Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 18

Odds updated as of 5:19 a.m.

In MLB action on Thursday, the Los Angeles Dodgers face the San Francisco Giants.

We've got you covered, in terms of the most important information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (85-67) vs. San Francisco Giants (76-76)
• Date: Thursday, September 18, 2025
• Time: 10:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: MLB Network, SportsNet LA, and NBCS-BA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-166) | SF: (+140)
• Spread: LAD: -1.5 (+138) | SF: +1.5 (-166)
• Total: 7.5 -- Over: (-100) | Under: (-122)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Yoshinobu Yamamoto (Dodgers) - 11-8, 2.66 ERA vs Logan Webb (Giants) - 14-10, 3.34 ERA

The probable pitchers are Yoshinobu Yamamoto (11-8) for the Dodgers and Logan Webb (14-10) for the Giants. Yamamoto and his team are 12-16-0 ATS this season when he starts. Yamamoto's team is 14-13 this season when he starts and they are the moneyline favorite. The Giants have a 14-17-0 ATS record in Webb's 31 starts with a set spread. The Giants were the underdog on the moneyline for three Webb starts this season -- they won each time.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (60%)

Dodgers vs Giants Moneyline

• Looking at the moneyline for Giants-Dodgers, San Francisco is the underdog at +140, and Los Angeles is -166 playing at home.

Dodgers vs Giants Spread

• The Giants are at the Dodgers, and are +1.5 on the runline. The Giants are +138 to cover the spread, and the Dodgers are -166.

Dodgers vs Giants Over/Under

• Dodgers versus Giants on Sept. 18 has an over/under of 7.5 runs, with the odds on the over -100 and the under set at -122.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have come away with 75 wins in the 133 contests they have been listed as the favorites in this season.
• This season Los Angeles has been victorious 44 times in 79 chances when named as a favorite of at least -166 on the moneyline.
• The Dodgers and their opponents have hit the over in 72 of their 150 games with a total set by oddsmakers this season.
• The Dodgers have posted a record of 64-86-0 against the spread this season.
• The Giants are 27-33 in games they were the underdog on the moneyline (winning 45% of those games).
• In games it has played as a moneyline underdog with odds of +140 or longer, San Francisco has a 1-8 record (winning just 11.1% of its games).
• The Giants have played in 151 games with an over/under set, and have combined with opponents to go over the total 72 times (72-71-8).
• The Giants have put together a 71-80-0 record against the spread this season.

Dodgers Player Leaders

• Shohei Ohtani has 162 hits and an OBP of .394 to go with a slugging percentage of .614. All three of those stats are tops among Los Angeles hitters this season. He has a .282 batting average, as well.
• Among all qualified hitters in the majors, he is 20th in batting average, second in on-base percentage, and second in slugging.
• Ohtani has hit safely in five games in a row. In his last five games he is hitting .348 with a double, three home runs, three walks and three RBIs.
• Mookie Betts is hitting .261 with 22 doubles, two triples, 19 home runs and 57 walks. He's slugging .411 with an on-base percentage of .329.
• He is 62nd in batting average, 75th in on-base percentage and 87th in slugging in MLB.
• Freddie Freeman is batting .295 with a .497 slugging percentage and 83 RBI this year.
• Andy Pages has 25 home runs, 81 RBI and a batting average of .278 this season.
• Pages heads into this game on a four-game hitting streak. During his last five outings he is batting .421 with two doubles, a home run, a walk and an RBI.

Giants Player Leaders

• Rafael Devers has put up a team-best OBP (.373), while pacing the Giants in hits (145). He's batting .254 and slugging.
• Including all qualifying hitters in the majors, his batting average places him 84th, his on-base percentage ranks eighth, and he is 39th in slugging.
• Jung Hoo Lee is hitting .262 with 30 doubles, 11 triples, eight home runs and 46 walks. He's slugging .406 with an on-base percentage of .326.
• He ranks 59th in batting average, 78th in on-base percentage and 93rd in slugging percentage in the majors.
• Willy Adames has 20 doubles, two triples, 28 home runs and 73 walks while batting .227.
• Matt Chapman is batting .235 with 20 doubles, two triples, 21 home runs and 66 walks.

Dodgers vs Giants Head to Head

• 9/14/2025: 10-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/13/2025: 13-7 LAD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/12/2025: 5-1 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2024: 6-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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