Louisville vs South Carolina State College Basketball Prediction, Odds, Picks, Best Bets for Nov. 3

The Louisville Cardinals hit the court against the South Carolina State Bulldogs on November 3, 2025 ET in the first game of the 2025-26 season for both teams.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Louisville vs. South Carolina State Game Info and Odds

• Game day: Monday, November 3, 2025
• Game time: 9 p.m. ET
• TV channel: ACC Network
• Location: Louisville, Kentucky
• Arena: KFC Yum! Center

Take a look at some betting trends for Louisville (-35.5) versus South Carolina State on Monday. The over/under has been set at 158.5 points for this game.

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Louisville vs. South Carolina State: ATS Betting Stats and Trends

• Louisville won 20 games against the spread last season, while failing to cover 15 times.
• South Carolina State compiled a 21-9-0 record against the spread last season.
• The Cardinals sported a worse record against the spread when playing at home (8-9-0) than they did on the road (9-2-0) last season.
• Last year, the Bulldogs were 8-1-0 at home against the spread (.889 winning percentage). On the road, they were 10-7-0 ATS (.588).

Louisville vs. South Carolina State Head-to-Head Comparison

• Last year, Louisville was 65th in the nation on offense (78.5 points scored per game) and 89th defensively (69.5 points conceded).
• Louisville was 47th in the country in rebounds per game (34.6) and 114th in rebounds conceded (30.2) last season.
• Louisville was 148th in the country in assists (13.9 per game) last year.
• Last season, Louisville was 150th in the nation in turnovers committed (10.9 per game) and 93rd in turnovers forced (12.2).
• South Carolina State was 47th in college basketball last season with 79.5 points per game. At the other end, it ranked 126th with 70.4 points allowed per contest.
• Last year South Carolina State pulled down 32 boards per game (179th-ranked in college basketball) and allowed 28.1 rebounds per contest (27th-ranked).
• Last season South Carolina State ranked 57th in college basketball in assists, averaging 15.6 per game.
• South Carolina State struggled in terms of turnovers last year, ranking 17th-worst in the nation with 13.5 turnovers per game. On the other hand, it ranked third-best in college basketball with 15.7 forced turnovers per game.

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