Dodgers vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 12

Odds updated as of 10:11 p.m.

On Friday in MLB, the Los Angeles Dodgers are up against the San Francisco Giants.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Dodgers vs Giants Game Info

• Los Angeles Dodgers (82-64) vs. San Francisco Giants (74-72)
• Date: Friday, September 12, 2025
• Time: 10:15 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: MLB Network, NBCS-BA, and SportsNet LA

Dodgers vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-158) | SF: (+134)
• Spread: LAD: -1.5 (+115) | SF: +1.5 (-138)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Dodgers vs Giants Probable Starting Pitchers

Probable Pitchers: Yoshinobu Yamamoto (Dodgers) - 11-8, 2.72 ERA vs Justin Verlander (Giants) - 3-10, 4.09 ERA

The Dodgers will give the nod to Yoshinobu Yamamoto (11-8) against the Giants and Justin Verlander (3-10). Yamamoto and his team have a record of 12-15-0 against the spread when he starts. When Yamamoto starts a game and his team is the favorite on the moneyline, they have a record of 14-12. The Giants have a 7-18-0 record against the spread in Verlander's starts. The Giants are 3-8 in Verlander's 11 starts this season that they were the moneyline underdog.

Dodgers vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (55.1%)

Dodgers vs Giants Moneyline

• Los Angeles is the favorite, -158 on the moneyline, while San Francisco is a +134 underdog despite being at home.

Dodgers vs Giants Spread

• The Giants are +1.5 on the run line against the Dodgers. The Giants are -138 to cover, and the Dodgers are +115.

Dodgers vs Giants Over/Under

• Dodgers versus Giants, on Sept. 12, has an over/under of 7.5, with the over being -112 and the under -108.

Bet on Los Angeles Dodgers vs. San Francisco Giants on FanDuel today!

Dodgers vs Giants Betting Trends

• The Dodgers have been victorious in 73, or 57%, of the 128 contests they have been chosen as favorites in this season.
• Los Angeles has a record of 49-35 when favored by -158 or more this year.
• Contests with the Dodgers have gone over the total set by oddsmakers in 68 of 144 chances this season.
• The Dodgers are 60-84-0 against the spread in their 144 games with a line set by sportsbooks this season.
• The Giants have been the underdog on the moneyline 56 total times this season. They've finished 26-30 in those games.
• When playing as a moneyline underdog with odds of +134 or longer, San Francisco has gone 4-9 (30.8%).
• The Giants have had an over/under set by oddsmakers 145 times, and have combined with opponents to go over the total in 69 of those games (69-69-7).
• The Giants have collected a 68-77-0 record ATS this season (covering 46.9% of the time).

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles with 154 hits and an OBP of .391, plus a team-best slugging percentage of .609. He's batting .280.
• Among all qualified batters in baseball, he ranks 24th in batting average, fourth in on-base percentage, and second in slugging.
• Ohtani has recorded at least one hit in five straight games. During his last five outings he is hitting .375 with a double, two home runs, six walks and five RBIs.
• Mookie Betts has 21 doubles, two triples, 18 home runs and 54 walks. He's batting .260 and slugging .409 with an on-base percentage of .328.
• Among all qualified hitters, he is 73rd in batting average, 77th in on-base percentage and 90th in slugging percentage.
• Betts has picked up a hit in seven straight games. During his last 10 games he is batting .395 with three doubles, a triple, four home runs, a walk and 15 RBIs.
• Freddie Freeman has 145 hits this season and has a slash line of .292/.364/.495.
• Andy Pages is batting .273 with a .315 OBP and 80 RBI for Los Angeles this season.
• Pages takes a two-game hitting streak into this game. In his last five games he is hitting .294 with a double and an RBI.

Giants Player Leaders

• Rafael Devers has 142 hits with a .378 on-base percentage, leading the Giants in both statistics. He's batting .260 and slugging .486.
• Including all the qualified players in MLB, his batting average puts him 73rd, his on-base percentage is ninth, and he is 26th in slugging.
• Jung Hoo Lee is batting .269 with 30 doubles, 11 triples, eight home runs and 44 walks. He's slugging .416 with an on-base percentage of .330.
• Including all qualified hitters, he ranks 42nd in batting average, 69th in on-base percentage and 85th in slugging percentage.
• Willy Adames has 19 doubles, two triples, 28 home runs and 69 walks while batting .229.
• Matt Chapman is hitting .243 with 19 doubles, two triples, 21 home runs and 63 walks.

Dodgers vs Giants Head to Head

• 7/13/2025: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/12/2025: 2-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/11/2025: 8-7 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/15/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/14/2025: 11-5 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/13/2025: 6-2 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/25/2024: 6-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/24/2024: 8-3 SF (Favorite: Dodgers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/23/2024: 5-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/22/2024: 3-2 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)

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