Dodgers vs Diamondbacks Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 5:13 a.m.

The Wednesday slate in MLB includes a matchup between the Los Angeles Dodgers and the Arizona Diamondbacks.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Dodgers vs Diamondbacks Game Info

• Los Angeles Dodgers (88-69) vs. Arizona Diamondbacks (80-77)
• Date: Wednesday, September 24, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: ARID and SportsNet LA

Dodgers vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-156) | ARI: (+132)
• Spread: LAD: -1.5 (+104) | ARI: +1.5 (-125)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Dodgers vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Blake Snell (Dodgers) - 5-4, 2.44 ERA vs Ryne Nelson (Diamondbacks) - 7-3, 3.34 ERA

The probable pitchers are Blake Snell (5-4) for the Dodgers and Ryne Nelson (7-3) for the Diamondbacks. Snell and his team have a record of 4-6-0 against the spread when he starts. Snell's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 6-4. When Nelson starts, the Diamondbacks are 12-10-0 against the spread. The Diamondbacks have been the underdog on the moneyline in nine of Nelson's starts this season, and they went 5-4 in those matchups.

Dodgers vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (58.4%)

Dodgers vs Diamondbacks Moneyline

• Los Angeles is the favorite, -156 on the moneyline, while Arizona is a +132 underdog despite being at home.

Dodgers vs Diamondbacks Spread

• The Diamondbacks are at +1.5 on the runline against the Dodgers. The Diamondbacks are -125 to cover the spread, and the Dodgers are +104.

Dodgers vs Diamondbacks Over/Under

• A total of 8.5 runs has been set for the Dodgers-Diamondbacks contest on Sept. 24, with the over available at -115 and the under at -105.

Bet on Los Angeles Dodgers vs. Arizona Diamondbacks on FanDuel today!

Dodgers vs Diamondbacks Betting Trends

• The Dodgers have come away with 78 wins in the 138 contests they have been listed as the favorites in this season.
• This season Los Angeles has come away with a win 55 times in 94 chances when named as a favorite of at least -156 on the moneyline.
• The Dodgers and their opponents have gone over the total this season in 74 of their 155 opportunities.
• The Dodgers are 66-89-0 against the spread in their 155 games with a line set by sportsbooks this season.
• The Diamondbacks have won 50.8% of the games this season they were the underdog on the moneyline (33-32).
• Arizona is 8-6 (winning 57.1% of its games) when playing as a moneyline underdog of +132 or longer.
• The Diamondbacks have played in 153 games with a set over/under, and have combined with opponents to go over the total 76 times (76-69-8).
• The Diamondbacks have a 77-76-0 record against the spread this season.

Dodgers Player Leaders

• Shohei Ohtani has 167 hits and an OBP of .394 to go with a slugging percentage of .617. All three of those stats rank first among Los Angeles hitters this season. He has a .282 batting average, as well.
• Among the qualified hitters in the majors, his batting average ranks 21st, his on-base percentage ranks third, and he is second in slugging.
• Mookie Betts is hitting .258 with 23 doubles, two triples, 20 home runs and 60 walks. He's slugging .410 with an on-base percentage of .327.
• Among qualified hitters, his batting average ranks him 71st, his on-base percentage 76th, and his slugging percentage 89th.
• Freddie Freeman has 159 hits this season and has a slash line of .292/.363/.487.
• Freeman brings a three-game hitting streak into this matchup. In his last five games he is batting .211 with a walk and two RBIs.
• Andy Pages is batting .277 with a .317 OBP and 82 RBI for Los Angeles this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has put up a .391 on-base percentage and a .461 slugging percentage, both team-best averages for the Diamondbacks. He's batting .291.
• He is 14th in batting average, fifth in on-base percentage and 48th in slugging percentage among all qualified hitters in the big leagues.
• Perdomo enters this game on a 12-game hitting streak. During his last 10 games he is batting .395 with four doubles, a triple, a home run, six walks and five RBIs.
• Corbin Carroll has 144 hits to pace his team. He has a batting average of .260 while slugging .545 with an on-base percentage of .341.
• Including all qualified players, his batting average puts him 62nd, his on-base percentage is 51st, and he is sixth in slugging.
• Ketel Marte has 26 doubles, 26 home runs and 63 walks while hitting .280.
• Gabriel Moreno is hitting .287 with 12 doubles, a triple, nine home runs and 26 walks.

Dodgers vs Diamondbacks Head to Head

• 9/23/2025: 5-4 ARI (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/31/2025: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/30/2025: 6-1 ARI (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/29/2025: 3-0 ARI (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/21/2025: 3-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/20/2025: 4-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 5/19/2025: 9-5 ARI (Favorite: Dodgers, Spread: -1.5, Total: 10.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/11/2025: 8-1 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/10/2025: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/9/2025: 14-11 LAD (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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