Marlins vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 5:16 a.m.

The MLB's Wednesday schedule includes the Miami Marlins taking on the Colorado Rockies.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Marlins vs Rockies Game Info

• Miami Marlins (71-80) vs. Colorado Rockies (41-110)
• Date: Wednesday, September 17, 2025
• Time: 8:40 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: COLR and FDSFL

Marlins vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-164) | COL: (+138)
• Spread: MIA: -1.5 (-110) | COL: +1.5 (-110)
• Total: 10.5 -- Over: (-122) | Under: (-100)

Marlins vs Rockies Probable Starting Pitchers

Probable Pitchers: Ryan Weathers (Marlins) - 2-1, 2.73 ERA vs McCade Brown (Rockies) - 0-4, 9.88 ERA

The Marlins will give the ball to Ryan Weathers (2-1, 2.73 ERA), who is eyeing win No. 3 on the season, and the Rockies will turn to McCade Brown (0-4, 9.88 ERA). When Weathers starts, his team is 4-2-0 against the spread this season. Weathers' team won his only start as a favorite this season. The Rockies have a 1-3-0 record against the spread in Brown's starts. The Rockies were the moneyline underdog for four Brown starts this season -- they lost every time.

Marlins vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (60%)

Marlins vs Rockies Moneyline

• Miami is a -164 favorite on the moneyline, while Colorado is a +138 underdog at home.

Marlins vs Rockies Spread

• The Rockies are +1.5 on the run line against the Marlins. The Rockies are -110 to cover, and the Marlins are -110.

Marlins vs Rockies Over/Under

• The over/under for the Marlins versus Rockies game on Sept. 17 has been set at 10.5, with -122 odds on the over and -100 odds on the under.

Bet on Miami Marlins vs. Colorado Rockies on FanDuel today!

Marlins vs Rockies Betting Trends

• The Marlins have won in 11, or 42.3%, of the 26 contests they have been named as odds-on favorites in this year.
• Miami has been listed as a favorite of -164 or more on two occasions this season and lost both games.
• Contests with the Marlins have gone over the total set by bookmakers in 73 of 147 chances this season.
• The Marlins are 83-64-0 against the spread in their 147 games with a line set by sportsbooks this season.
• The Rockies have put together a 37-106 record in games they were the underdog on the moneyline (winning 25.9% of those games).
• In games it has played as a moneyline underdog with odds of +138 or longer, Colorado has a 30-91 record (winning just 24.8% of its games).
• The Rockies have played in 147 games with a set over/under, and have combined with opponents to go over the total 64 times (64-78-5).
• The Rockies are 59-88-0 ATS this season.

Marlins Player Leaders

• Otto Lopez is batting .248 with 18 doubles, 14 home runs and 44 walks. He has an on-base percentage of .311 while slugging .369.
• Among qualifying hitters in MLB, his batting average ranks 95th, his on-base percentage ranks 106th, and he is 133rd in slugging.
• Xavier Edwards is slashing .280/.339/.353 this season and leads the Marlins with an OPS of .692.
• His batting average is 23rd among qualified players, his on-base percentage 53rd, and his slugging percentage 142nd.
• Agustin Ramirez has 114 hits and is batting .230 this season.
• Ramirez heads into this game with seven games in a row with at least one hit. During his last 10 games he is hitting .263 with a double, a home run, three walks and three RBIs.
• Eric Wagaman has been key for Miami with 113 hits, an OBP of .299 plus a slugging percentage of .384.
• Wagaman takes a five-game hitting streak into this game. During his last five outings he is hitting .556 with two doubles and four RBIs.

Rockies Player Leaders

• Hunter Goodman has put up a slugging percentage of .524 and has 137 hits, both team-best numbers for the Rockies. He's batting .276 and with an on-base percentage of .321.
• He ranks 31st in batting average, 92nd in on-base percentage and 10th in slugging percentage among all qualifying batters in MLB.
• Mickey Moniak has 17 doubles, eight triples, 22 home runs and 21 walks while batting .270. He's slugging .515 with an on-base percentage of .307.
• Jordan Beck a has .330 on-base percentage to lead the Rockies.
• Tyler Freeman is hitting .279 with 19 doubles, two triples, two home runs and 34 walks.

Marlins vs Rockies Head to Head

• 9/16/2025: 6-5 MIA (Favorite: Marlins, Spread: -1.5, Total: 10, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/4/2025: 3-2 COL (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/3/2025: 3-2 COL (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/2/2025: 6-4 COL (Favorite: Marlins, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 8/29/2024: 12-8 MIA (Favorite: Rockies, Spread: -1.5, Total: 11.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/28/2024: 8-2 COL (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/27/2024: 9-8 MIA (Favorite: Rockies, Spread: -1.5, Total: 11, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/26/2024: 3-2 COL (Favorite: Rockies, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/2/2024: 5-4 MIA (Favorite: Marlins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/1/2024: 4-1 MIA (Favorite: Marlins, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)

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