Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 10:14 p.m.

The Los Angeles Dodgers will face the San Francisco Giants in MLB action on Friday.

We've got you covered, in terms of the most important information regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (86-67) vs. San Francisco Giants (76-77)
• Date: Friday, September 19, 2025
• Time: 10:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: Apple TV+

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-184) | SF: (+154)
• Spread: LAD: -1.5 (+112) | SF: +1.5 (-134)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Clayton Kershaw (Dodgers) - 10-2, 3.53 ERA vs Robbie Ray (Giants) - 11-7, 3.50 ERA

The Dodgers will give the nod to Clayton Kershaw (10-2) versus the Giants and Robbie Ray (11-7). Kershaw and his team have a record of 10-10-0 against the spread when he starts. Kershaw's team has a record of 12-5 this season when he starts and they are the favorite on the moneyline. When Ray starts, the Giants have gone 19-11-0 against the spread. The Giants have a 6-3 record in Ray's nine starts this season when they were the underdog on the moneyline.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (58.8%)

Dodgers vs Giants Moneyline

• The moneyline numbers for Dodgers vs. Giants reveal Los Angeles as the favorite (-184) and San Francisco as the underdog (+154) on the road.

Dodgers vs Giants Spread

• The Dodgers are favored by 1.5 runs at home against the Giants. The Dodgers are +112 to cover the spread, while the Giants are -134.

Dodgers vs Giants Over/Under

• Dodgers versus Giants, on Sept. 19, has an over/under of 8.5, with the over being -122 and the under -100.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been victorious in 76, or 56.7%, of the 134 contests they have been chosen as favorites in this season.
• This season Los Angeles has been victorious 38 times in 59 chances when named as a favorite of at least -184 on the moneyline.
• The Dodgers and their opponents have gone over the total this season in 72 of their 151 opportunities.
• The Dodgers are 64-87-0 against the spread in their 151 games with a line set by sportsbooks this season.
• The Giants have been the moneyline underdog 61 total times this season. They've finished 27-34 in those games.
• San Francisco is 1-4 (winning just 20% of its games) when playing as a moneyline underdog of +154 or longer.
• The Giants have combined with opponents to hit the over on the total 72 times this season for a 72-72-8 record against the over/under.
• The Giants have collected a 72-80-0 record against the spread this season (covering 47.4% of the time).

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.395), slugging percentage (.617) and total hits (164) this season. He has a .283 batting average.
• Among qualifying hitters in baseball, he ranks 20th in batting average, second in on-base percentage, and second in slugging.
• Ohtani hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is hitting .342 with four doubles, three home runs, nine walks and five RBIs.
• Mookie Betts is hitting .260 with 22 doubles, two triples, 19 home runs and 58 walks, while slugging .409 with an on-base percentage of .328.
• Among qualified hitters, he ranks 66th in batting average, 74th in on-base percentage and 89th in slugging percentage.
• Freddie Freeman is batting .295 with a .495 slugging percentage and 84 RBI this year.
• Freeman enters this game with two games in a row with at least one hit. In his last five games he is batting .333 with a double, a home run, two walks and three RBIs.
• Andy Pages has been key for Los Angeles with 151 hits, an OBP of .318 plus a slugging percentage of .463.

Giants Player Leaders

• Rafael Devers has put up an on-base percentage of .372 and has 145 hits, both team-high figures for the Giants. He's batting .253 and slugging .469.
• Including all qualified hitters in the majors, he ranks 84th in batting average, ninth in on-base percentage and 41st in slugging percentage.
• Jung Hoo Lee is hitting .261 with 30 doubles, 11 triples, eight home runs and 47 walks. He's slugging .403 with an on-base percentage of .325.
• Including all qualifying hitters, he ranks 60th in batting average, 80th in on-base percentage and 97th in slugging percentage.
• Willy Adames is batting .226 with 20 doubles, two triples, 28 home runs and 75 walks.
• Heliot Ramos' .390 slugging percentage paces his team.

Dodgers vs Giants Head to Head

• 9/18/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/14/2025: 10-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/13/2025: 13-7 LAD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/12/2025: 5-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!