Missouri vs Mississippi State Prediction, Odds, Picks, Best Bets for Week 12 2025

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The Saturday schedule in college football includes a matchup between the Missouri Tigers and the Mississippi State Bulldogs.

We've got you covered, in terms of the vital information regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Missouri vs Mississippi State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Missouri: (-255) | Mississippi State: (+210)
Spread: Missouri: -6.5 (-122) | Mississippi State: +6.5 (100)
Total: 51.5 -- Over: (-110) | Under: (-110)

Missouri has covered the spread five times in nine games.
As at least a 6.5-point favorite, Missouri has two wins ATS (2-2).
Out of nine Missouri games so far this year, five have hit the over.
Mississippi State has covered the spread eight times in 10 games.
Mississippi State has an ATS record of 4-2 as 6.5-point underdogs or more.
This season, five of Mississippi State's 10 games have gone over the point total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (71.8%)

Mississippi State is a 6.5-point underdog against Missouri. Mississippi State is +100 to cover the spread, and Missouri is -122.

Missouri versus Mississippi State on Nov. 15 has an over/under of 51.5 points, with the over -110 and the under -110.

The Missouri vs Mississippi State moneyline has Missouri as a -255 favorite, while Mississippi State is a +210 underdog.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Total Games
Missouri	33.3	38	19.1	20	50.3	9
Mississippi State	32.0	23	26.3	92	56.6	10

Check out even more in-depth Missouri vs. Mississippi State analysis on FanDuel Research.

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