Marlins vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for May 5

Odds updated as of 2:11 a.m.

The Miami Marlins versus the Baltimore Orioles is on the MLB schedule for Tuesday.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Marlins vs Orioles Game Info

• Miami Marlins (16-19) vs. Baltimore Orioles (15-20)
• Date: Tuesday, May 5, 2026
• Time: 6:40 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: Marlins.TV and MASN

Marlins vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-118) | BAL: (+100)
• Spread: MIA: +1.5 (-205) | BAL: -1.5 (+168)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Marlins vs Orioles Probable Starting Pitchers

Probable Pitchers: Sandy Alcantara (Marlins) - 3-2, 3.04 ERA vs Chris Bassitt (Orioles) - 2-2, 5.46 ERA

The Marlins will give the nod to Sandy Alcantara (3-2) against the Orioles and Chris Bassitt (2-2). Alcantara's team is 3-4-0 against the spread in his starts this season. Alcantara's team is 3-2 this season when he starts and they are the moneyline favorite. The Orioles have gone 4-2-0 ATS in Bassitt's six starts with a set spread. The Orioles are 3-1 in Bassitt's four starts this season that they were the moneyline underdog.

Marlins vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (61.3%)

Marlins vs Orioles Moneyline

• Baltimore is the underdog, +100 on the moneyline, while Miami is a -118 favorite at home.

Marlins vs Orioles Spread

• The Orioles are 1.5-run favorites against the spread for this matchup with the Marlins. The Orioles are +168 to cover, while the Marlins are -205 to cover as a 1.5-run underdog on the runline.

Marlins vs Orioles Over/Under

• A combined run total of 8.5 has been set for Marlins-Orioles on May 5, with the over at -110 and the under at -110.

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Marlins vs Orioles Betting Trends

• The Marlins have been victorious in 12, or 66.7%, of the 18 contests they have been chosen as favorites in this season.
• This season Miami has been victorious 10 times in 13 chances when named as a favorite of at least -118 on the moneyline.
• The Marlins' games have gone over the total in 19 of their 34 opportunities.
• The Marlins have posted a record of 16-18-0 against the spread this season.
• The Orioles have won 21.4% of the games this season they were the underdog on the moneyline (3-11).
• Baltimore has gone 3-9 in games it has played as a moneyline underdog with odds of +100 or longer (25%).
• The Orioles have had an over/under set by bookmakers 35 times, and have combined with opponents to go over the total in 24 of those games (24-11-0).
• The Orioles have collected a 14-21-0 record ATS this season (covering 40% of the time).

Marlins Player Leaders

• Xavier Edwards leads Miami in OBP (.419) this season, fueled by 43 hits. He has a .333 batting average and a slugging percentage of .465.
• Among all qualifying batters in the majors, he ranks fifth in batting average, sixth in on-base percentage, and 45th in slugging.
• Edwards hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .343 with two doubles, a home run, six walks and four RBIs.
• Liam Hicks leads Miami with 30 hits. He is batting .297 this season and has 10 extra-base hits. He's also slugging .535 with an on-base percentage of .353.
• His batting average ranks 30th among qualified players, his on-base percentage 62nd, and his slugging percentage 16th.
• Otto Lopez has hit three homers with a team-high .493 SLG this season.
• Lopez has logged a hit or more in seven straight games. During his last 10 outings he is batting .386 with three doubles and four RBIs.
• Jakob Marsee has one home run, eight RBI and a batting average of .185 this season.

Orioles Player Leaders

• Taylor Ward has put up an on-base percentage of .423 and a slugging percentage of .416. Both lead the Orioles. He's batting .288.
• He is 37th in batting average, fourth in on-base percentage and 77th in slugging percentage among all qualified batters in the big leagues.
• Gunnar Henderson paces his team with 30 hits. He has a batting average of .208 while slugging .451 with an on-base percentage of .272.
• Including all qualified hitters, he is 153rd in batting average, 156th in on-base percentage and 52nd in slugging percentage.
• Pete Alonso has eight doubles, six home runs and 19 walks while hitting .215.
• Jeremiah Jackson is hitting .259 with three doubles, six home runs and two walks.

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