Duke vs Kansas College Basketball Prediction, Odds, Picks, Best Bets for Nov. 18

The Duke Blue Devils (4-0) will try to continue a four-game winning streak when they host the Kansas Jayhawks (3-1) on November 18, 2025 at Madison Square Garden.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Kansas Game Info and Odds

• Game day: Tuesday, November 18, 2025
• Game time: 9 p.m. ET
• TV channel: ESPN
• Location: New York City, New York
• Arena: Madison Square Garden

See the betting insights and trends below before placing a wager on Tuesday's Duke-Kansas spread (Duke -10.5) or over/under (148.5 points).

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Duke vs. Kansas: ATS Betting Stats and Trends

• Duke went 25-14-0 ATS last season.
• Kansas went 15-18-0 ATS last year.
• In home games last season, the Blue Devils sported a worse record against the spread (11-6-0) compared to their ATS record on the road (9-2-0).
• The Jayhawks were better against the spread at home (8-9-0) than on the road (5-7-0) last year.

Duke vs. Kansas: Moneyline Betting Stats

• Duke won 33 of the 37 games it was favored on the moneyline last season (89.2%).
• The Blue Devils won all 24 games they played as a moneyline favorite with odds of -671 or shorter.
• Last season, Kansas was the underdog six times and won one of those games.
• The Jayhawks were not a bigger underdog last season than the +470 moneyline set for this game.
• Based on this contest's moneyline, Duke's implied win probability is 87.0%.

Duke vs. Kansas Head-to-Head Comparison

• Last year, Duke was 11th-best in the country on offense (83.2 points scored per game) and seventh-best on defense (62.8 points conceded).
• Duke was the 24th-best team in college basketball in rebounds per game (35.6) and 12th-best in rebounds allowed (27.3) last season.
• Duke was 17th-best in the country in assists (16.9 per game) last year.
• Duke was the ninth-best squad in the nation in turnovers per game (8.9) and 265th in turnovers forced (10.4) last season.
• Last season Kansas averaged 76.1 points per game (112th-ranked in college basketball) and gave up 69.6 points per contest (91st-ranked).
• Kansas was 43rd in the nation with 34.7 rebounds per game. Meanwhile, it ranked 211th with 31.7 rebounds allowed per contest.
• Kansas was one of the top teams in college basketball when it comes to assists, as it collected 17.7 per game (fourth-best in college basketball).
• Last year Kansas committed 11.5 turnovers per game (221st-ranked in college basketball) and forced 10.3 turnovers per contest (274th-ranked).

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