Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 4:13 a.m.

MLB action on Saturday includes the Milwaukee Brewers playing the Cincinnati Reds.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Brewers vs Reds Game Info

• Milwaukee Brewers (96-64) vs. Cincinnati Reds (82-78)
• Date: Saturday, September 27, 2025
• Time: 7:15 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FOX

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-152) | CIN: (+128)
• Spread: MIL: -1.5 (+146) | CIN: +1.5 (-178)
• Total: 7.5 -- Over: (-120) | Under: (-102)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Robert Gasser (Brewers) - 0-1, 6.00 ERA vs Andrew Abbott (Reds) - 9-7, 2.80 ERA

This contest's pitching matchup is set, as the Brewers will send Robert Gasser (0-1) to the mound, while Andrew Abbott (9-7) will answer the bell for the Reds. Gasser and his team failed to cover the spread in his only opportunity this season as a starter. Gasser's team lost his only start as a favorite this season. The Reds have a 14-12-0 ATS record in Abbott's 26 starts that had a set spread. The Reds have been the underdog on the moneyline in 10 of Abbott's starts this season, and they went 6-4 in those games.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (52.8%)

Brewers vs Reds Moneyline

• Looking at the moneyline for Reds-Brewers, Cincinnati is the underdog at +128, and Milwaukee is -152 playing at home.

Brewers vs Reds Spread

• The Brewers are hosting the Reds and are favored by 1.5 runs (+146 to cover) on the runline. Cincinnati is -178 to cover.

Brewers vs Reds Over/Under

• A combined run total of 7.5 has been set for Brewers-Reds on Sept. 27, with the over at -120 and the under at -102.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have won in 59, or 62.8%, of the 94 contests they have been named as odds-on favorites in this year.
• This season Milwaukee has been victorious 28 times in 38 chances when named as a favorite of at least -152 on the moneyline.
• The Brewers and their opponents have gone over in 78 of their 157 games with a total set by sportsbooks this season.
• The Brewers are 86-71-0 against the spread in their 157 games that had a posted line this season.
• The Reds have gone 41-42 in games they were the underdog on the moneyline (winning 49.4% of those games).
• When it has played as a moneyline underdog with odds of +128 or longer, Cincinnati has a 16-15 record (winning 51.6% of its games).
• The Reds have played in 151 games with an over/under set, and have combined with opponents to go over the total 58 times (58-83-10).
• The Reds have gone 79-72-0 against the spread this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee OPS (.789) this season. He has a .287 batting average, an on-base percentage of .356, and a slugging percentage of .433.
• Among all qualified batters, he ranks 17th in batting average, his on-base percentage ranks 26th, and he is 73rd in slugging.
• Turang has recorded at least one hit in two straight games. In his last five games he is hitting .313 with two walks and two RBIs.
• Christian Yelich is hitting .265 with 21 doubles, 29 home runs and 63 walks, while slugging .457 with an on-base percentage of .344.
• Among qualifiers, he ranks 49th in batting average, 48th in on-base percentage and 53rd in slugging percentage.
• Yelich has picked up at least one hit in four straight games. During his last five outings he is batting .235 with a double, three walks and two RBIs.
• William Contreras has 147 hits this season and has a slash line of .260/.355/.399.
• Jackson Chourio leads Milwaukee with 145 hits, batting .269 this season with 58 extra-base hits.

Reds Player Leaders

• Elly De La Cruz has racked up a team-best slugging percentage (.438) and paces the Reds in hits (164). He's batting .264 and with an on-base percentage of .336.
• Including all qualifying hitters, he is 54th in batting average, while his on-base percentage is 58th and he is 69th in slugging.
• TJ Friedl leads his team with a .365 on-base percentage. He has a batting average of .261 while slugging .375.
• Including all qualifying players, he is 65th in batting average, 14th in on-base percentage and 130th in slugging percentage.
• Spencer Steer has 20 doubles, two triples, 21 home runs and 48 walks while hitting .239.
• Austin Hays has 16 doubles, five triples, 15 home runs and 29 walks while batting .266.

Brewers vs Reds Head to Head

• 9/26/2025: 3-1 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/17/2025: 3-2 CIN (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/16/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/15/2025: 10-8 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/4/2025: 9-1 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/3/2025: 4-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 6/2/2025: 3-2 MIL (Favorite: Reds, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/6/2025: 8-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 11-7 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/4/2025: 3-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)

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