Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 5:19 a.m.

The MLB slate on Friday includes the Los Angeles Dodgers taking on the San Francisco Giants.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (86-67) vs. San Francisco Giants (76-77)
• Date: Friday, September 19, 2025
• Time: 10:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: Apple TV+

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-168) | SF: (+142)
• Spread: LAD: -1.5 (+125) | SF: +1.5 (-150)
• Total: 8.5 -- Over: (-104) | Under: (-118)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Clayton Kershaw (Dodgers) - 10-2, 3.53 ERA vs Robbie Ray (Giants) - 11-7, 3.50 ERA

This contest's pitching matchup is set, as the Dodgers will send Clayton Kershaw (10-2) to the mound, while Robbie Ray (11-7) will take the ball for the Giants. Kershaw's team is 10-10-0 against the spread this season in his starts. Kershaw's team has won 70.6% of his starts when they are favored on the moneyline (12-5). The Giants have gone 19-11-0 ATS in Ray's 30 starts with a set spread. The Giants are 6-3 in Ray's nine starts this season that they were the underdog on the moneyline.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (60.2%)

Dodgers vs Giants Moneyline

• The moneyline numbers for Dodgers vs. Giants reveal Los Angeles as the favorite (-168) and San Francisco as the underdog (+142) on the road.

Dodgers vs Giants Spread

• The Dodgers are hosting the Giants and are favored by 1.5 runs on the spread. The Dodgers are +125 to cover the runline, with the Giants being -150.

Dodgers vs Giants Over/Under

• Dodgers versus Giants, on Sept. 19, has an over/under of 8.5, with the over being -104 and the under -118.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have won in 76, or 56.7%, of the 134 contests they have been named as odds-on favorites in this year.
• This season Los Angeles has been victorious 45 times in 77 chances when named as a favorite of at least -168 on the moneyline.
• The Dodgers and their opponents have gone over the total this season in 72 of their 151 opportunities.
• The Dodgers are 64-87-0 against the spread in their 151 games with a line set by sportsbooks this season.
• The Giants have won 27 of the 61 games they were the underdog on the moneyline this season (44.3%).
• San Francisco is 1-9 (winning just 10% of its games) when playing as a moneyline underdog of +142 or longer.
• The Giants have had an over/under set by oddsmakers 152 times, and have combined with opponents to go over the total in 72 of those games (72-72-8).
• The Giants have gone 72-80-0 ATS this season.

Dodgers Player Leaders

• Shohei Ohtani has 164 hits and an OBP of .395 to go with a slugging percentage of .617. All three of those stats are best among Los Angeles hitters this season. He has a .283 batting average, as well.
• Among qualifying hitters in the majors, his batting average ranks 20th, his on-base percentage ranks second, and he is second in slugging.
• Ohtani hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is hitting .342 with four doubles, three home runs, nine walks and five RBIs.
• Mookie Betts is hitting .260 with 22 doubles, two triples, 19 home runs and 58 walks. He's slugging .409 with an on-base percentage of .328.
• Among qualified hitters, he ranks 65th in batting average, 74th in on-base percentage and 89th in slugging percentage.
• Freddie Freeman has 156 hits this season and has a slash line of .295/.365/.495.
• Freeman takes a two-game hitting streak into this matchup. During his last five outings he is batting .333 with a double, a home run, two walks and three RBIs.
• Andy Pages is batting .277 with a .318 OBP and 81 RBI for Los Angeles this season.

Giants Player Leaders

• Rafael Devers has racked up 145 hits with a .372 on-base percentage, leading the Giants in both statistics. He's batting .253 and slugging .469.
• Including all the qualifying hitters in the big leagues, he is 84th in batting average, ninth in on-base percentage and 40th in slugging percentage.
• Jung Hoo Lee is hitting .261 with 30 doubles, 11 triples, eight home runs and 47 walks. He's slugging .403 with an on-base percentage of .325.
• Including all qualifying hitters, he ranks 59th in batting average, 80th in on-base percentage and 97th in slugging percentage.
• Willy Adames has 20 doubles, two triples, 28 home runs and 75 walks while hitting .226.
• Matt Chapman is batting .234 with 20 doubles, two triples, 21 home runs and 68 walks.

Dodgers vs Giants Head to Head

• 9/18/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/14/2025: 10-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/13/2025: 13-7 LAD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/12/2025: 5-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

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