Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 12

Odds updated as of 8:11 a.m.

The Los Angeles Dodgers versus the San Francisco Giants is on the MLB schedule for Friday.

We've got you covered, in terms of the most important information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (82-64) vs. San Francisco Giants (74-72)
• Date: Friday, September 12, 2025
• Time: 10:15 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: MLB Network, NBCS-BA, and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-154) | SF: (+130)
• Spread: LAD: -1.5 (+116) | SF: +1.5 (-140)
• Total: 7.5 -- Over: (-114) | Under: (-106)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Yoshinobu Yamamoto (Dodgers) - 11-8, 2.72 ERA vs Justin Verlander (Giants) - 3-10, 4.09 ERA

The probable pitchers are Yoshinobu Yamamoto (11-8) for the Dodgers and Justin Verlander (3-10) for the Giants. Yamamoto's team is 12-15-0 against the spread in his starts this season. When Yamamoto starts a game and his team is the favorite on the moneyline, they have a record of 14-12. The Giants have a 7-18-0 record against the spread in Verlander's starts. The Giants have been the underdog on the moneyline in 11 of Verlander's starts this season, and they went 3-8 in those games.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (55.1%)

Dodgers vs Giants Moneyline

• The moneyline numbers for Dodgers vs. Giants reveal Los Angeles as the favorite (-154) and San Francisco as the underdog (+130) despite being the home team.

Dodgers vs Giants Spread

• The Giants are +1.5 on the spread (-140 to cover), and Los Angeles is +116 to cover the runline.

Dodgers vs Giants Over/Under

• A combined run total of 7.5 has been set for Dodgers-Giants on Sept. 12, with the over at -114 and the under at -106.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been victorious in 73, or 57%, of the 128 contests they have been chosen as favorites in this season.
• Los Angeles has a record of 54-39 in contests when bookmakers favor them by -154 or more on the moneyline.
• The Dodgers and their opponents have gone over the total this season in 68 of their 144 opportunities.
• In 144 games with a line this season, the Dodgers have a mark of 60-84-0 against the spread.
• The Giants have won 26 of the 56 games they were the moneyline underdog this season (46.4%).
• In games it has played as a moneyline underdog with odds of +130 or longer, San Francisco has gone 6-11 (35.3%).
• The Giants have combined with opponents to go over the total 69 times this season for a 69-69-7 record against the over/under.
• The Giants have put together a 68-77-0 record against the spread this season (covering 46.9% of the time).

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles in OBP (.391), slugging percentage (.609) and total hits (154) this season. He has a .280 batting average.
• He ranks 24th in batting average, fourth in on-base percentage, and second in slugging among all qualifying batters in the majors.
• Ohtani has hit safely in five straight games. In his last five games he is batting .375 with a double, two home runs, six walks and five RBIs.
• Mookie Betts has 21 doubles, two triples, 18 home runs and 54 walks. He's batting .260 and slugging .409 with an on-base percentage of .328.
• Among all qualifying hitters, he is 74th in batting average, 77th in on-base percentage and 89th in slugging percentage.
• Betts heads into this matchup looking to extend his seven-game hit streak. In his last 10 games he is batting .395 with three doubles, a triple, four home runs, a walk and 15 RBIs.
• Freddie Freeman has 145 hits this season and has a slash line of .292/.364/.495.
• Andy Pages has 24 home runs, 80 RBI and a batting average of .273 this season.
• Pages has safely hit in two games in a row. During his last five outings he is hitting .294 with a double and an RBI.

Giants Player Leaders

• Rafael Devers has accumulated an on-base percentage of .378 and has 142 hits, both team-high numbers for the Giants. He's batting .260 and slugging .486.
• Including all the qualified hitters in the majors, he is 74th in batting average, ninth in on-base percentage and 27th in slugging percentage.
• Jung Hoo Lee is batting .269 with 30 doubles, 11 triples, eight home runs and 44 walks. He's slugging .416 with an on-base percentage of .330.
• Including all qualifying hitters, he ranks 42nd in batting average, 69th in on-base percentage and 84th in slugging percentage.
• Willy Adames is batting .229 with 19 doubles, two triples, 28 home runs and 69 walks.
• Matt Chapman has 19 doubles, two triples, 21 home runs and 63 walks while batting .243.

Dodgers vs Giants Head to Head

• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2024: 6-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/24/2024: 8-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/23/2024: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/22/2024: 3-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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