Kansas vs West Virginia Prediction, Odds, Picks, Best Bets for Week 4 2025

The college football schedule on Saturday includes the Kansas Jayhawks taking on the West Virginia Mountaineers.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Kansas vs West Virginia Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Kansas: (-490) | West Virginia: (+365)
• Spread: Kansas: -12.5 (-114) | West Virginia: +12.5 (-106)
• Total: 54.5 -- Over: (-110) | Under: (-110)

Kansas vs West Virginia Betting Trends

• Kansas has one win against the spread this season.
• Kansas owns one win ATS (1-1) as a 12.5-point favorite or greater this year.
• One of Kansas' three games this season has hit the over.
• West Virginia has posted two wins against the spread this year.
• No West Virginia game has gone over the point total this year.

Kansas vs West Virginia Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Jayhawks win (78.9%)

Kansas vs West Virginia Point Spread

West Virginia is a 12.5-point underdog against Kansas. West Virginia is -106 to cover the spread, and Kansas is -114.

Kansas vs West Virginia Over/Under

The over/under for Kansas-West Virginia on Sept. 20 is 54.5. The over is -110, and the under is -110.

Kansas vs West Virginia Moneyline

Looking at the moneyline for Kansas-West Virginia, Kansas is the favorite at -490, and West Virginia is +365.

Kansas vs. West Virginia Points Insights

Kansas vs. West Virginia Game Info

• Game day: Saturday, September 20, 2025
• Game time: 6 p.m. ET
• TV channel: Fox Sports 1
• Location: Lawrence, Kansas
• Stadium: David Booth Kansas Memorial Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Kansas vs. West Virginia analysis on FanDuel Research.