Angels vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 25

Odds updated as of 7:12 a.m.

The Los Angeles Angels are among the MLB squads in action on Thursday, up against the Kansas City Royals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Angels vs Royals Game Info

• Los Angeles Angels (71-87) vs. Kansas City Royals (79-79)
• Date: Thursday, September 25, 2025
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and FDSKC

Angels vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-108) | KC: (-108)
• Spread: LAA: +1.5 (-178) | KC: -1.5 (+146)
• Total: 9 -- Over: (-122) | Under: (-100)

Angels vs Royals Probable Starting Pitchers

Probable Pitchers: Mitch Farris (Angels) - 1-2, 6.52 ERA vs Michael Lorenzen (Royals) - 6-11, 4.70 ERA

The Angels will give the nod to Mitch Farris (1-2) against the Royals and Michael Lorenzen (6-11). Farris' team is 2-2-0 against the spread in his starts this season. Farris' team lost his only start as a favorite this season. The Royals have a 15-10-0 record against the spread in Lorenzen's starts. The Royals have an 8-7 record in Lorenzen's 15 starts this season when they were the moneyline underdog.

Angels vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (55.7%)

Angels vs Royals Moneyline

• The Angels vs Royals moneyline has Los Angeles as a -108 favorite, while Kansas City is a -108 underdog on the road.

Angels vs Royals Spread

Angels vs Royals Over/Under

• An over/under of 9 has been set for Angels-Royals on Sept. 25, with the over being -122 and the under -100.

Bet on Los Angeles Angels vs. Kansas City Royals on FanDuel today!

Angels vs Royals Betting Trends

• The Angels have won in 18, or 50%, of the 36 contests they have been named as odds-on favorites in this year.
• Los Angeles has a record of 19-20 in contests when oddsmakers favor them by -108 or more on the moneyline.
• The Angels and their opponents have hit the over in 83 of their 156 games with a total set by oddsmakers this season.
• The Angels are 82-74-0 against the spread in their 156 games that had a posted line this season.
• The Royals have won 41 of the 91 games they were listed as the moneyline underdog this season (45.1%).
• When playing as a moneyline underdog with odds of -108 or longer, Kansas City has a 41-50 record (winning 45.1% of its games).
• The Royals have had an over/under set by oddsmakers 156 times, and have combined with opponents to go over the total in 68 of those games (68-86-2).
• The Royals have gone 76-80-0 ATS this season.

Angels Player Leaders

• Taylor Ward leads Los Angeles with a slugging percentage of .477, fueled by 69 extra-base hits. He has a .228 batting average and an on-base percentage of .315.
• Among the qualifying hitters in baseball, his batting average ranks 137th, his on-base percentage ranks 104th, and he is 33rd in slugging.
• Ward will look for his eighth straight game with a hit in this contest. During his last 10 outings he is hitting .282 with six home runs and six RBIs.
• Jo Adell leads Los Angeles with 120 hits. He is batting .235 this season and has 54 extra-base hits. He's also slugging .484 with an on-base percentage of .294.
• He ranks 120th in batting average, 129th in on-base percentage and 25th in slugging among qualifying hitters.
• Nolan Schanuel leads Los Angeles with an OBP of .356 this season while batting .267 with 59 walks and 63 runs scored.
• Mike Trout has 101 hits this season and a team-best OBP of .356.

Royals Player Leaders

• Bobby Witt Jr. has 176 hits with a .498 slugging percentage, both team-best numbers for the Royals. He's batting .291 and with an on-base percentage of .349.
• Including all the qualifying hitters in MLB, he is 12th in batting average, 39th in on-base percentage and 17th in slugging percentage.
• Maikel Garcia paces his team with a .352 on-base percentage. He has a batting average of .286 while slugging .452.
• He is currently 19th in batting average, 34th in on-base percentage and 58th in slugging percentage among all qualifying hitters.
• Vinnie Pasquantino has 31 doubles, a triple, 31 home runs and 48 walks while batting .267.
• Salvador Perez has 34 doubles, 30 home runs and 26 walks while batting .241.

Angels vs Royals Head to Head

• 9/24/2025: 3-2 LAA (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/23/2025: 8-4 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 9/4/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/3/2025: 4-3 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/2/2025: 5-1 LAA (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/21/2024: 3-0 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 8/20/2024: 9-5 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 8/19/2024: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 5/12/2024: 4-2 KC (Favorite: Angels, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/11/2024: 9-3 LAA (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -164, Underdog Moneyline: +138)

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