Cubs vs Mets Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 4:12 a.m.

The Chicago Cubs versus the New York Mets is on the MLB schedule for Thursday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Cubs vs Mets Game Info

• Chicago Cubs (89-69) vs. New York Mets (81-77)
• Date: Thursday, September 25, 2025
• Time: 7:40 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and SNY

Cubs vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-108) | NYM: (-108)
• Spread: CHC: +1.5 (-194) | NYM: -1.5 (+160)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Cubs vs Mets Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 9-7, 3.37 ERA vs Nolan McLean (Mets) - 4-1, 1.27 ERA

The probable pitchers are Shota Imanaga (9-7) for the Cubs and Nolan McLean (4-1) for the Mets. Imanaga's team is 9-14-0 against the spread in his starts this season. Imanaga's team has a record of 9-7 this season when he starts and they are the favorite on the moneyline. When McLean starts, the Mets have gone 5-2-0 against the spread. The Mets were named the moneyline underdog for two McLean starts this season -- they won both.

Cubs vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (53.1%)

Cubs vs Mets Moneyline

• New York is a -108 underdog on the moneyline, while Chicago is a -108 favorite at home.

Cubs vs Mets Spread

Cubs vs Mets Over/Under

• The over/under for the Cubs versus Mets game on Sept. 25 has been set at 7.5, with -106 odds on the over and -114 odds on the under.

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Cubs vs Mets Betting Trends

• The Cubs have come away with 67 wins in the 105 contests they have been listed as the favorites in this season.
• This season Chicago has come away with a win 69 times in 110 chances when named as a favorite of at least -108 on the moneyline.
• The Cubs and their opponents have hit the over in 71 of their 153 games with a total set by oddsmakers this season.
• The Cubs are 72-81-0 against the spread in their 153 games with a line set by sportsbooks this season.
• The Mets have won 36.6% of the games this season they were the underdog on the moneyline (15-26).
• When playing as a moneyline underdog with odds of -108 or longer, New York has a record of 15-26 (36.6%).
• The Mets have had an over/under set by oddsmakers 151 times, and have combined with opponents to go over the total in 71 of those games (71-72-8).
• The Mets have gone 70-81-0 against the spread this season.

Cubs Player Leaders

• Nico Hoerner has an OPS of .746, fueled by an OBP of .350 and a team-best slugging percentage of .396 this season. He has a .301 batting average.
• Among qualified hitters in baseball, his batting average ranks seventh, his on-base percentage ranks 37th, and he is 108th in slugging.
• Hoerner hopes to build on a two-game hitting streak in this matchup. During his last five outings he is hitting .318 with a walk and an RBI.
• Pete Crow-Armstrong has 37 doubles, four triples, 29 home runs and 29 walks. He's batting .244 and slugging .473 with an on-base percentage of .284.
• His batting average ranks 106th among qualified players, his on-base percentage 140th, and his slugging percentage 40th.
• Ian Happ has collected 134 base hits, an OBP of .342 and a slugging percentage of .421 this season.
• Happ takes a three-game hitting streak into this game. During his last five outings he is hitting .238 with three doubles, a walk and five RBIs.
• Michael Busch has 131 hits, which ranks first among Chicago hitters this season, while batting .256 with 58 extra-base hits.

Mets Player Leaders

• Juan Soto has racked up an on-base percentage of .399 and has 150 hits, both team-high numbers for the Mets. He's batting .267 and slugging .536.
• Including all qualifying hitters in the big leagues, he ranks 43rd in batting average, second in on-base percentage and eighth in slugging percentage.
• Soto heads into this game on an eight-game hitting streak. During his last 10 games he is hitting .325 with two doubles, four home runs, six walks and nine RBIs.
• Francisco Lindor paces his team with a .459 slugging percentage. He has a batting average of .267 with an on-base percentage of .342.
• Including all qualifying hitters, he ranks 43rd in batting average, 51st in on-base percentage and 47th in slugging percentage.
• Pete Alonso is hitting .271 with 38 doubles, a triple, 37 home runs and 60 walks.
• Brandon Nimmo has 27 doubles, 25 home runs and 49 walks while hitting .261.

Cubs vs Mets Head to Head

• 9/24/2025: 10-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/23/2025: 9-7 NYM (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/11/2025: 6-2 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/10/2025: 6-5 CHC (Favorite: Mets, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/9/2025: 7-2 NYM (Favorite: Mets, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/23/2024: 5-2 NYM (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/22/2024: 8-1 CHC (Favorite: Mets, Spread: -1.5, Total: 11.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/21/2024: 11-1 NYM (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/2/2024: 7-6 NYM (Favorite: Mets, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/1/2024: 1-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)

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