Blue Jays vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 28

Odds updated as of 2:11 a.m.

The Toronto Blue Jays will take on the Boston Red Sox in MLB action on Tuesday.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Blue Jays vs Red Sox Game Info

• Toronto Blue Jays (12-16) vs. Boston Red Sox (12-17)
• Date: Tuesday, April 28, 2026
• Time: 7:07 p.m. ET
• Venue: Rogers Centre -- Toronto, Ontario
• Coverage: SN1 and NESN+

Blue Jays vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-120) | BOS: (+102)
• Spread: TOR: +1.5 (-210) | BOS: -1.5 (+172)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Blue Jays vs Red Sox Probable Starting Pitchers

Probable Pitchers: Trey Yesavage (Blue Jays) - 0-0, 0.00 ERA vs Payton Tolle (Red Sox) - 0-0, 1.50 ERA

This contest's pitching matchup is set, as the Blue Jays will send Trey Yesavage to the mound, while Payton Tolle will get the nod for the Red Sox. Yesavage and his team were 6-2-0 against the spread when he pitched last season. Yesavage and his team won 80% of the games he started as the moneyline favorite last season, with a record of 4-1. Tolle has started only one game with a set spread, which the Red Sox failed to cover. The Red Sox were the underdog on the moneyline for one Tolle start this season -- they lost.

Blue Jays vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (56.5%)

Blue Jays vs Red Sox Moneyline

• Looking at the moneyline for Red Sox-Blue Jays, Boston is the underdog at +102, and Toronto is -120 playing at home.

Blue Jays vs Red Sox Spread

• The Red Sox are 1.5-run favorites against the spread for this matchup with the Blue Jays. The Red Sox are +172 to cover, while the Blue Jays are -210 to cover as a 1.5-run underdog on the runline.

Blue Jays vs Red Sox Over/Under

• The over/under for the Blue Jays versus Red Sox contest on April 28 has been set at 7.5, with -115 odds on the over and -105 odds on the under.

Bet on Toronto Blue Jays vs. Boston Red Sox on FanDuel today!

Blue Jays vs Red Sox Betting Trends

• The Blue Jays have been chosen as favorites in 18 games this year and have walked away with the win nine times (50%) in those games.
• This season Toronto has been victorious seven times in 16 chances when named as a favorite of at least -120 on the moneyline.
• The Blue Jays and their opponents have hit the over in 14 of their 28 games with a total set by oddsmakers this season.
• The Blue Jays have an against the spread record of 10-18-0 in 28 games with a line this season.
• The Red Sox have put together a 3-6 record in games they were listed as the moneyline underdog (winning 33.3% of those games).
• Boston has a 3-6 record (winning just 33.3% of its games) when playing as a moneyline underdog of +102 or longer.
• The Red Sox have had an over/under set by oddsmakers 29 times, and have combined with opponents to go over the total in 15 of those games (15-14-0).
• The Red Sox have a 10-19-0 record ATS this season.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. has 34 hits this season and a team-best OBP of .415. He has a .330 batting average and a slugging percentage of .447.
• Among qualified hitters in MLB, he ranks third in batting average, ninth in on-base percentage, and 63rd in slugging.
• Andres Gimenez leads Toronto in total hits (27) this season while batting .287 with 10 extra-base hits. He's slugging .468 with an on-base percentage of .313.
• He is 33rd in batting average, 119th in on-base percentage and 48th in slugging among qualified hitters.
• Gimenez has picked up at least one hit in three straight games. During his last five outings he is batting .353 with three doubles and four RBIs.
• Ernie Clement has hit zero homers with a team-high .422 SLG this season.
• Jesus Sanchez has four home runs, 15 RBI and a batting average of .268 this season.
• Sanchez enters this game on a two-game hitting streak. During his last five outings he is batting .286 with a double, two home runs and four RBIs.

Red Sox Player Leaders

• Wilyer Abreu has racked up a team-best slugging percentage (.491) while pacing the Red Sox in hits (33). He's batting .306 and with an on-base percentage of .364.
• Including all the qualified hitters in the majors, his batting average is 22nd, his on-base percentage is 37th, and he is 32nd in slugging.
• Abreu enters this game on a six-game hitting streak. In his last 10 games he is batting .289 with two doubles, a home run, five walks and three RBIs.
• Willson Contreras leads his team with a .375 OBP. He has a batting average of .253 while slugging .455.
• Including all qualified players, he is 75th in batting average, 24th in on-base percentage and 58th in slugging percentage.
• Caleb Durbin is batting .174 with six doubles, a home run and 10 walks.
• Ceddanne Rafaela has four doubles, two triples, a home run and six walks while hitting .275.

Blue Jays vs Red Sox Head to Head

• 4/27/2026: 5-0 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/25/2025: 6-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/24/2025: 7-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/23/2025: 4-1 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/29/2025: 5-3 TOR (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/28/2025: 15-1 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/27/2025: 9-0 TOR (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/1/2025: 4-2 TOR (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2025: 7-6 TOR (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/29/2025: 10-2 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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