Diamondbacks vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 9:12 p.m.

The Friday schedule in MLB includes a matchup between the Arizona Diamondbacks and the Philadelphia Phillies.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Phillies Game Info

• Arizona Diamondbacks (77-76) vs. Philadelphia Phillies (91-62)
• Date: Friday, September 19, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and NBCS-PH

Diamondbacks vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-124) | PHI: (+106)
• Spread: ARI: -1.5 (+155) | PHI: +1.5 (-188)
• Total: 9 -- Over: (-120) | Under: (-102)

Diamondbacks vs Phillies Probable Starting Pitchers

Probable Pitchers: Ryne Nelson (Diamondbacks) - 7-3, 3.34 ERA vs Taijuan Walker (Phillies) - 5-8, 4.17 ERA

The Diamondbacks will give the ball to Ryne Nelson (7-3, 3.34 ERA), who is eyeing win No. 8 on the season, and the Phillies will turn to Taijuan Walker (5-8, 4.17 ERA). When Nelson starts, his team is 12-9-0 against the spread this season. Nelson's team has won 60% of his starts when they are favored on the moneyline (6-4). The Phillies have a 10-8-0 record against the spread in Walker's starts. The Phillies have a 4-2 record in Walker's six starts this season when they were the underdog on the moneyline.

Diamondbacks vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (54.8%)

Diamondbacks vs Phillies Moneyline

• The Diamondbacks vs Phillies moneyline has Arizona as a -124 favorite, while Philadelphia is a +106 underdog on the road.

Diamondbacks vs Phillies Spread

• The Diamondbacks are favored by 1.5 runs at home versus the Phillies. The Diamondbacks are +155 to cover the spread, while the Phillies are -188.

Diamondbacks vs Phillies Over/Under

• A total of 9 runs has been set for the Diamondbacks-Phillies game on Sept. 19, with the over available at -120 and the under at -102.

Bet on Arizona Diamondbacks vs. Philadelphia Phillies on FanDuel today!

Diamondbacks vs Phillies Betting Trends

• The Diamondbacks have been favorites in 83 games this season and have come away with the win 44 times (53%) in those contests.
• Arizona has a record of 28-29 when favored by -124 or more this year.
• Contests with the Diamondbacks have gone over the total set by sportsbooks in 74 of 149 chances this season.
• The Diamondbacks have posted a record of 74-75-0 against the spread this season.
• The Phillies have gone 13-15 in games they were listed as the moneyline underdog (winning 46.4% of those games).
• When it has played as a moneyline underdog with odds of +106 or longer, Philadelphia has gone 9-8 (52.9%).
• In the 146 games bookmakers have set an over/under for the Phillies, they have combined with opponents to go over the total 61 times (61-76-9).
• The Phillies have covered 52.1% of their games this season, going 76-70-0 ATS.

Diamondbacks Player Leaders

• Geraldo Perdomo leads Arizona OPS (.852) this season. He has a .289 batting average, an on-base percentage of .391, and a slugging percentage of .461.
• Among all qualified hitters in MLB, he ranks 13th in batting average, fourth in on-base percentage, and 48th in slugging.
• Perdomo will look for his ninth straight game with a hit in this contest. During his last 10 games he is batting .333 with two doubles, a triple, two home runs, eight walks and six RBIs.
• Corbin Carroll has 139 hits, which is tops among Arizona batters this season. He's batting .258 with 77 extra-base hits. He's also slugging .545 with an on-base percentage of .339.
• Among qualifying batters, he ranks 70th in batting average, 51st in on-base percentage and sixth in slugging percentage.
• Carroll enters this game looking to extend his four-game hit streak. During his last five outings he is hitting .333 with a double, a triple, five walks and two RBIs.
• Ketel Marte has collected 123 base hits, an OBP of .372 and a slugging percentage of .497 this season.
• Gabriel Moreno has been key for Arizona with 70 hits, an OBP of .349 plus a slugging percentage of .451.

Phillies Player Leaders

• Kyle Schwarber has racked up 138 hits with a .370 on-base percentage, leading the Phillies in both statistics. He's batting .243 and slugging .567.
• Including all the qualifying hitters in MLB, his batting average ranks 102nd, his on-base percentage ranks 12th, and he is fourth in slugging.
• Bryce Harper is batting .263 with 32 doubles, 27 home runs and 66 walks. He's slugging .501 with an on-base percentage of .358.
• Including all qualified hitters, he is 54th in batting average, 25th in on-base percentage and 15th in slugging percentage.
• Bryson Stott has 20 doubles, three triples, 12 home runs and 52 walks while hitting .257.
• Nick Castellanos has 27 doubles, two triples, 16 home runs and 31 walks while batting .252.

Diamondbacks vs Phillies Head to Head

• 5/4/2025: 11-9 ARI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/3/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/2/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 12-5 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/10/2024: 11-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 3-2 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/8/2024: 6-4 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/23/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 6/22/2024: 12-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 6/21/2024: 5-4 ARI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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