East Carolina vs Charlotte Prediction, Odds, Picks, Best Bets for Week 11 2025

The college football schedule on Saturday includes the East Carolina Pirates facing the Charlotte 49ers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NCAA football betting odds.

East Carolina vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: East Carolina: (-10000) | Charlotte: (+2400)
• Spread: East Carolina: -29.5 (-110) | Charlotte: +29.5 (-110)
• Total: 56.5 -- Over: (-115) | Under: (-105)

East Carolina vs Charlotte Betting Trends

• Against the spread, East Carolina is 5-3-0 this year.
• East Carolina is unbeaten ATS (1-0) as a 29.5-point favorite or greater this year.
• This season, three of East Carolina's eight games have hit the over.
• Charlotte has won twice against the spread this season.
• Of eight Charlotte games so far this season, five have gone over the total.

East Carolina vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Pirates win (98.3%)

East Carolina vs Charlotte Point Spread

East Carolina is a 29.5-point favorite against Charlotte. East Carolina is -110 to cover the spread, and Charlotte is -110.

East Carolina vs Charlotte Over/Under

An over/under of 56.5 has been set for East Carolina-Charlotte on Nov. 8, with the over being -115 and the under -105.

East Carolina vs Charlotte Moneyline

Looking at the moneyline for East Carolina-Charlotte, East Carolina is the favorite at -10000, and Charlotte is +2400.

East Carolina vs. Charlotte Points Insights

East Carolina vs. Charlotte Game Info

• Game day: Saturday, November 8, 2025
• Game time: 3 p.m. ET
• TV channel: ESPN+
• Location: Greenville, North Carolina
• Stadium: Bagwell Field at Dowdy-Ficklen Stadium

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Check out even more in-depth East Carolina vs. Charlotte analysis on FanDuel Research.