Yankees vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 6:11 p.m.

In MLB action on Tuesday, the New York Yankees face the San Diego Padres.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Padres Game Info

• New York Yankees (19-16) vs. San Diego Padres (23-11)
• Date: Tuesday, May 6, 2025
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: TBS, YES, and SDPA

Yankees vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-124) | SD: (+106)
• Spread: NYY: -1.5 (+164) | SD: +1.5 (-200)
• Total: 7.5 -- Over: (-114) | Under: (-106)

Yankees vs Padres Probable Starting Pitchers

Probable Pitchers: Clarke Schmidt (Yankees) - 0-1, 5.52 ERA vs Michael King (Padres) - 4-1, 2.09 ERA

The probable starters are Clarke Schmidt (0-1) for the Yankees and Michael King (4-1) for the Padres. Schmidt has a record of 0-2-0 ATS in two starts with a spread this season. Schmidt's team is 1-1 this season when he starts and they're favored on the moneyline. The Padres have a 4-3-0 ATS record in King's seven starts with a set spread. The Padres were the underdog on the moneyline for one King start this season -- they won.

Yankees vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (50.4%)

Yankees vs Padres Moneyline

• San Diego is the underdog, +106 on the moneyline, while New York is a -124 favorite at home.

Yankees vs Padres Spread

• The Padres are at the Yankees, and are +1.5 on the runline. The Padres are +164 to cover the spread, and the Yankees are -200.

Yankees vs Padres Over/Under

• An over/under of 7.5 has been set for Yankees-Padres on May 6, with the over being -114 and the under -106.

Bet on New York Yankees vs. San Diego Padres on FanDuel today!

Yankees vs Padres Betting Trends

• The Yankees have won in 17, or 60.7%, of the 28 contests they have been named as odds-on favorites in this year.
• This season New York has come away with a win 16 times in 26 chances when named as a favorite of at least -124 on the moneyline.
• The Yankees and their opponents have gone over the total this season in 15 of their 34 opportunities.
• The Yankees are 16-18-0 against the spread in their 34 games with a line set by sportsbooks this season.
• The Padres have an 8-7 record in games they were the underdog on the moneyline (winning 53.3% of those games).
• San Diego is 5-5 (winning 50% of its games) when playing as a moneyline underdog of +106 or longer.
• The Padres have had an over/under set by bookmakers 33 times, and have combined with opponents to go over the total in 13 of those games (13-19-1).
• The Padres have collected a 20-13-0 record against the spread this season (covering 60.6% of the time).

Yankees Player Leaders

• Aaron Judge leads New York with 55 hits and an OBP of .503, plus a team-best slugging percentage of .759. He's batting .414.
• Among qualified hitters in the majors, he is first in batting average, first in on-base percentage, and first in slugging.
• Paul Goldschmidt is hitting .353 with eight doubles, three home runs and 10 walks, while slugging .481 with an on-base percentage of .400.
• Among all qualifying hitters, he ranks second in batting average, eighth in on-base percentage and 37th in slugging percentage.
• Goldschmidt has picked up a hit in two games in a row. During his last five outings he is hitting .300 with two home runs, a walk and five RBIs.
• Ben Rice has 27 hits this season and has a slash line of .255/.358/.557.
• Trent Grisham is batting .298 with a .379 OBP and 17 RBI for New York this season.
• Grisham has hit safely in three straight games. During his last five outings he is hitting .313 with a home run, three walks and two RBIs.

Padres Player Leaders

• Fernando Tatis Jr. has 40 hits with a .387 on-base percentage and a .556 slugging percentage, all club-highs for the Padres. He's batting .317.
• Including all qualifying hitters in the big leagues, his batting average places him eighth, his on-base percentage ranks 20th, and he is 13th in slugging.
• Manny Machado is batting .294 with 12 doubles, three home runs and 13 walks. He's slugging .460 with an on-base percentage of .357.
• He is currently 25th in batting average, 47th in on-base percentage and 50th in slugging percentage among all qualified hitters.
• Luis Arraez has four doubles, a triple, three home runs and six walks while batting .297.
• Xander Bogaerts is hitting .254 with nine doubles, a home run and 16 walks.

Yankees vs Padres Head to Head

• 5/5/2025: 4-3 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2024: 5-2 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/25/2024: 4-1 NYY (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/24/2024: 8-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/28/2023: 10-7 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/27/2023: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/26/2023: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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