Angels vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 10

Odds updated as of 3:12 p.m.

MLB action on Wednesday includes the Minnesota Twins taking on the Los Angeles Angels.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Twins vs Angels Game Info

• Minnesota Twins (64-81) vs. Los Angeles Angels (68-77)
• Date: Wednesday, September 10, 2025
• Time: 4:07 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and MNNT

Twins vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-118) | LAA: (-100)
• Spread: MIN: -1.5 (+138) | LAA: +1.5 (-166)
• Total: 9 -- Over: (-110) | Under: (-110)

Twins vs Angels Probable Starting Pitchers

Probable Pitchers: Taj Bradley (Twins) - 6-7, 4.92 ERA vs Jose Urena (Angels) - 0-1, 4.39 ERA

The Twins will give the nod to Taj Bradley (6-7) versus the Angels and Jose Urena (0-1). When Bradley starts, his team is 10-14-0 against the spread this season. Bradley's team has been victorious in 45.5% of the games he's started as the moneyline favorite with a record of 5-6. When Urena starts, the Angels have gone 3-2-0 against the spread. The Angels have been the moneyline underdog in three of Urena's starts this season, and they went 2-1 in those matchups.

Twins vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (52%)

Twins vs Angels Moneyline

• Minnesota is a -118 favorite on the moneyline, while Los Angeles is a -100 underdog at home.

Twins vs Angels Spread

• The Twins are favored by 1.5 runs on the road against the Angels. The Twins are +138 to cover the spread, while the Angels are -166.

Twins vs Angels Over/Under

• Twins versus Angels, on Sept. 10, has an over/under of 9, with the over being -110 and the under -110.

Bet on Minnesota Twins vs. Los Angeles Angels on FanDuel today!

Twins vs Angels Betting Trends

• The Twins have won in 39, or 47%, of the 83 contests they have been named as odds-on favorites in this year.
• This season Minnesota has been victorious 33 times in 64 chances when named as a favorite of at least -118 on the moneyline.
• The Twins' games have gone over the total in 67 of their 140 opportunities.
• The Twins have an against the spread record of 68-72-0 in 140 games with a line this season.
• The Angels are 50-57 in games they were listed as the moneyline underdog (winning 46.7% of those games).
• When playing as a moneyline underdog with odds of -100 or longer, Los Angeles has a record of 41-52 (44.1%).
• The Angels have combined with opponents to hit the over on the total 76 times this season for a 76-62-5 record against the over/under.
• The Angels have put together a 78-65-0 record against the spread this season (covering 54.5% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota with 116 hits and an OBP of .334 this season. He has a .274 batting average and a slugging percentage of .563.
• Among all qualified batters, he is 34th in batting average, his on-base percentage ranks 66th, and he is fourth in slugging.
• Buxton has recorded a base hit in three games in a row. During his last five outings he is hitting .333 with a double, two triples, a home run and two RBIs.
• Trevor Larnach has hit 16 homers this season while driving in 57 runs. He's batting .254 this season and slugging .406 with an on-base percentage of .325.
• He is 85th in batting average, 86th in on-base percentage and 96th in slugging among qualifying hitters.
• Brooks Lee is batting .239 with a .372 slugging percentage and 57 RBI this year.
• Royce Lewis has 12 home runs, 44 RBI and a batting average of .234 this season.

Angels Player Leaders

• Taylor Ward is batting .224 with 30 doubles, two triples, 30 home runs and 72 walks. He's slugging .462 with an on-base percentage of .317.
• Including all the qualifying hitters in the majors, he is 140th in batting average, 100th in on-base percentage and 46th in slugging percentage.
• Jo Adell's 114 hits lead his team. He has a batting average of .243 while slugging .507 with an on-base percentage of .303.
• His batting average is 104th among all qualified players, his on-base percentage ranks 122nd, and he is 17th in slugging.
• Zach Neto has a .472 slugging percentage, which leads the Angels.
• Mike Trout has a .367 on-base percentage to lead his team.

Twins vs Angels Head to Head

• 9/9/2025: 12-2 LAA (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 9/8/2025: 12-3 MIN (Favorite: Angels, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/27/2025: 5-0 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/26/2025: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/25/2025: 11-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 9/11/2024: 6-4 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 9/10/2024: 10-5 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/9/2024: 6-2 LAA (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/28/2024: 11-5 MIN (Favorite: Angels, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/27/2024: 16-5 MIN (Favorite: Angels, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)

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