Mets vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for May 22

Odds updated as of 6:12 p.m.

The Friday slate in MLB includes a matchup between the Miami Marlins and the New York Mets.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Marlins vs Mets Game Info

• Miami Marlins (22-29) vs. New York Mets (22-28)
• Date: Friday, May 22, 2026
• Time: 7:10 p.m. ET
• Venue: loanDepot park -- Miami, Florida
• Coverage: Marlins.TV and WPIX

Marlins vs Mets Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIA: (-112) | NYM: (-104)
• Spread: MIA: +1.5 (-194) | NYM: -1.5 (+160)
• Total: 8 -- Over: (-104) | Under: (-118)

Marlins vs Mets Probable Starting Pitchers

Probable Pitchers: Eury Pérez (Marlins) - 2-6, 5.33 ERA vs Tobias Myers (Mets) - 0-1, 3.41 ERA

The Marlins will give the nod to Eury Perez (2-6, 5.33 ERA), who is eyeing win No. 3 on the season, and the Mets will turn to Tobias Myers (0-1, 3.41 ERA). Pérez's team is 4-6-0 against the spread in his starts this season. Perez's team is 3-1 this season when he starts and they are the moneyline favorite. Myers has started only one game with a set spread, which the Mets covered. The Mets were the underdog on the moneyline for one Myers start this season -- they lost.

Marlins vs Mets Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (54.8%)

Marlins vs Mets Moneyline

• Miami is the favorite, -112 on the moneyline, while New York is a -104 underdog on the road.

Marlins vs Mets Spread

• The Mets are 1.5-run favorites against the spread for this matchup with the Marlins. The Mets are +160 to cover, while the Marlins are -194 to cover as a 1.5-run underdog on the runline.

Marlins vs Mets Over/Under

• The over/under for Marlins-Mets on May 22 is 8. The over is -104, and the under is -118.

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Marlins vs Mets Betting Trends

• The Marlins have been favorites in 26 games this season and have come away with the win 17 times (65.4%) in those contests.
• Miami has a record of 16-7 in contests when bookmakers favor them by -112 or more on the moneyline.
• The Marlins' games have gone over the total in 31 of their 50 opportunities.
• The Marlins have an against the spread mark of 20-30-0 in 50 games with a line this season.
• The Mets have won three of the 11 games they were the underdog on the moneyline this season (27.3%).
• New York has a 3-7 record (winning only 30% of its games) when it has played as a moneyline underdog of -104 or longer.
• The Mets have played in 50 games with a set over/under, and have combined with opponents to go over the total 21 times (21-25-4).
• The Mets have a 20-30-0 record ATS this season.

Marlins Player Leaders

• Xavier Edwards leads Miami in OBP (.395) this season, fueled by 60 hits. He has a .316 batting average and a slugging percentage of .484.
• Among qualifying hitters in MLB, he is ninth in batting average, eighth in on-base percentage, and 35th in slugging.
• Edwards will look for his eighth straight game with a hit in this contest. In his last 10 outings he is hitting .293 with a double, a triple, two home runs, three walks and five RBIs.
• Liam Hicks is hitting .280 with four doubles, nine home runs and 13 walks. He's slugging .478 with an on-base percentage of .343.
• He ranks 37th in batting average, 67th in on-base percentage and 38th in slugging in the major leagues.
• Otto Lopez leads Miami in slugging percentage (.487) and total hits (68) this season.
• Jakob Marsee has three home runs, 14 RBI and a batting average of .203 this season.

Mets Player Leaders

• Juan Soto is hitting .292 with four doubles, a triple, nine home runs and 21 walks. He's slugging .546 with an on-base percentage of .388.
• Bo Bichette paces his team with a .328 slugging percentage. He has a batting average of .225 with an on-base percentage of .276.
• Including all qualifying players, he ranks 128th in batting average, 153rd in on-base percentage and 148th in slugging percentage.
• Carson Benge has a team-high .316 on-base percentage.
• Mark Vientos has collected 35 hits to pace his team.

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