Angels vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 9:12 p.m.

On Wednesday in MLB, the Kansas City Royals are playing the Los Angeles Angels.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Royals vs Angels Game Info

• Kansas City Royals (79-78) vs. Los Angeles Angels (70-87)
• Date: Wednesday, September 24, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and FDSKC

Royals vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-112) | LAA: (-104)
• Spread: KC: -1.5 (+150) | LAA: +1.5 (-182)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Royals vs Angels Probable Starting Pitchers

Probable Pitchers: Stephen Kolek (Royals) - 5-6, 3.54 ERA vs Yusei Kikuchi (Angels) - 6-11, 4.05 ERA

This contest's pitching matchup is set, as the Royals will send Stephen Kolek (5-6) to the mound, while Yusei Kikuchi (6-11) will answer the bell for the Angels. Kolek's team is 12-6-0 against the spread in his starts this season. When Kolek starts a game and his team is the favorite on the moneyline, they have a record of 2-4. When Kikuchi starts, the Angels have gone 17-15-0 against the spread. The Angels have been the moneyline underdog in 20 of Kikuchi's starts this season, and they went 6-14 in those games.

Royals vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (53.2%)

Royals vs Angels Moneyline

• Los Angeles is the underdog, -104 on the moneyline, while Kansas City is a -112 favorite despite being on the road.

Royals vs Angels Spread

• The Royals are at the Angels and are favored by 1.5 runs (+150 to cover) on the runline. Los Angeles is -182 to cover.

Royals vs Angels Over/Under

• The over/under for the Royals versus Angels game on Sept. 24 has been set at 8.5, with -102 odds on the over and -120 odds on the under.

Bet on Kansas City Royals vs. Los Angeles Angels on FanDuel today!

Royals vs Angels Betting Trends

• The Royals have been favorites in 64 games this season and have come away with the win 37 times (57.8%) in those contests.
• This year Kansas City has won 37 of 64 games when listed as at least -112 on the moneyline.
• Contests with the Royals have gone over the total set by oddsmakers in 68 of 155 chances this season.
• The Royals have an against the spread mark of 76-79-0 in 155 games with a line this season.
• The Angels are 50-66 in games they were the underdog on the moneyline (winning 43.1% of those games).
• When playing as a moneyline underdog with odds of -104 or longer, Los Angeles has a 47-61 record (winning 43.5% of its games).
• The Angels have had an over/under set by oddsmakers 155 times, and have combined with opponents to go over the total in 83 of those games (83-67-5).
• The Angels are 81-74-0 against the spread this season.

Royals Player Leaders

• Bobby Witt Jr. leads Kansas City with 176 hits and a team-best slugging percentage of .502. He's batting .293 with an on-base percentage of .351.
• Among qualifying hitters, he is 11th in batting average, his on-base percentage ranks 36th, and he is 16th in slugging.
• Witt hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .304 with two doubles, a home run and four RBIs.
• Maikel Garcia leads Kansas City in OBP (.354) this season, fueled by 166 hits. He's batting .288 while slugging .455.
• Among all qualified batters, he is 16th in batting average, 32nd in on-base percentage and 55th in slugging percentage.
• Garcia has picked up at least one hit in two games in a row. In his last five games he is batting .278 with two doubles, three walks and two RBIs.
• Vinnie Pasquantino has 161 hits this season and has a slash line of .269/.328/.479.
• Salvador Perez has 30 home runs, 97 RBI and a batting average of .242 this season.
• Perez enters this game on a nine-game hitting streak. During his last 10 games he is hitting .342 with five home runs, three walks and 16 RBIs.

Angels Player Leaders

• Taylor Ward has a .474 slugging percentage, which leads the Angels. He's batting .228 with an on-base percentage of .315.
• Including all the qualified hitters in the majors, his batting average ranks 136th, his on-base percentage ranks 100th, and he is 36th in slugging.
• Ward takes a six-game hitting streak into this matchup. In his last 10 outings he is batting .256 with five home runs and five RBIs.
• Jo Adell paces his team with 120 hits. He has a batting average of .237 while slugging .488 with an on-base percentage of .296.
• Including all qualified players, he is 118th in batting average, 125th in on-base percentage and 22nd in slugging percentage.
• Nolan Schanuel has an on-base percentage of .357, a team-best for the Angels.
• Mike Trout has 14 doubles, a triple, 22 home runs and 86 walks while batting .227.

Royals vs Angels Head to Head

• 9/23/2025: 8-4 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/10/2024: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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