Giants vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 28

Odds updated as of 2:15 p.m.

The San Francisco Giants will face the Colorado Rockies in MLB action on Sunday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Giants vs Rockies Game Info

• San Francisco Giants (80-81) vs. Colorado Rockies (43-118)
• Date: Sunday, September 28, 2025
• Time: 3:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and COLR

Giants vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-310) | COL: (+250)
• Spread: SF: -1.5 (-140) | COL: +1.5 (+116)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Giants vs Rockies Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 14-11, 3.30 ERA vs McCade Brown (Rockies) - 0-4, 7.54 ERA

The Giants will give the ball to Logan Webb (14-11, 3.30 ERA), who is eyeing win No. 15 on the season, and the Rockies will counter with McCade Brown (0-4, 7.54 ERA). Webb's team is 15-18-0 against the spread this season in his starts. Webb's team is 14-15 this season when he starts and they are the moneyline favorite. The Rockies have gone 2-3-0 against the spread when Brown starts. The Rockies were the underdog on the moneyline for five Brown starts this season -- they lost every game.

Giants vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (69.2%)

Giants vs Rockies Moneyline

• San Francisco is a -310 favorite on the moneyline, while Colorado is a +250 underdog on the road.

Giants vs Rockies Spread

• The Rockies are at the Giants, and are +1.5 on the runline. The Rockies are -140 to cover the spread, and the Giants are +116.

Giants vs Rockies Over/Under

• An over/under of 7.5 has been set for Giants-Rockies on Sept. 28, with the over being -115 and the under -105.

Bet on San Francisco Giants vs. Colorado Rockies on FanDuel today!

Giants vs Rockies Betting Trends

• The Giants have been chosen as favorites in 93 games this year and have walked away with the win 49 times (52.7%) in those games.
• San Francisco has played as a favorite of -310 or more just one time this year and came away with a win in that game.
• The Giants and their opponents have gone over in 77 of their 160 games with a total set by sportsbooks this season.
• The Giants are 75-85-0 against the spread in their 160 games with a line set by sportsbooks this season.
• The Rockies have won 38 of the 151 games they were the underdog on the moneyline this season (25.2%).
• Colorado has a 3-20 record (winning only 13% of its games) when playing as a moneyline underdog of +250 or longer.
• The Rockies have played in 156 games with an over/under set, and have combined with opponents to go over the total 69 times (69-82-5).
• The Rockies have gone 63-93-0 ATS this season.

Giants Player Leaders

• Rafael Devers leads San Francisco in OBP (.372) and total hits (152) this season. He's batting .252 batting average while slugging .476.
• Among all qualifying hitters in baseball, he is 89th in batting average, ninth in on-base percentage, and 34th in slugging.
• Devers will look for his eighth straight game with a hit in this matchup. During his last 10 outings he is batting .211 with two doubles, three home runs, eight walks and six RBIs.
• Willy Adames has 22 doubles, two triples, 29 home runs and 80 walks. He's batting .224 and slugging .417 with an on-base percentage of .318.
• Among qualifying hitters, his batting average places him 142nd, his on-base percentage 97th, and his slugging percentage 86th.
• Jung Hoo Lee is batting .263 with a .405 slugging percentage and 53 RBI this year.
• Heliot Ramos leads San Francisco in slugging percentage (.402) thanks to 46 extra-base hits.
• Ramos has hit safely in five games in a row. During his last five outings he is batting .292 with three home runs and seven RBIs.

Rockies Player Leaders

• Hunter Goodman has racked up 149 hits with a .323 on-base percentage and a .521 slugging percentage, all club-highs for the Rockies. He's batting .278.
• Including all the qualified players in the majors, his batting average ranks 26th, his on-base percentage ranks 91st, and he is 14th in slugging.
• Mickey Moniak has 20 doubles, eight triples, 24 home runs and 22 walks while hitting .270. He's slugging .518 with an on-base percentage of .306.
• Jordan Beck is hitting .260 with 27 doubles, five triples, 16 home runs and 43 walks.
• Tyler Freeman is batting .281 with 20 doubles, two triples, two home runs and 34 walks.

Giants vs Rockies Head to Head

• 9/27/2025: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/26/2025: 6-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/3/2025: 10-8 SF (Favorite: Giants, Spread: -1.5, Total: 11.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/2/2025: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 10.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 9/1/2025: 8-2 SF (Favorite: Giants, Spread: -1.5, Total: 11.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/12/2025: 8-7 COL (Favorite: Giants, Spread: -1.5, Total: 11, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 6/11/2025: 10-7 SF (Favorite: Giants, Spread: -1.5, Total: 10.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/10/2025: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 11, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/4/2025: 9-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -390, Underdog Moneyline: +310)
• 5/3/2025: 6-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -290, Underdog Moneyline: +235)

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