Dodgers vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 3:12 p.m.

The MLB schedule on Thursday includes the Los Angeles Dodgers taking on the Arizona Diamondbacks.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Dodgers vs Diamondbacks Game Info

• Los Angeles Dodgers (89-69) vs. Arizona Diamondbacks (80-78)
• Date: Thursday, September 25, 2025
• Time: 3:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and SportsNet LA

Dodgers vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-146) | ARI: (+124)
• Spread: LAD: -1.5 (+112) | ARI: +1.5 (-134)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Dodgers vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Yoshinobu Yamamoto (Dodgers) - 11-8, 2.58 ERA vs Jalen Beeks (Diamondbacks) - 5-2, 3.67 ERA

The probable starters are Yoshinobu Yamamoto (11-8) for the Dodgers and Jalen Beeks (5-2) for the Diamondbacks. Yamamoto's team is 12-17-0 against the spread in his starts this season. Yamamoto's team has a record of 15-13 this season when he starts and they are the favorite on the moneyline. Beeks has started just one game with a set spread, which the Diamondbacks covered. The Diamondbacks were the moneyline underdog for one Beeks start this season -- they won.

Dodgers vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (56.3%)

Dodgers vs Diamondbacks Moneyline

• Looking at the moneyline for Diamondbacks-Dodgers, Arizona is the underdog at +124, and Los Angeles is -146 playing on the road.

Dodgers vs Diamondbacks Spread

• The Diamondbacks are +1.5 on the spread (-134 to cover), and Los Angeles is +112 to cover the runline.

Dodgers vs Diamondbacks Over/Under

• An over/under of 8.5 has been set for Dodgers-Diamondbacks on Sept. 25, with the over being -110 and the under -110.

Bet on Los Angeles Dodgers vs. Arizona Diamondbacks on FanDuel today!

Dodgers vs Diamondbacks Betting Trends

• The Dodgers have come away with 79 wins in the 139 contests they have been listed as the favorites in this season.
• This year Los Angeles has won 59 of 104 games when listed as at least -146 on the moneyline.
• The Dodgers' games have gone over the total in 75 of their 156 opportunities.
• The Dodgers are 66-90-0 against the spread in their 156 games with a line set by sportsbooks this season.
• The Diamondbacks have been the moneyline underdog 66 total times this season. They've gone 33-33 in those games.
• Arizona has a 14-8 record (winning 63.6% of its games) when playing as a moneyline underdog of +124 or longer.
• The Diamondbacks have played in 154 games with a set over/under, and have combined with opponents to go over the total 77 times (77-69-8).
• The Diamondbacks have collected a 78-76-0 record ATS this season.

Dodgers Player Leaders

• Shohei Ohtani leads Los Angeles with 168 hits and an OBP of .392, plus a team-best slugging percentage of .617. He's batting .281.
• Among the qualifying hitters in MLB, his batting average ranks 23rd, his on-base percentage ranks third, and he is second in slugging.
• Mookie Betts is batting .262 with 23 doubles, two triples, 20 home runs and 60 walks, while slugging .412 with an on-base percentage of .329.
• His batting average ranks 60th among qualified players, his on-base percentage 72nd, and his slugging percentage 85th.
• Betts brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .316 with a double, a home run, two walks and two RBIs.
• Freddie Freeman is batting .291 with a .485 slugging percentage and 85 RBI this year.
• Freeman has logged a hit or more in four straight games. During his last five outings he is hitting .200 with a walk and an RBI.
• Andy Pages is batting .276 with a .316 OBP and 84 RBI for Los Angeles this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has an on-base percentage of .390 and a slugging percentage of .459. Both lead the Diamondbacks. He's batting .290.
• Including all qualifying players in the big leagues, he ranks 15th in batting average, fourth in on-base percentage and 47th in slugging percentage.
• Corbin Carroll leads his team with 146 hits. He has a batting average of .262 while slugging .548 with an on-base percentage of .344.
• Including all qualified hitters, he is 60th in batting average, 47th in on-base percentage and fifth in slugging percentage.
• Ketel Marte is hitting .284 with 27 doubles, 26 home runs and 63 walks.
• Gabriel Moreno is batting .288 with 12 doubles, a triple, nine home runs and 27 walks.

Dodgers vs Diamondbacks Head to Head

• 9/24/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/23/2025: 5-4 ARI (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/31/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/30/2025: 6-1 ARI (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/29/2025: 3-0 ARI (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/21/2025: 3-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/20/2025: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 5/19/2025: 9-5 ARI (Favorite: Dodgers, Spread: -1.5, Total: 10.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/11/2025: 8-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/10/2025: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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