Mets vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 1:12 a.m.

The MLB's Friday slate includes the New York Mets facing the Miami Marlins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Mets vs Marlins Game Info

• New York Mets (22-28) vs. Miami Marlins (22-29)
• Date: Friday, May 22, 2026
• Time: 7:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: Marlins.TV and WPIX

Mets vs Marlins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-112) | MIA: (-104)
• Spread: NYM: -1.5 (+146) | MIA: +1.5 (-178)
• Total: 8 -- Over: (-104) | Under: (-118)

Mets vs Marlins Probable Starting Pitchers

Probable Pitchers: Tobias Myers (Mets) - 0-1, 3.41 ERA vs Eury Pérez (Marlins) - 2-6, 5.33 ERA

The probable starters are Tobias Myers (0-1) for the Mets and Eury Perez (2-6) for the Marlins. Myers helped his team cover the spread in his only opportunity this season as a starter. This will be Myers' first game as the moneyline favorite this season. The Marlins have a 4-6-0 record against the spread in Pérez's starts. The Marlins are 1-5 in Pérez's six starts this season that they were the moneyline underdog.

Mets vs Marlins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (50.9%)

Mets vs Marlins Moneyline

• Looking at the moneyline for Mets-Marlins, New York is the favorite at -112, and Miami is -104 playing at home.

Mets vs Marlins Spread

• The Marlins are +1.5 on the run line against the Mets. The Marlins are -178 to cover, and the Mets are +146.

Mets vs Marlins Over/Under

• An over/under of 8 has been set for Mets-Marlins on May 22, with the over being -104 and the under -118.

Bet on New York Mets vs. Miami Marlins on FanDuel today!

Mets vs Marlins Betting Trends

• The Mets have been chosen as favorites in 38 games this year and have walked away with the win 19 times (50%) in those games.
• This season New York has come away with a win 18 times in 37 chances when named as a favorite of at least -112 on the moneyline.
• The Mets and their opponents have gone over the total this season in 21 of their 50 opportunities.
• The Mets have an against the spread mark of 20-30-0 in 50 games with a line this season.
• The Marlins have been the moneyline underdog 23 total times this season. They've finished 4-19 in those games.
• When playing as a moneyline underdog with odds of -104 or longer, Miami has a 4-16 record (winning only 20% of its games).
• The Marlins have combined with opponents to hit the over on the total 31 times this season for a 31-18-1 record against the over/under.
• The Marlins have a 20-30-0 record ATS this season.

Mets Player Leaders

• Juan Soto is hitting .292 with four doubles, a triple, nine home runs and 21 walks. He has an on-base percentage of .388 and a slugging percentage of .546.
• Bo Bichette has an OPS of .604, fueled by an OBP of .276 and a team-best slugging percentage of .328 this season. He's batting .225.
• He ranks 128th in batting average, 152nd in on-base percentage and 148th in slugging in MLB.
• Bichette brings a five-game streak with at least one hit into this matchup. During his last five outings he is hitting .348 with a double, three home runs, a walk and nine RBIs.
• Carson Benge has 43 hits this season and a team-best OBP of .316.
• Benge heads into this matchup with six games in a row with at least one hit. In his last 10 games he is batting .396 with two doubles, a walk and six RBIs.
• Mark Vientos leads New York in total hits (35) this season while batting .233 with 14 extra-base hits.

Marlins Player Leaders

• Xavier Edwards has racked up a team-best .395 on-base percentage. He's batting .316 and slugging .484.
• Including all qualifying hitters, he ranks ninth in batting average, while his on-base percentage is eighth and he is 36th in slugging.
• Edwards enters this game on a seven-game hitting streak. During his last 10 outings he is hitting .293 with a double, a triple, two home runs, three walks and five RBIs.
• Liam Hicks has four doubles, nine home runs and 13 walks while hitting .280. He's slugging .478 with an on-base percentage of .343.
• Including all qualifying hitters, he ranks 38th in batting average, 67th in on-base percentage and 40th in slugging percentage.
• Otto Lopez has racked up 68 hits with a .487 slugging percentage, both team-best statistics for the Marlins.
• Jakob Marsee has five doubles, three triples, three home runs and 28 walks while hitting .209.

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