Top 25 College Basketball Picks & Predictions Today - February 28

There are 15 games on Saturday's slate that involve teams ranked in the Top 25 in the AP Poll, highlighted by a game that has No. 1 Duke squaring off against No. 11 Virginia (at 12 p.m. ET). In the article below, we provide our picks and predictions for each matchup.

Check out our betting preview for college basketball's action today.

Duke vs. Virginia

• Matchup: No. 11 Virginia Cavaliers at No. 1 Duke Blue Devils
• Projected Winner: Duke (69.26% win probability)
• Spread: Duke (-10.5)
• Time: 12 p.m. ET
• Date: February 28
• TV Channel: ESPN

Bet on Duke vs. Virginia with FanDuel Sportsbook.

UConn vs. Seton Hall

• Matchup: Seton Hall Pirates at No. 6 UConn Huskies
• Projected Winner: UConn (80.81% win probability)
• Spread: UConn (-13.5)
• Time: 12 p.m. ET
• Date: February 28
• TV Channel: Fox Sports 1

Bet on UConn vs. Seton Hall with FanDuel Sportsbook.

Houston vs. Colorado

• Matchup: Colorado Buffaloes at No. 5 Houston Cougars
• Projected Winner: Houston (88.69% win probability)
• Spread: Houston (-18.5)
• Time: 12 p.m. ET
• Date: February 28
• TV Channel: ESPN2

Bet on Houston vs. Colorado with FanDuel Sportsbook.

Clemson vs. Louisville

• Matchup: No. 24 Louisville Cardinals at Clemson Tigers
• Projected Winner: Clemson (60.15% win probability)
• Spread: Louisville (-1.5)
• Time: 2 p.m. ET
• Date: February 28
• TV Channel: ESPN2

Bet on Clemson vs. Louisville with FanDuel Sportsbook.

Kentucky vs. Vanderbilt

• Matchup: No. 25 Vanderbilt Commodores at Kentucky Wildcats
• Projected Winner: Kentucky (53.61% win probability)
• Spread: Kentucky (-1.5)
• Time: 2 p.m. ET
• Date: February 28
• TV Channel: ESPN

Bet on Kentucky vs. Vanderbilt with FanDuel Sportsbook.

USC vs. Nebraska

• Matchup: No. 12 Nebraska Cornhuskers at USC Trojans
• Projected Winner: Nebraska (64.81% win probability)
• Spread: Nebraska (-3.5)
• Time: 4 p.m. ET
• Date: February 28
• TV Channel: BTN

Bet on USC vs. Nebraska with FanDuel Sportsbook.

Iowa State vs. Texas Tech

• Matchup: No. 16 Texas Tech Red Raiders at No. 4 Iowa State Cyclones
• Projected Winner: Iowa State (73.20% win probability)
• Spread: Iowa State (-9.5)
• Time: 4 p.m. ET
• Date: February 28
• TV Channel: CBS

Bet on Iowa State vs. Texas Tech with FanDuel Sportsbook.

Arizona vs. Kansas

• Matchup: No. 14 Kansas Jayhawks at No. 2 Arizona Wildcats
• Projected Winner: Arizona (77.35% win probability)
• Spread: Arizona (-9.5)
• Time: 4 p.m. ET
• Date: February 28
• TV Channel: ESPN

Bet on Arizona vs. Kansas with FanDuel Sportsbook.

West Virginia vs. BYU

• Matchup: No. 19 BYU Cougars at West Virginia Mountaineers
• Projected Winner: BYU (50.22% win probability)
• Spread: BYU (-2.5)
• Time: 5:30 p.m. ET
• Date: February 28
• TV Channel: FOX

Bet on West Virginia vs. BYU with FanDuel Sportsbook.

Tennessee vs. Alabama

• Matchup: No. 17 Alabama Crimson Tide at No. 22 Tennessee Volunteers
• Projected Winner: Tennessee (70.56% win probability)
• Spread: Tennessee (-4.5)
• Time: 6 p.m. ET
• Date: February 28
• TV Channel: ESPN

Bet on Tennessee vs. Alabama with FanDuel Sportsbook.

St. John's vs. Villanova

• Matchup: Villanova Wildcats at No. 15 St. John's Red Storm
• Projected Winner: St. John's (67.75% win probability)
• Spread: St. John's (-7.5)
• Time: 8 p.m. ET
• Date: March 1
• TV Channel: FOX

Bet on St. John's vs. Villanova with FanDuel Sportsbook.

Saint Louis vs. Duquesne

• Matchup: Duquesne Dukes at No. 23 Saint Louis Billikens
• Projected Winner: Saint Louis (92.69% win probability)
• Spread: Saint Louis (-15.5)
• Time: 8 p.m. ET
• Date: March 1
• TV Channel: ESPN+

Bet on Saint Louis vs. Duquesne with FanDuel Sportsbook.

Florida vs. Arkansas

• Matchup: No. 20 Arkansas Razorbacks at No. 7 Florida Gators
• Projected Winner: Florida (77.36% win probability)
• Spread: Florida (-9.5)
• Time: 8:30 p.m. ET
• Date: March 1
• TV Channel: ESPN

Bet on Florida vs. Arkansas with FanDuel Sportsbook.

North Carolina vs. Virginia Tech

• Matchup: Virginia Tech Hokies at No. 18 North Carolina Tar Heels
• Projected Winner: North Carolina (76.02% win probability)
• Spread: North Carolina (-6.5)
• Time: 8:30 p.m. ET
• Date: March 1
• TV Channel: ESPN2

Bet on North Carolina vs. Virginia Tech with FanDuel Sportsbook.

Saint Mary's (CA) vs. Gonzaga

• Matchup: No. 9 Gonzaga Bulldogs at Saint Mary's Gaels
• Projected Winner: Saint Mary's (CA) (65.31% win probability)
• Spread: Gonzaga (-2.5)
• Time: 10:30 p.m. ET
• Date: March 1
• TV Channel: ESPN

Bet on Saint Mary's (CA) vs. Gonzaga with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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