Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 28

Odds updated as of 2:14 p.m.

The MLB's Sunday schedule includes the Milwaukee Brewers facing the Cincinnati Reds.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Reds Game Info

• Milwaukee Brewers (96-65) vs. Cincinnati Reds (83-78)
• Date: Sunday, September 28, 2025
• Time: 3:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and FDSOH

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-130) | CIN: (+110)
• Spread: MIL: -1.5 (+146) | CIN: +1.5 (-178)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Freddy Peralta (Brewers) - 17-6, 2.68 ERA vs Brady Singer (Reds) - 14-11, 3.95 ERA

The Brewers will call on Freddy Peralta (17-6) versus the Reds and Brady Singer (14-11). When Peralta starts, his team is 18-14-0 against the spread this season. Peralta's team is 13-8 this season when he starts and they are the moneyline favorite. The Reds have a 17-12-0 record against the spread in Singer's starts. The Reds have a 10-5 record in Singer's 15 starts this season when they were the moneyline underdog.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (57.1%)

Brewers vs Reds Moneyline

• Milwaukee is the favorite, -130 on the moneyline, while Cincinnati is a +110 underdog on the road.

Brewers vs Reds Spread

• The Brewers are hosting the Reds and are favored by 1.5 runs on the spread. The Brewers are +146 to cover the runline, with the Reds being -178.

Brewers vs Reds Over/Under

• The Brewers-Reds game on Sept. 28 has been given an over/under of 7.5 runs. The over is set at -115 and the under at -105.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have been chosen as favorites in 95 games this year and have walked away with the win 59 times (62.1%) in those games.
• This season Milwaukee has been victorious 44 times in 62 chances when named as a favorite of at least -130 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 79 of their 158 opportunities.
• The Brewers have an against the spread mark of 86-72-0 in 158 games with a line this season.
• The Reds have won 50% of the games this season they were the moneyline underdog (42-42).
• When it has played as a moneyline underdog with odds of +110 or longer, Cincinnati has gone 21-30 (41.2%).
• The Reds have played in 152 games with a set over/under, and have combined with opponents to go over the total 59 times (59-83-10).
• The Reds have an 80-72-0 record ATS this season (covering 52.6% of the time).

Brewers Player Leaders

• Brice Turang leads Milwaukee with an OBP of .357, plus a team-best slugging percentage of .434. He's batting .287 on the season.
• Among all qualified batters in baseball, his batting average ranks 17th, his on-base percentage ranks 23rd, and he is 71st in slugging.
• Turang has hit safely in three games in a row. In his last five games he is batting .333 with a double, three walks and three RBIs.
• Christian Yelich is hitting .265 with 21 doubles, 29 home runs and 63 walks, while slugging .454 with an on-base percentage of .343.
• He ranks 47th in batting average, 50th in on-base percentage and 53rd in slugging among qualifying batters.
• Yelich has picked up at least one hit in five games in a row. During his last five outings he is hitting .238 with a double, three walks and three RBIs.
• William Contreras has 147 hits this season and has a slash line of .260/.355/.399.
• Jackson Chourio leads Milwaukee with 146 hits, batting .268 this season with 59 extra-base hits.

Reds Player Leaders

• Elly De La Cruz has put up a slugging percentage of .437 and has 165 hits, both team-best figures for the Reds. He's batting .264 and with an on-base percentage of .337.
• Including all qualified players in MLB, he is 54th in batting average, 56th in on-base percentage and 66th in slugging percentage.
• TJ Friedl leads his team with a .363 on-base percentage. He has a batting average of .260 while slugging .373.
• His batting average ranks 66th among all qualified players, his on-base percentage ranks 17th, and he is 131st in slugging.
• Spencer Steer has 20 doubles, two triples, 21 home runs and 50 walks while batting .237.
• Austin Hays is batting .266 with 16 doubles, five triples, 15 home runs and 29 walks.

Brewers vs Reds Head to Head

• 9/27/2025: 7-4 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/26/2025: 3-1 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/17/2025: 3-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/16/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/15/2025: 10-8 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/4/2025: 9-1 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/3/2025: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/2/2025: 3-2 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/6/2025: 8-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 11-7 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)

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