Diamondbacks vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 7:13 p.m.

In MLB action on Saturday, the Philadelphia Phillies play the Arizona Diamondbacks.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Phillies vs Diamondbacks Game Info

• Philadelphia Phillies (92-62) vs. Arizona Diamondbacks (77-77)
• Date: Saturday, September 20, 2025
• Time: 8:10 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: ARID and NBCS-PH

Phillies vs Diamondbacks Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-134) | ARI: (+114)
• Spread: PHI: -1.5 (+114) | ARI: +1.5 (-137)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Phillies vs Diamondbacks Probable Starting Pitchers

Probable Pitchers: Aaron Nola (Phillies) - 4-9, 6.44 ERA vs Zac Gallen (Diamondbacks) - 12-14, 4.73 ERA

This contest's pitching matchup is set, as the Phillies will send Aaron Nola (4-9) to the mound, while Zac Gallen (12-14) will get the nod for the Diamondbacks. When Nola starts, his team is 7-8-0 against the spread this season. Nola's team has been victorious in 36.4% of the games he's started as the moneyline favorite with a record of 4-7. The Diamondbacks have a 14-17-0 ATS record in Gallen's 31 starts that had a set spread. The Diamondbacks have been the moneyline underdog in 13 of Gallen's starts this season, and they went 7-6 in those matchups.

Phillies vs Diamondbacks Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (52.6%)

Phillies vs Diamondbacks Moneyline

• The Phillies vs Diamondbacks moneyline has Philadelphia as a -134 favorite, while Arizona is a +114 underdog at home.

Phillies vs Diamondbacks Spread

• The Diamondbacks are hosting the Phillies, and are +1.5 on the runline. The Diamondbacks are +114 to cover the spread, and the Phillies are -137.

Phillies vs Diamondbacks Over/Under

• A total of 8.5 runs has been set for the Phillies-Diamondbacks game on Sept. 20, with the over available at -122 and the under at -100.

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Phillies vs Diamondbacks Betting Trends

• The Phillies have been victorious in 75, or 65.2%, of the 115 contests they have been chosen as favorites in this season.
• Philadelphia has a record of 60-28 when favored by -134 or more this year.
• The Phillies and their opponents have gone over in 62 of their 147 games with a total set by sportsbooks this season.
• The Phillies have posted a record of 77-70-0 against the spread this season.
• The Diamondbacks have won 49.2% of the games this season they were the moneyline underdog (31-32).
• In games it has played as a moneyline underdog with odds of +114 or longer, Arizona has a 17-15 record (winning 53.1% of its games).
• The Diamondbacks have played in 150 games with an over/under set, and have combined with opponents to go over the total 75 times (75-68-7).
• The Diamondbacks have a 74-76-0 record ATS this season.

Phillies Player Leaders

• Kyle Schwarber has 138 hits and an OBP of .369, both of which lead Philadelphia hitters this season. He has a .241 batting average and a slugging percentage of .563.
• Among qualified batters in MLB, he ranks 110th in batting average, 12th in on-base percentage, and fourth in slugging.
• Bryce Harper has 32 doubles, 27 home runs and 68 walks. He's batting .266 and slugging .502 with an on-base percentage of .362.
• He ranks 47th in batting average, 16th in on-base percentage and 16th in slugging among qualified hitters.
• Bryson Stott has 120 hits this season and has a slash line of .254/.327/.386.
• Nick Castellanos is batting .255 with a .299 OBP and 69 RBI for Philadelphia this season.
• Castellanos enters this game on a two-game hitting streak. During his last five outings he is hitting .231 with a home run, a walk and four RBIs.

Diamondbacks Player Leaders

• Geraldo Perdomo has racked up a team-best OBP (.391) and slugging percentage (.461). He's batting .289.
• Including all qualified hitters, he is 13th in batting average, while his on-base percentage ranks fifth and he is 48th in slugging.
• Perdomo hopes to build on a nine-game hitting streak in this matchup. During his last 10 games he is batting .361 with three doubles, a triple, two home runs, eight walks and six RBIs.
• Corbin Carroll's 140 hits lead his team. He has a batting average of .259 while slugging .543 with an on-base percentage of .340.
• He is currently 68th in batting average, 52nd in on-base percentage and sixth in slugging percentage among all qualified batters.
• Ketel Marte is batting .279 with 25 doubles, 26 home runs and 63 walks.
• Gabriel Moreno is batting .285 with 12 doubles, a triple, nine home runs and 25 walks.

Phillies vs Diamondbacks Head to Head

• 9/19/2025: 8-2 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/4/2025: 11-9 ARI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/3/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/2/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 12-5 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/10/2024: 11-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 3-2 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/8/2024: 6-4 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/23/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 6/22/2024: 12-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -270, Underdog Moneyline: +220)

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