Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 28

Odds updated as of 10:12 p.m.

On Sunday in MLB, the Milwaukee Brewers are up against the Cincinnati Reds.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Reds Game Info

• Milwaukee Brewers (96-64) vs. Cincinnati Reds (82-78)
• Date: Sunday, September 28, 2025
• Time: 3:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and FDSOH

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-130) | CIN: (+110)
• Spread: MIL: -1.5 (+164) | CIN: +1.5 (-200)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Freddy Peralta (Brewers) - 17-6, 2.68 ERA vs Brady Singer (Reds) - 14-11, 3.95 ERA

This contest's pitching matchup is set, as the Brewers will send Freddy Peralta (17-6) to the mound, while Brady Singer (14-11) will take the ball for the Reds. Peralta and his team are 18-14-0 ATS this season when he starts. Peralta's team has a record of 13-8 this season when he starts and they are the favorite on the moneyline. The Reds have a 17-12-0 record against the spread in Singer's starts. The Reds are 10-5 in Singer's 15 starts this season that they were the underdog on the moneyline.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (57.5%)

Brewers vs Reds Moneyline

• Milwaukee is the favorite, -130 on the moneyline, while Cincinnati is a +110 underdog on the road.

Brewers vs Reds Spread

• The Reds are at +1.5 on the runline against the Brewers. The Reds are -200 to cover the spread, and the Brewers are +164.

Brewers vs Reds Over/Under

• The over/under for Brewers-Reds on Sept. 28 is 7.5. The over is -115, and the under is -105.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have been favorites in 94 games this season and have come away with the win 59 times (62.8%) in those contests.
• Milwaukee has a record of 44-17 in contests when oddsmakers favor them by -130 or more on the moneyline.
• The Brewers and their opponents have gone over in 78 of their 157 games with a total set by sportsbooks this season.
• The Brewers have posted a record of 86-71-0 against the spread this season.
• The Reds have been the moneyline underdog 83 total times this season. They've gone 41-42 in those games.
• When it has played as a moneyline underdog with odds of +110 or longer, Cincinnati has gone 20-30 (40%).
• In the 151 games bookmakers have set an over/under for the Reds, they have combined with opponents to go over the total 58 times (58-83-10).
• The Reds have collected a 79-72-0 record against the spread this season (covering 52.3% of the time).

Brewers Player Leaders

• Brice Turang leads Milwaukee OPS (.789) this season. He has a .287 batting average, an on-base percentage of .356, and a slugging percentage of .433.
• Among all qualified hitters in baseball, he is 17th in batting average, 25th in on-base percentage, and 73rd in slugging.
• Turang hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .313 with two walks and two RBIs.
• Christian Yelich is batting .265 with 21 doubles, 29 home runs and 63 walks, while slugging .457 with an on-base percentage of .344.
• Among qualified hitters, his batting average ranks him 47th, his on-base percentage 47th, and his slugging percentage 51st.
• Yelich has picked up a hit in four games in a row. During his last five outings he is hitting .235 with a double, three walks and two RBIs.
• William Contreras has collected 147 base hits, an OBP of .355 and a slugging percentage of .399 this season.
• Jackson Chourio has 145 hits, which leads Milwaukee hitters this season, while batting .269 with 58 extra-base hits.

Reds Player Leaders

• Elly De La Cruz has put up a team-high slugging percentage (.438) and paces the Reds in hits (164). He's batting .264 and with an on-base percentage of .336.
• Including all qualified players, he is 53rd in batting average, while his on-base percentage is 56th and he is 66th in slugging.
• TJ Friedl leads his team with a .365 on-base percentage. He has a batting average of .261 while slugging .375.
• Including all qualifying hitters, he is 65th in batting average, 15th in on-base percentage and 130th in slugging percentage.
• Spencer Steer has 20 doubles, two triples, 21 home runs and 48 walks while hitting .239.
• Austin Hays is hitting .266 with 16 doubles, five triples, 15 home runs and 29 walks.

Brewers vs Reds Head to Head

• 9/26/2025: 3-1 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/17/2025: 3-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/16/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/15/2025: 10-8 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/4/2025: 9-1 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/3/2025: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/2/2025: 3-2 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/6/2025: 8-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 11-7 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/4/2025: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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