Missouri vs Louisiana Prediction, Odds, Picks, Best Bets for Week 3 2025

In college football action on Saturday, the Missouri Tigers take on the Louisiana Ragin' Cajuns.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Missouri vs Louisiana Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Missouri: (-7143) | Louisiana: (+2000)
• Spread: Missouri: -27.5 (-105) | Louisiana: +27.5 (-115)
• Total: 47.5 -- Over: (-110) | Under: (-110)

Missouri vs Louisiana Betting Trends

• Missouri is unbeaten against the spread this season.
• Missouri is unbeaten ATS (1-0) as a 27.5-point favorite or greater this season.
• Every Missouri game has hit the over this season.
• Louisiana has not won a game against the spread this year.
• No Louisiana game has gone over the point total this season.

Missouri vs Louisiana Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (86.2%)

Missouri vs Louisiana Point Spread

Missouri is favored by 27.5 points over Louisiana. Missouri is -105 to cover the spread, with Louisiana being -115.

Missouri vs Louisiana Over/Under

An over/under of 47.5 has been set for Missouri-Louisiana on Sept. 13, with the over being -110 and the under -110.

Missouri vs Louisiana Moneyline

Missouri is the favorite, -7143 on the moneyline, while Louisiana is a +2000 underdog.

Missouri vs. Louisiana Points Insights

Missouri vs. Louisiana Game Info

• Game day: Saturday, September 13, 2025
• Game time: 1 p.m. ET
• TV channel: SEC Network+
• Location: Columbia, Missouri
• Stadium: Memorial Stadium/Faurot Field

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Check out even more in-depth Missouri vs. Louisiana analysis on FanDuel Research.