Dodgers vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 3:13 p.m.

The MLB's Monday slate includes the Los Angeles Dodgers facing the Minnesota Twins.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Twins Game Info

• Los Angeles Dodgers (58-42) vs. Minnesota Twins (48-51)
• Date: Monday, July 21, 2025
• Time: 10:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: SportsNet LA and MNNT

Dodgers vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-172) | MIN: (+144)
• Spread: LAD: -1.5 (+114) | MIN: +1.5 (-137)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Dodgers vs Twins Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 0-0, 1.00 ERA vs David Festa (Twins) - 3-3, 5.25 ERA

The probable starters are Shohei Ohtani for the Dodgers and David Festa (3-3) for the Twins. Ohtani and his team have a record of 2-3-0 against the spread when he starts. When Ohtani starts a game and his team is the favorite on the moneyline, they have a record of 3-2. The Twins have gone 6-3-0 ATS in Festa's nine starts that had a set spread. The Twins were the moneyline underdog for two Festa starts this season -- they split the games.

Dodgers vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (56.9%)

Dodgers vs Twins Moneyline

• The moneyline numbers for Dodgers vs. Twins reveal Los Angeles as the favorite (-172) and Minnesota as the underdog (+144) on the road.

Dodgers vs Twins Spread

• The Dodgers are hosting the Twins and are favored by 1.5 runs on the spread. The Dodgers are +114 to cover the runline, with the Twins being -137.

Dodgers vs Twins Over/Under

• An over/under of 8.5 has been set for Dodgers-Twins on July 21, with the over being -124 and the under +102.

Bet on Los Angeles Dodgers vs. Minnesota Twins on FanDuel today!

Dodgers vs Twins Betting Trends

• The Dodgers have won in 51, or 60%, of the 85 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has come away with a win 33 times in 52 chances when named as a favorite of at least -172 on the moneyline.
• The Dodgers and their opponents have hit the over in 54 of their 98 games with a total set by oddsmakers this season.
• The Dodgers are 41-57-0 against the spread in their 98 games with a line set by sportsbooks this season.
• The Twins have a 12-17 record in games they were the underdog on the moneyline (winning 41.4% of those games).
• Minnesota is 1-2 (winning only 33.3% of its games) when playing as a moneyline underdog of +144 or longer.
• The Twins have played in 95 games with an over/under set, and have combined with their opponents to go over the total 39 times (39-51-5).
• The Twins have put together a 48-47-0 record against the spread this season (covering 50.5% of the time).

Dodgers Player Leaders

• Ohtani has 105 hits to go with a slugging percentage of .610, both of which lead Los Angeles hitters this season. He has a .275 batting average and an on-base percentage of .380.
• He is 47th in batting average, ninth in on-base percentage, and third in slugging among all qualifying batters in MLB.
• Ohtani hopes to build on a two-game hitting streak in this matchup. During his last five outings he is batting .211 with two home runs, three walks and five RBIs.
• Mookie Betts has 13 doubles, a triple, 11 home runs and 36 walks. He's batting .240 and slugging .374 with an on-base percentage of .310.
• He is 120th in batting average, 115th in on-base percentage and 132nd in slugging among qualified hitters.
• Will Smith has 83 hits this season and a team-best OBP of .423.
• Andy Pages has been key for Los Angeles with 102 hits, an OBP of .321 plus a slugging percentage of .472.

Twins Player Leaders

• Byron Buxton has totaled 89 hits with a .350 on-base percentage and a .575 slugging percentage, all club-highs for the Twins. He's batting .289.
• Including all qualified players, he is 17th in batting average, while his on-base percentage is 47th and he is fifth in slugging.
• Trevor Larnach is batting .249 with 15 doubles, a triple, 13 home runs and 32 walks. He's slugging .414 with an on-base percentage of .316.
• He is currently 103rd in batting average, 105th in on-base percentage and 90th in slugging percentage among all qualified hitters.
• Willi Castro is batting .263 with 14 doubles, two triples, 10 home runs and 31 walks.
• Ty France is batting .245 with 16 doubles, six home runs and 15 walks.

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