Astros vs Braves Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 12

Odds updated as of 4:16 a.m.

The Friday slate in MLB includes a matchup between the Houston Astros and the Atlanta Braves.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Astros vs Braves Game Info

• Houston Astros (79-68) vs. Atlanta Braves (65-81)
• Date: Friday, September 12, 2025
• Time: 7:15 p.m. ET
• Venue: Truist Park -- Atlanta, Georgia
• Coverage: FDSSO and SCHN

Astros vs Braves Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-132) | ATL: (+112)
• Spread: HOU: -1.5 (+128) | ATL: +1.5 (-154)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Astros vs Braves Probable Starting Pitchers

Probable Pitchers: TBA (Astros) vs Hurston Waldrep (Braves) - 4-0, 0.00 ERA

The Braves will look to Waldrep (4-0, 16.71), while the Astros' starter for this game has yet to be determined. The Braves have gone 4-2-0 against the spread when Waldrep starts. The Braves were the underdog on the moneyline for two Waldrep starts this season -- they won both.

Astros vs Braves Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Braves win (52.6%)

Astros vs Braves Moneyline

• Atlanta is the underdog, +112 on the moneyline, while Houston is a -132 favorite despite being on the road.

Astros vs Braves Spread

• The Astros are 1.5-run road favorites on the runline against the Braves. The Astros are +128 to cover, and the Braves are -154.

Astros vs Braves Over/Under

• The over/under for Astros-Braves on Sept. 12 is 8.5. The over is -100, and the under is -122.

Bet on Houston Astros vs. Atlanta Braves on FanDuel today!

Astros vs Braves Betting Trends

• The Astros have won in 48, or 52.7%, of the 91 contests they have been named as odds-on favorites in this year.
• This year Houston has won 30 of 54 games when listed as at least -132 on the moneyline.
• The Astros' games have gone over the total in 65 of their 146 opportunities.
• The Astros have an against the spread mark of 72-74-0 in 146 games with a line this season.
• The Braves have put together a 15-33 record in games they were listed as the moneyline underdog (winning 31.2% of those games).
• Atlanta has an 8-18 record (winning just 30.8% of its games) when playing as a moneyline underdog of +112 or longer.
• The Braves have played in 140 games with a set over/under, and have combined with their opponents to go over the total 60 times (60-72-8).
• The Braves have collected a 61-79-0 record against the spread this season (covering 43.6% of the time).

Astros Player Leaders

• Jose Altuve leads Houston with a slugging percentage of .437, fueled by 47 extra-base hits. He has a .261 batting average and an on-base percentage of .325.
• Among qualifying batters in baseball, his batting average ranks 71st, his on-base percentage ranks 86th, and he is 72nd in slugging.
• Jeremy Pena has 139 hits and an OBP of .359, both of which lead the Astros this season. He's batting .300 and slugging .463.
• His batting average is sixth among qualified players, his on-base percentage 21st, and his slugging percentage 44th.
• Yainer Diaz is batting .255 with a .420 slugging percentage and 63 RBI this year.
• Carlos Correa has been key for Houston with 134 hits, an OBP of .329 plus a slugging percentage of .405.
• Correa has hit safely in three straight games. In his last five games he is batting .238 with two home runs, a walk and three RBIs.

Braves Player Leaders

• Matt Olson has 151 hits with a .368 on-base percentage and a .463 slugging percentage, all club-bests for the Braves. He's batting .271.
• Including all qualified hitters, he ranks 39th in batting average, while his on-base percentage is 11th and he is 44th in slugging.
• Ozzie Albies is batting .241 with 21 doubles, two triples, 16 home runs and 50 walks. He's slugging .371 with an on-base percentage of .306.
• Including all qualifying players, he ranks 111th in batting average, 118th in on-base percentage and 132nd in slugging percentage.
• Michael Harris II has 22 doubles, six triples, 17 home runs and 14 walks while batting .241.
• Marcell Ozuna is batting .228 with 17 doubles, 20 home runs and 87 walks.

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