Park at Camden Yards
• TV Channel: MASN and YES
• Probable Pitchers: Kyle Bradish vs. Cam Schlittler
• Records: Orioles (73-83), Yankees (88-68)
• Yankees Moneyline Odds: -134
• Orioles Moneyline Odds: +114

numberFire Prediction

• numberFire Predicted Favorite: Orioles
• Orioles Win Probability: 52.01%
• Yankees Win Probability: 47.99%

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Chicago Cubs at Cincinnati Reds Odds, Lines & Predictions

Game Info

• When: 1:40 p.m. ET
• Where: Great American Ball Park
• TV Channel: MLB Network, FDSOH and MARQ+
• Probable Pitchers: Andrew Abbott vs. Jameson Taillon
• Records: Reds (80-76), Cubs (88-68)
• Reds Moneyline Odds: -124
• Cubs Moneyline Odds: +106

numberFire Prediction

• numberFire Predicted Favorite: Reds
• Reds Win Probability: 50.64%
• Cubs Win Probability: 49.36%

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Washington Nationals at New York Mets Odds, Lines & Predictions

Game Info

• When: 1:40 p.m. ET
• Where: Citi Field
• TV Channel: WPIX and MASN2
• Probable Pitchers: Sean Manaea vs. Jake Irvin
• Records: Mets (80-76), Nationals (64-92)
• Mets Moneyline Odds: -275
• Nationals Moneyline Odds: +225

numberFire Prediction

• numberFire Predicted Favorite: Mets
• Mets Win Probability: 74.01%
• Nationals Win Probability: 25.99%

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Cleveland Guardians at Minnesota Twins Odds, Lines & Predictions

Game Info

• When: 2:10 p.m. ET
• Where: Target Field
• TV Channel: MNNT and CLEG
• Probable Pitchers: Simeon Woods Richardson vs. Joey Cantillo
• Records: Twins (67-89), Guardians (84-72)
• Guardians Moneyline Odds: -142
• Twins Moneyline Odds: +120

numberFire Prediction

• numberFire Predicted Favorite: Twins
• Twins Win Probability: 56.07%
• Guardians Win Probability: 43.93%

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Toronto Blue Jays at Kansas City Royals Odds, Lines & Predictions

Game Info

• When: 2:10 p.m. ET
• Where: Kauffman Stadium
• TV Channel: FDSKC and SNET
• Probable Pitchers: Michael Wacha vs. Trey Yesavage
• Records: Royals (78-78), Blue Jays (90-66)
• Blue Jays Moneyline Odds: -124
• Royals Moneyline Odds: +106

numberFire Prediction

• numberFire Predicted Favorite: Blue Jays
• Blue Jays Win Probability: 50.18%
• Royals Win Probability: 49.82%

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San Diego Padres at Chicago White Sox Odds, Lines & Predictions

Game Info

• When: 2:10 p.m. ET
• Where: Rate Field
• TV Channel: CHSN and SDPA
• Probable Pitchers: Sean Burke vs. Michael King
• Records: White Sox (58-98), Padres (85-71)
• Padres Moneyline Odds: -180
• White Sox Moneyline Odds: +152

numberFire Prediction

• numberFire Predicted Favorite: Padres
• Padres Win Probability: 63.64%
• White Sox Win Probability: 36.36%

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Milwaukee Brewers at St. Louis Cardinals Odds, Lines & Predictions

Game Info

• When: 2:15 p.m. ET
• Where: Busch Stadium
• TV Channel: FDSMW and FDSWI
• Probable Pitchers: Matthew Liberatore vs. Robert Gasser
• Records: Cardinals (76-80), Brewers (95-61)
• Brewers Moneyline Odds: -130
• Cardinals Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Brewers
• Brewers Win Probability: 53.21%
• Cardinals Win Probability: 46.79%

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Miami Marlins at Texas Rangers Odds, Lines & Predictions

Game Info

• When: 2:35 p.m. ET
• Where: Globe Life Field
• TV Channel: RSN and FDSFL
• Probable Pitchers: Merrill Kelly vs. Eury Pérez
• Records: Rangers (79-77), Marlins (76-80)
• Rangers Moneyline Odds: -126
• Marlins Moneyline Odds: +108

numberFire Prediction

• numberFire Predicted Favorite: Rangers
• Rangers Win Probability: 57.00%
• Marlins Win Probability: 43.00%

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Los Angeles Angels at Colorado Rockies Odds, Lines & Predictions

Game Info

• When: 3:10 p.m. ET
• Where: Coors Field
• TV Channel: COLR and FDSW
• Probable Pitchers: Kyle Freeland vs. Caden Dana
• Records: Rockies (43-113), Angels (70-86)
• Rockies Moneyline Odds: -112
• Angels Moneyline Odds: -104

numberFire Prediction

• numberFire Predicted Favorite: Rockies
• Rockies Win Probability: 55.07%
• Angels Win Probability: 44.93%

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Philadelphia Phillies at Arizona Diamondbacks Odds, Lines & Predictions

Game Info

• When: 4:10 p.m. ET
• Where: Chase Field
• TV Channel: ARID and NBCS-PH
• Probable Pitchers: Eduardo Rodríguez vs. Ranger Suarez
• Records: Diamondbacks (78-77), Phillies (92-63)
• Phillies Moneyline Odds: -130
• Diamondbacks Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Phillies
• Phillies Win Probability: 59.18%
• Diamondbacks Win Probability: 40.82%

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San Francisco Giants at Los Angeles Dodgers Odds, Lines & Predictions

Game Info

• When: 4:10 p.m. ET
• Where: Dodger Stadium
• TV Channel: SportsNet LA and NBCS-BA
• Probable Pitchers: Emmet Sheehan vs. Trevor McDonald
• Records: Dodgers (88-67), Giants (76-79)
• Dodgers Moneyline Odds: -220
• Giants Moneyline Odds: +184

numberFire Prediction

• numberFire Predicted Favorite: Dodgers
• Dodgers Win Probability: 64.56%
• Giants Win Probability: 35.44%

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Seattle Mariners at Houston Astros Odds, Lines & Predictions

Game Info

• When: 7:10 p.m. ET
• Where: Daikin Park
• TV Channel: ESPN
• Probable Pitchers: Jason Alexander vs. Logan Gilbert
• Records: Astros (84-71), Mariners (86-69)
• Mariners Moneyline Odds: -148
• Astros Moneyline Odds: +126

numberFire Prediction

• numberFire Predicted Favorite: Mariners
• Mariners Win Probability: 58.56%
• Astros Win Probability: 41.44%

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Boston Red Sox at Tampa Bay Rays Odds, Lines & Predictions

Game Info

• When: 7:35 p.m. ET
• Where: George M. Steinbrenner Field
• TV Channel: FDSSUN and NESN
• Probable Pitchers: Joe Boyle vs. Connelly Early
• Records: Rays (75-80), Red Sox (85-70)
• Red Sox Moneyline Odds: -130
• Rays Moneyline Odds: +110

numberFire Prediction

• numberFire Predicted Favorite: Rays
• Rays Win Probability: 51.63%
• Red Sox Win Probability: 48.37%

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All MLB win probability predictions and picks are according to numberFire.