Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 2 on Oct. 6

Odds updated as of 6:13 a.m.

The MLB slate on Monday includes the Milwaukee Brewers taking on the Chicago Cubs in Game 2 of the NLDS.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this game.

Brewers vs Cubs Game Info

• Milwaukee Brewers (97-65) vs. Chicago Cubs (92-70)
• Date: Monday, October 6, 2025
• Time: 9:08 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: TBS, truTV, and HBO Max

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-120) | CHC: (+102)
• Spread: MIL: -1.5 (+176) | CHC: +1.5 (-215)
• Total: 8 -- Over: (-105) | Under: (-115)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Aaron Ashby (Brewers) - 5-2, 2.16 ERA vs Shota Imanaga (Cubs) - 9-8, 3.73 ERA

The Brewers will give the nod to Aaron Ashby (5-2, 2.16 ERA) versus the Cubs and Shota Imanaga (9-8, 3.73 ERA). Ashby and his team failed to cover the spread in his only opportunity this season as a starter. Ashby's team lost his only start as a favorite this season. When Imanaga starts, the Cubs are 9-15-0 against the spread. The Cubs have been the moneyline underdog in eight of Imanaga's starts this season, and they went 4-4 in those games.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (50.2%)

Brewers vs Cubs Moneyline

• Milwaukee is the favorite, -120 on the moneyline, while Chicago is a +102 underdog on the road.

Brewers vs Cubs Spread

• The Cubs are +1.5 on the spread (-215 to cover), and Milwaukee is +176 to cover the runline.

Brewers vs Cubs Over/Under

• An over/under of 8 has been set for Brewers-Cubs on Oct. 6, with the over being -105 and the under -115.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have won in 61, or 62.9%, of the 97 contests they have been named as odds-on favorites in this year.
• This season Milwaukee has been victorious 52 times in 77 chances when named as a favorite of at least -120 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 80 of their 160 opportunities.
• The Brewers have posted a record of 88-72-0 against the spread this season.
• The Cubs have an 18-27 record in games they were listed as the moneyline underdog (winning 40% of those games).
• When it has played as a moneyline underdog with odds of +102 or longer, Chicago has gone 11-17 (39.3%).
• The Cubs have had an over/under set by bookmakers 161 times, and have combined with opponents to go over the total in 75 of those games (75-75-11).
• The Cubs have gone 77-84-0 ATS this season.

Brewers Player Leaders

• Brice Turang has an OPS of .794, fueled by an OBP of .359 to go with a slugging percentage of .435. He has a .288 batting average, as well.
• He ranks 16th in batting average, 20th in on-base percentage, and 71st in slugging among qualified hitters in the majors.
• Turang will look for his sixth straight game with a hit in this contest. During his last five outings he is hitting .421 with three doubles, three walks and five RBIs.
• Christian Yelich is batting .264 with 21 doubles, 29 home runs and 64 walks, while slugging .452 with an on-base percentage of .343.
• His batting average is 51st among qualified players, his on-base percentage 49th, and his slugging percentage 56th.
• William Contreras is batting .260 with a .399 slugging percentage and 76 RBI this year.
• Jackson Chourio has 148 hits, which is tops among Milwaukee hitters this season, while batting .270 with 60 extra-base hits.
• Chourio heads into this game on a three-game hitting streak. In his last five games he is batting .368 with two doubles, a home run, two walks and four RBIs.

Cubs Player Leaders

• Kyle Tucker has a team-high .377 on-base percentage. He's batting .266 and slugging .464.
• Including all the qualifying hitters in the big leagues, he is 46th in batting average, seventh in on-base percentage and 44th in slugging percentage.
• Nico Hoerner paces his team with a .394 slugging percentage. He has a batting average of .297 with an on-base percentage of .345.
• Including all qualifying hitters, he is eighth in batting average, 46th in on-base percentage and 110th in slugging percentage.
• Pete Crow-Armstrong has 37 doubles, four triples, 31 home runs and 29 walks while hitting .247.
• Seiya Suzuki is hitting .245 with 31 doubles, three triples, 32 home runs and 71 walks.

Brewers vs Cubs Head to Head

• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2025: 8-7 MIL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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