Diamondbacks vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 5:14 a.m.

Saturday's slate in the MLB includes a matchup between the Arizona Diamondbacks and the Philadelphia Phillies.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Phillies Game Info

• Arizona Diamondbacks (77-77) vs. Philadelphia Phillies (92-62)
• Date: Saturday, September 20, 2025
• Time: 8:10 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: ARID and NBCS-PH

Diamondbacks vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-112) | PHI: (-104)
• Spread: ARI: +1.5 (-178) | PHI: -1.5 (+146)
• Total: 9 -- Over: (-110) | Under: (-110)

Diamondbacks vs Phillies Probable Starting Pitchers

Probable Pitchers: Zac Gallen (Diamondbacks) - 12-14, 4.73 ERA vs Aaron Nola (Phillies) - 4-9, 6.44 ERA

The Diamondbacks will give the nod to Zac Gallen (12-14, 4.73 ERA), who is eyeing win No. 13 on the season, and the Phillies will counter with Aaron Nola (4-9, 6.44 ERA). Gallen and his team have a record of 14-17-0 against the spread when he starts. Gallen's team is 8-10 this season when he starts and they are the moneyline favorite. When Nola starts, the Phillies have gone 7-8-0 against the spread. The Phillies are 2-2 in Nola's four starts this season that they were the moneyline underdog.

Diamondbacks vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (53.5%)

Diamondbacks vs Phillies Moneyline

• Philadelphia is the underdog, -104 on the moneyline, while Arizona is a -112 favorite at home.

Diamondbacks vs Phillies Spread

• The Phillies are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Phillies are +146 to cover, while the Diamondbacks are -178 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Phillies Over/Under

• A total of 9 runs has been set for the Diamondbacks-Phillies contest on Sept. 20, with the over available at -110 and the under at -110.

Bet on Arizona Diamondbacks vs. Philadelphia Phillies on FanDuel today!

Diamondbacks vs Phillies Betting Trends

• The Diamondbacks have come away with 44 wins in the 84 contests they have been listed as the favorites in this season.
• Arizona has a record of 41-40 when favored by -112 or more this year.
• The Diamondbacks and their opponents have gone over in 75 of their 150 games with a total set by sportsbooks this season.
• In 150 games with a line this season, the Diamondbacks have a mark of 74-76-0 against the spread.
• The Phillies are 14-15 in games they were listed as the moneyline underdog (winning 48.3% of those games).
• Philadelphia has a 14-13 record (winning 51.9% of its games) when playing as a moneyline underdog of -104 or longer.
• The Phillies have played in 147 games with an over/under set, and have combined with their opponents to go over the total 62 times (62-76-9).
• The Phillies have a 77-70-0 record against the spread this season.

Diamondbacks Player Leaders

• Geraldo Perdomo has an OPS of .852, fueled by an OBP of .391 to go with a slugging percentage of .461. He has a .289 batting average, as well.
• Among qualifying hitters, he is 13th in batting average, his on-base percentage ranks fifth, and he is 49th in slugging.
• Perdomo has hit safely in nine games in a row. During his last 10 outings he is hitting .361 with three doubles, a triple, two home runs, eight walks and six RBIs.
• Corbin Carroll leads Arizona with 140 hits. He is batting .259 this season and has 77 extra-base hits. He's also slugging .543 with an on-base percentage of .340.
• Among all qualified hitters, he ranks 69th in batting average, 52nd in on-base percentage and seventh in slugging percentage.
• Carroll brings a five-game streak with at least one hit into this matchup. During his last five outings he is batting .368 with a double, a triple, three walks and two RBIs.
• Ketel Marte has 126 hits this season and has a slash line of .279/.375/.508.
• Gabriel Moreno is batting .285 with a .351 OBP and 37 RBI for Arizona this season.

Phillies Player Leaders

• Kyle Schwarber has totaled 138 hits with a .369 on-base percentage, leading the Phillies in both statistics. He's batting .241 and slugging .563.
• Including all qualified hitters in MLB, he ranks 110th in batting average, 12th in on-base percentage and fourth in slugging percentage.
• Bryce Harper has 32 doubles, 27 home runs and 68 walks while batting .266. He's slugging .502 with an on-base percentage of .362.
• His batting average ranks 48th among all qualified players, his on-base percentage ranks 15th, and he is 16th in slugging.
• Bryson Stott is batting .254 with 20 doubles, three triples, 12 home runs and 52 walks.
• Nick Castellanos is batting .255 with 27 doubles, two triples, 17 home runs and 31 walks.

Diamondbacks vs Phillies Head to Head

• 9/19/2025: 8-2 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/4/2025: 11-9 ARI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/3/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/2/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 12-5 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/10/2024: 11-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 3-2 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/8/2024: 6-4 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/23/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 6/22/2024: 12-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -270, Underdog Moneyline: +220)

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