Best College Football Games Week 10: Predictions, Odds, Picks, Best Bets

There are 17 games featuring a ranked team on the Week 10 college football schedule.

For a breakdown of all the important games in college football this week, dive into our betting preview below.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

Rice vs. Memphis

• Matchup: No. 25 Memphis Tigers at Rice Owls
• Projected Favorite: Memphis (74.56% win probability)
• Spread: Memphis (-13.5)
• Total: 48.5
• Time: 7 p.m. ET
• Date: Oct. 31
• TV Channel: ESPN2

Bet on Rice vs. Memphis with FanDuel Sportsbook.

Ohio State vs. Penn State

• Matchup: Penn State Nittany Lions at No. 1 Ohio State Buckeyes
• Projected Favorite: Ohio State (84.99% win probability)
• Spread: Ohio State (-18.5)
• Total: 44.5
• Time: 12 p.m. ET
• Date: Nov. 1
• TV Channel: FOX

Bet on Ohio State vs. Penn State with FanDuel Sportsbook.

Texas vs. Vanderbilt

• Matchup: No. 9 Vanderbilt Commodores at No. 20 Texas Longhorns
• Projected Favorite: Texas (57.51% win probability)
• Spread: Texas (-3.5)
• Total: 46.5
• Time: 12 p.m. ET
• Date: Nov. 1
• TV Channel: ABC

Bet on Texas vs. Vanderbilt with FanDuel Sportsbook.

SMU vs. Miami (FL)

• Matchup: No. 10 Miami (FL) Hurricanes at SMU Mustangs
• Projected Favorite: Miami (FL) (72.64% win probability)
• Spread: Miami (FL) (-10.5)
• Total: 50.5
• Time: 12 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN

Bet on SMU vs. Miami (FL) with FanDuel Sportsbook.

Houston vs. West Virginia

• Matchup: West Virginia Mountaineers at No. 22 Houston Cougars
• Projected Favorite: Houston (77.30% win probability)
• Spread: Houston (-12.5)
• Total: 48.5
• Time: 12 p.m. ET
• Date: Nov. 1
• TV Channel: Fox Sports 1

Bet on Houston vs. West Virginia with FanDuel Sportsbook.

Virginia Tech vs. Louisville

• Matchup: No. 16 Louisville Cardinals at Virginia Tech Hokies
• Projected Favorite: Louisville (81.00% win probability)
• Spread: Louisville (-10.5)
• Total: 52.5
• Time: 3 p.m. ET
• Date: Nov. 1
• TV Channel: The CW

Bet on Virginia Tech vs. Louisville with FanDuel Sportsbook.

Kansas State vs. Texas Tech

• Matchup: No. 13 Texas Tech Red Raiders at Kansas State Wildcats
• Projected Favorite: Texas Tech (66.79% win probability)
• Spread: Texas Tech (-7.5)
• Total: 51.5
• Time: 3:30 p.m. ET
• Date: Nov. 1
• TV Channel: FOX

Bet on Kansas State vs. Texas Tech with FanDuel Sportsbook.

Florida vs. Georgia

• Matchup: No. 5 Georgia Bulldogs vs. Florida Gators
• Projected Favorite: Georgia (68.18% win probability)
• Spread: Georgia (-7.5)
• Total: 50.5
• Time: 3:30 p.m. ET
• Date: Nov. 1
• TV Channel: ABC

Bet on Florida vs. Georgia with FanDuel Sportsbook.

Maryland vs. Indiana

• Matchup: No. 2 Indiana Hoosiers at Maryland Terrapins
• Projected Favorite: Indiana (94.32% win probability)
• Spread: Indiana (-20.5)
• Total: 50.5
• Time: 3:30 p.m. ET
• Date: Nov. 1
• TV Channel: CBS

Bet on Maryland vs. Indiana with FanDuel Sportsbook.

Boston College vs. Notre Dame

• Matchup: No. 12 Notre Dame Fighting Irish at Boston College Eagles
• Projected Favorite: Notre Dame (96.43% win probability)
• Spread: Notre Dame (-31.5)
• Total: 55.5
• Time: 3:30 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN

Bet on Boston College vs. Notre Dame with FanDuel Sportsbook.

California vs. Virginia

• Matchup: No. 15 Virginia Cavaliers at California Golden Bears
• Projected Favorite: Virginia (78.45% win probability)
• Spread: Virginia (-5.5)
• Total: 52.5
• Time: 3:45 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN2

Bet on California vs. Virginia with FanDuel Sportsbook.

Michigan vs. Purdue

• Matchup: Purdue Boilermakers at No. 21 Michigan Wolverines
• Projected Favorite: Michigan (95.50% win probability)
• Spread: Michigan (-21.5)
• Total: 48.5
• Time: 7 p.m. ET
• Date: Nov. 1
• TV Channel: BTN

Bet on Michigan vs. Purdue with FanDuel Sportsbook.

Ole Miss vs. South Carolina

• Matchup: South Carolina Gamecocks at No. 7 Ole Miss Rebels
• Projected Favorite: Ole Miss (72.46% win probability)
• Spread: Ole Miss (-12.5)
• Total: 55.5
• Time: 7 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN

Bet on Ole Miss vs. South Carolina with FanDuel Sportsbook.

Tennessee vs. Oklahoma

• Matchup: No. 18 Oklahoma Sooners at No. 14 Tennessee Volunteers
• Projected Favorite: Tennessee (59.89% win probability)
• Spread: Tennessee (-2.5)
• Total: 54.5
• Time: 7:30 p.m. ET
• Date: Nov. 1
• TV Channel: ABC

Bet on Tennessee vs. Oklahoma with FanDuel Sportsbook.

Nebraska vs. USC

• Matchup: No. 23 USC Trojans at Nebraska Cornhuskers
• Projected Favorite: USC (65.69% win probability)
• Spread: USC (-4.5)
• Total: 58.5
• Time: 7:30 p.m. ET
• Date: Nov. 1
• TV Channel: NBC

Bet on Nebraska vs. USC with FanDuel Sportsbook.

North Carolina State vs. Georgia Tech

• Matchup: No. 8 Georgia Tech Yellow Jackets at North Carolina State Wolfpack
• Projected Favorite: Georgia Tech (60.20% win probability)
• Spread: Georgia Tech (-4.5)
• Total: 58.5
• Time: 7:30 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN2

Bet on North Carolina State vs. Georgia Tech with FanDuel Sportsbook.

Utah vs. Cincinnati

• Matchup: No. 17 Cincinnati Bearcats at No. 24 Utah Utes
• Projected Favorite: Utah (73.53% win probability)
• Spread: Utah (-10.5)
• Total: 57.5
• Time: 10:15 p.m. ET
• Date: Nov. 1
• TV Channel: ESPN

Bet on Utah vs. Cincinnati with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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