Angels vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 21

Odds updated as of 2:12 p.m.

The Los Angeles Angels will face the Colorado Rockies in MLB action on Sunday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

Angels vs Rockies Game Info

• Los Angeles Angels (70-85) vs. Colorado Rockies (42-113)
• Date: Sunday, September 21, 2025
• Time: 3:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSW

Angels vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-124) | COL: (+106)
• Spread: LAA: -1.5 (+118) | COL: +1.5 (-142)
• Total: 11.5 -- Over: (-118) | Under: (-104)

Angels vs Rockies Probable Starting Pitchers

Probable Pitchers: Caden Dana (Angels) - 0-2, 7.45 ERA vs Kyle Freeland (Rockies) - 4-16, 5.14 ERA

This contest's pitching matchup is set, as the Angels will send Caden Dana (0-2) to the mound, while Kyle Freeland (4-16) will get the nod for the Rockies. Dana's team is 1-2-0 against the spread in his starts this season. Dana's team lost his only start as a favorite this season. The Rockies are 12-16-0 ATS in Freeland's 28 starts that had a set spread. The Rockies are 7-20 in Freeland's 27 starts this season that they were the moneyline underdog.

Angels vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rockies win (55.1%)

Angels vs Rockies Moneyline

• The Angels vs Rockies moneyline has Los Angeles as a -124 favorite, while Colorado is a +106 underdog at home.

Angels vs Rockies Spread

• The Rockies are hosting the Angels, and are +1.5 on the runline. The Rockies are +118 to cover the spread, and the Angels are -142.

Angels vs Rockies Over/Under

• A total of 11.5 runs has been set for the Angels-Rockies contest on Sept. 21, with the over available at -118 and the under at -104.

Bet on Los Angeles Angels vs. Colorado Rockies on FanDuel today!

Angels vs Rockies Betting Trends

• The Angels have been favorites in 36 games this season and have come away with the win 18 times (50%) in those contests.
• This season Los Angeles has been victorious 14 times in 27 chances when named as a favorite of at least -124 on the moneyline.
• Contests with the Angels have gone over the total set by oddsmakers in 82 of 153 chances this season.
• In 153 games with a line this season, the Angels have a mark of 81-72-0 against the spread.
• The Rockies have been the underdog on the moneyline 146 total times this season. They've finished 38-108 in those games.
• Colorado has a record of 35-105 in games it has played as a moneyline underdog with odds of +106 or longer (25%).
• In the 150 games bookmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 66 times (66-79-5).
• The Rockies have a 60-90-0 record against the spread this season.

Angels Player Leaders

• Taylor Ward is batting .228 with 31 doubles, two triples, 34 home runs and 72 walks. He has an on-base percentage of .316 while slugging .472.
• He is 137th in batting average, 101st in on-base percentage, and 38th in slugging among qualifying hitters in baseball.
• Ward has recorded a base hit in four straight games. In his last five games he is batting .368 with three home runs and three RBIs.
• Jo Adell leads Los Angeles in total hits (118) this season while batting .236 with 54 extra-base hits. He's slugging .491 with an on-base percentage of .295.
• He ranks 121st in batting average, 125th in on-base percentage and 20th in slugging in the majors.
• Nolan Schanuel has collected 126 base hits, an OBP of .355 and a slugging percentage of .391 this season.
• Schanuel has picked up a hit in two straight games. In his last five games he is hitting .167 with a double, a home run and three RBIs.
• Mike Trout leads Los Angeles with an OBP of .358 this season while batting .229 with 85 walks and 67 runs scored.

Rockies Player Leaders

• Hunter Goodman has put up a team-best OBP (.327) and slugging percentage (.527), while pacing the Rockies in hits (144, while batting .281).
• Including all the qualifying players in the big leagues, his batting average puts him 23rd, his on-base percentage ranks 77th, and he is 11th in slugging.
• Goodman hopes to build on a five-game hitting streak in this matchup. During his last five outings he is batting .381 with a double, a triple, two walks and an RBI.
• Mickey Moniak is batting .272 with 18 doubles, eight triples, 24 home runs and 21 walks. He's slugging .525 with an on-base percentage of .308.
• Jordan Beck a has .327 on-base percentage to pace the Rockies.
• Tyler Freeman has 20 doubles, two triples, two home runs and 34 walks while batting .281.

Angels vs Rockies Head to Head

• 9/20/2025: 3-0 LAA (Favorite: Angels, Spread: -1.5, Total: 11.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2025: 7-6 COL (Favorite: Angels, Spread: -1.5, Total: 11.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/1/2024: 5-4 COL (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/31/2024: 2-1 COL (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/30/2024: 10-7 LAA (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/25/2023: 4-3 COL (Favorite: Angels, Spread: -1.5, Total: 12.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/24/2023: 25-1 LAA (Favorite: Angels, Spread: -1.5, Total: 12.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/23/2023: 7-4 COL (Favorite: Angels, Spread: -1.5, Total: 12, Favorite Moneyline: -156, Underdog Moneyline: +132)

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