Yankees vs Rays Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 1:12 a.m.

The Friday schedule in MLB includes a matchup between the New York Yankees and the Tampa Bay Rays.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Rays Game Info

• New York Yankees (30-21) vs. Tampa Bay Rays (33-15)
• Date: Friday, May 22, 2026
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: YES and Rays.TV

Yankees vs Rays Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-162) | TB: (+136)
• Spread: NYY: -1.5 (+130) | TB: +1.5 (-160)
• Total: 8 -- Over: (-110) | Under: (-110)

Yankees vs Rays Probable Starting Pitchers

Probable Pitchers: Gerrit Cole (Yankees) - 0-0, 0.00 ERA vs Nick Martínez (Rays) - 4-1, 1.51 ERA

The probable pitchers are Gerrit Cole for the Yankees and Nick Martinez (4-1) for the Rays. Cole did not pitch as the moneyline favorite last season. The Rays are 7-2-0 against the spread when Martinez starts. The Rays are 5-1 in Martínez's six starts this season that they were the moneyline underdog.

Yankees vs Rays Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (52%)

Yankees vs Rays Moneyline

• New York is the favorite, -162 on the moneyline, while Tampa Bay is a +136 underdog on the road.

Yankees vs Rays Spread

• The Rays are +1.5 on the run line against the Yankees. The Rays are -160 to cover, and the Yankees are +130.

Yankees vs Rays Over/Under

• The over/under for the Yankees versus Rays game on May 22 has been set at 8, with -110 odds on the over and -110 odds on the under.

Bet on New York Yankees vs. Tampa Bay Rays on FanDuel today!

Yankees vs Rays Betting Trends

• The Yankees have been victorious in 27, or 61.4%, of the 44 contests they have been chosen as favorites in this season.
• This season New York has come away with a win 13 times in 20 chances when named as a favorite of at least -162 on the moneyline.
• Contests with the Yankees have gone over the total set by oddsmakers in 21 of 48 chances this season.
• The Yankees have an against the spread mark of 24-24-0 in 48 games with a line this season.
• The Rays have won 60% of the games this season they were the moneyline underdog (12-8).
• Tampa Bay has played as a moneyline underdog of +136 or longer in just one game this season, which it won.
• The Rays have had an over/under set by oddsmakers 47 times, and have combined with opponents to go over the total in 26 of those games (26-21-0).
• The Rays have a 30-17-0 record against the spread this season (covering 63.8% of the time).

Yankees Player Leaders

• Cody Bellinger leads New York in slugging percentage (.469) thanks to 21 extra-base hits. He has a .268 batting average and an on-base percentage of .380.
• Among qualified hitters in MLB, he ranks 56th in batting average, 23rd in on-base percentage, and 44th in slugging.
• Ben Rice leads the Yankees in OBP (.385) and total hits (47) this season. He's batting .288 while slugging .644.
• Among all qualified batters, he is 30th in batting average, 18th in on-base percentage and first in slugging percentage.
• Aaron Judge has 46 hits this season and has a slash line of .250/.381/.554.
• Trent Grisham has been key for New York with 27 hits, an OBP of .305 plus a slugging percentage of .348.
• Grisham has safely hit in two straight games. During his last five outings he is hitting .231 with a double, two walks and an RBI.

Rays Player Leaders

• Junior Caminero has accumulated 49 hits, a team-best for the Rays. He's batting .268 and slugging .508 with an on-base percentage of .357.
• He is 56th in batting average, 48th in on-base percentage and 22nd in slugging percentage among all qualified batters in the big leagues.
• Caminero heads into this game on a five-game hitting streak. In his last five games he is batting .444 with two doubles, two home runs, five walks and eight RBIs.
• Yandy Diaz's .394 OBP and .506 slugging percentage both pace his team. He has a batting average of .316.
• Including all qualified players, he is ninth in batting average, 11th in on-base percentage and 23rd in slugging percentage.
• Jonathan Aranda has seven doubles, eight home runs and 29 walks while batting .263.
• Chandler Simpson is hitting .288 with two doubles, four triples and 10 walks.

Yankees vs Rays Head to Head

• 4/12/2026: 5-4 TB (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 4/11/2026: 5-4 TB (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 4/10/2026: 5-3 TB (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/20/2025: 6-4 NYY (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/19/2025: 13-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/31/2025: 7-4 NYY (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/30/2025: 5-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/29/2025: 7-5 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/28/2025: 4-2 TB (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/4/2025: 7-5 TB (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)

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