Blue Jays vs Orioles Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 12

Odds updated as of 6:15 p.m.

The MLB slate on Friday includes the Toronto Blue Jays facing the Baltimore Orioles.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Blue Jays vs Orioles Game Info

• Toronto Blue Jays (84-62) vs. Baltimore Orioles (69-77)
• Date: Friday, September 12, 2025
• Time: 7:07 p.m. ET
• Venue: Rogers Centre -- Toronto, Ontario
• Coverage: SNET and MASN2

Blue Jays vs Orioles Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-136) | BAL: (+116)
• Spread: TOR: -1.5 (+146) | BAL: +1.5 (-178)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Blue Jays vs Orioles Probable Starting Pitchers

Probable Pitchers: Chris Bassitt (Blue Jays) - 11-8, 3.97 ERA vs Trevor Rogers (Orioles) - 8-2, 1.51 ERA

This contest's pitching matchup is set, as the Blue Jays will send Chris Bassitt (11-8) to the mound, while Trevor Rogers (8-2) will get the nod for the Orioles. When Bassitt starts, his team is 18-10-0 against the spread this season. Bassitt's team has a record of 8-7 this season when he starts and they are the favorite on the moneyline. The Orioles have gone 11-3-0 against the spread when Rogers starts. The Orioles are 6-2 in Rogers' eight starts this season that they were the moneyline underdog.

Blue Jays vs Orioles Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (55.4%)

Blue Jays vs Orioles Moneyline

• Looking at the moneyline for Orioles-Blue Jays, Baltimore is the underdog at +116, and Toronto is -136 playing at home.

Blue Jays vs Orioles Spread

• The Orioles are +1.5 on the run line against the Blue Jays. The Orioles are -178 to cover, and the Blue Jays are +146.

Blue Jays vs Orioles Over/Under

• A combined run total of 7.5 has been set for Blue Jays-Orioles on Sept. 12, with the over at -115 and the under at -105.

Bet on Toronto Blue Jays vs. Baltimore Orioles on FanDuel today!

Blue Jays vs Orioles Betting Trends

• The Blue Jays have been victorious in 40, or 58%, of the 69 contests they have been chosen as favorites in this season.
• This season Toronto has come away with a win 30 times in 45 chances when named as a favorite of at least -136 on the moneyline.
• Contests with the Blue Jays have gone over the total set by oddsmakers in 79 of 145 chances this season.
• The Blue Jays are 85-60-0 against the spread in their 145 games with a line set by sportsbooks this season.
• The Orioles have won 46.9% of the games this season they were the moneyline underdog (38-43).
• Baltimore is 18-23 (winning 43.9% of its games) when it has played as a moneyline underdog of +116 or longer.
• The Orioles have had an over/under set by bookmakers 143 times, and have combined with opponents to go over the total in 60 of those games (60-79-4).
• The Orioles have put together a 69-74-0 record ATS this season (covering 48.3% of the time).

Blue Jays Player Leaders

• Vladimir Guerrero Jr. leads Toronto with an OBP of .393 this season while batting .301 with 76 walks and 92 runs scored. He has a slugging percentage of .494.
• Among qualified hitters in MLB, his batting average ranks fifth, his on-base percentage ranks third, and he is 23rd in slugging.
• George Springer leads Toronto in total hits (129) this season while batting .297 with 50 extra-base hits. He's slugging .544 with an on-base percentage of .391.
• His batting average is seventh among qualified players, his on-base percentage fourth, and his slugging percentage seventh.
• Ernie Clement has collected 135 base hits, an OBP of .312 and a slugging percentage of .398 this season.
• Alejandro Kirk has 12 home runs, 65 RBI and a batting average of .289 this season.

Orioles Player Leaders

• Gunnar Henderson has accumulated a team-best OBP (.345) and slugging percentage (.442), while pacing the Orioles in hits (140, while batting .270).
• Including all the qualifying hitters in the majors, his batting average ranks 40th, his on-base percentage ranks 44th, and he is 68th in slugging.
• Jackson Holliday has 20 doubles, three triples, 17 home runs and 49 walks while batting .252. He's slugging .396 with an on-base percentage of .321.
• Including all qualified players, he ranks 91st in batting average, 94th in on-base percentage and 110th in slugging percentage.
• Ryan Mountcastle has 18 doubles, five home runs and 14 walks while batting .259.
• Colton Cowser is batting .206 with 12 doubles, 13 home runs and 22 walks.

Blue Jays vs Orioles Head to Head

• 7/30/2025: 9-8 TOR (Favorite: Orioles, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/29/2025: 3-2 BAL (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/29/2025: 16-4 BAL (Favorite: Orioles, Spread: -1.5, Total: 10, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 7/28/2025: 11-4 BAL (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/13/2025: 7-6 TOR (Favorite: Orioles, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 4/12/2025: 5-4 BAL (Favorite: Orioles, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/30/2025: 3-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 3/29/2025: 9-5 BAL (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/28/2025: 8-2 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 3/27/2025: 12-2 BAL (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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