Angels vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 24

Odds updated as of 5:13 a.m.

The Los Angeles Angels will face the Kansas City Royals in MLB action on Wednesday.

All the info you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Angels vs Royals Game Info

• Los Angeles Angels (70-87) vs. Kansas City Royals (79-78)
• Date: Wednesday, September 24, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and FDSKC

Angels vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-124) | KC: (+106)
• Spread: LAA: -1.5 (+158) | KC: +1.5 (-192)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Angels vs Royals Probable Starting Pitchers

Probable Pitchers: Yusei Kikuchi (Angels) - 6-11, 4.05 ERA vs Stephen Kolek (Royals) - 5-6, 3.54 ERA

This contest's pitching matchup is set, as the Angels will send Yusei Kikuchi (6-11) to the mound, while Stephen Kolek (5-6) will answer the bell for the Royals. Kikuchi and his team have a record of 17-15-0 against the spread when he starts. Kikuchi's team has won 72.7% of his starts when they are favored on the moneyline (8-3). The Royals have a 12-6-0 record against the spread in Kolek's starts. The Royals are 4-7 in Kolek's 11 starts this season that they were the moneyline underdog.

Angels vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (52.6%)

Angels vs Royals Moneyline

• Los Angeles is a -124 favorite on the moneyline, while Kansas City is a +106 underdog on the road.

Angels vs Royals Spread

• The Angels are 1.5-run home favorites on the runline against the Royals. The Angels are +158 to cover, and the Royals are -192.

Angels vs Royals Over/Under

• Angels versus Royals on Sept. 24 has an over/under of 8.5 runs, with the odds on the over -100 and the under set at -122.

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Angels vs Royals Betting Trends

• The Angels have come away with 18 wins in the 36 contests they have been listed as the favorites in this season.
• This season Los Angeles has come away with a win 14 times in 27 chances when named as a favorite of at least -124 on the moneyline.
• Contests with the Angels have gone over the total set by sportsbooks in 83 of 155 chances this season.
• The Angels have an against the spread mark of 81-74-0 in 155 games with a line this season.
• The Royals have put together a 41-50 record in games they were listed as the moneyline underdog (winning 45.1% of those games).
• When playing as a moneyline underdog with odds of +106 or longer, Kansas City has a 25-36 record (winning 41% of its games).
• The Royals have combined with opponents to hit the over on the total 68 times this season for a 68-85-2 record against the over/under.
• The Royals have covered 49% of their games this season, going 76-79-0 ATS.

Angels Player Leaders

• Taylor Ward leads Los Angeles with a slugging percentage of .474, fueled by 68 extra-base hits. He has a .228 batting average and an on-base percentage of .315.
• Among qualified hitters in baseball, his batting average ranks 136th, his on-base percentage ranks 100th, and he is 35th in slugging.
• Ward hopes to build on a six-game hitting streak in this matchup. In his last 10 outings he is hitting .256 with five home runs and five RBIs.
• Jo Adell leads Los Angeles with 120 hits. He is batting .237 this season and has 54 extra-base hits. He's also slugging .488 with an on-base percentage of .296.
• Among all qualifying hitters, he is 118th in batting average, 125th in on-base percentage and 22nd in slugging percentage.
• Adell takes a two-game streak with at least one hit into this matchup. In his last five games he is batting .222 with two walks and an RBI.
• Nolan Schanuel leads Los Angeles with an OBP of .357 this season while batting .268 with 58 walks and 63 runs scored.
• Schanuel takes a four-game hitting streak into this matchup. In his last five games he is hitting .294 with a double, a home run, two walks and three RBIs.
• Mike Trout has been key for Los Angeles with 101 hits, an OBP of .356 plus a slugging percentage of .412.

Royals Player Leaders

• Bobby Witt Jr. has a slugging percentage of .502 and has 176 hits, both team-high numbers for the Royals. He's batting .293 and with an on-base percentage of .351.
• Including all qualifying hitters, he is 11th in batting average, while his on-base percentage is 35th and he is 16th in slugging.
• Witt brings a four-game hitting streak into this game. In his last five games he is batting .304 with two doubles, a home run and four RBIs.
• Maikel Garcia has a .354 OBP to lead his team. He has a batting average of .288 while slugging .455.
• He is currently 16th in batting average, 32nd in on-base percentage and 56th in slugging percentage among all qualifying batters.
• Vinnie Pasquantino is hitting .269 with 31 doubles, a triple, 31 home runs and 48 walks.
• Salvador Perez has 34 doubles, 30 home runs and 26 walks while hitting .242.

Angels vs Royals Head to Head

• 9/23/2025: 8-4 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 5/10/2024: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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