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Padres vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 2

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Padres vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 2

Odds updated as of 8:11 a.m.

The Saturday schedule in MLB includes a matchup between the San Diego Padres and the St. Louis Cardinals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Padres vs Cardinals Game Info

  • San Diego Padres (61-49) vs. St. Louis Cardinals (55-56)
  • Date: Saturday, August 2, 2025
  • Time: 10:10 p.m. ET
  • Venue: PETCO Park -- San Diego, California
  • Coverage: SDPA and FDSMW

Padres vs Cardinals Odds & Moneyline

  • All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
  • Moneyline: SD: (-138) | STL: (+118)
  • Spread: SD: -1.5 (+146) | STL: +1.5 (-178)
  • Total: 8.5 -- Over: (-115) | Under: (-105)

Padres vs Cardinals Probable Starting Pitchers

Probable Pitchers: Randy Vasquez (Padres) - 3-4, 3.65 ERA vs Michael McGreevy (Cardinals) - 2-2, 4.91 ERA

This contest's pitching matchup is set, as the Padres will send Randy Vasquez (3-4) to the mound, while Michael McGreevy (2-2) will answer the bell for the Cardinals. When Vasquez starts, his team is 13-7-0 against the spread this season. Vasquez and his team have won each of the five games he's started as the moneyline favorite. The Cardinals are 3-2-0 against the spread when McGreevy starts. The Cardinals were the underdog on the moneyline for two McGreevy starts this season -- they split the games.

Padres vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.2%)

Padres vs Cardinals Moneyline

  • The moneyline numbers for Padres vs. Cardinals reveal San Diego as the favorite (-138) and St. Louis as the underdog (+118) on the road.

Padres vs Cardinals Spread

  • The Padres are hosting the Cardinals and are favored by 1.5 runs (+146 to cover) on the runline. St. Louis is -178 to cover.

Padres vs Cardinals Over/Under

  • The Padres-Cardinals game on Aug. 2 has been given an over/under of 8.5 runs. The over is set at -115 and the under at -105.

Bet on San Diego Padres vs. St. Louis Cardinals on FanDuel today!

Padres vs Cardinals Betting Trends

  • The Padres have come away with 33 wins in the 54 contests they have been listed as the favorites in this season.
  • This season San Diego has been victorious 22 times in 35 chances when named as a favorite of at least -138 on the moneyline.
  • The Padres' games have gone over the total in 44 of their 108 opportunities.
  • In 108 games with a line this season, the Padres have a mark of 60-48-0 against the spread.
  • The Cardinals are 27-28 in games they were listed as the moneyline underdog (winning 49.1% of those games).
  • In games it has played as a moneyline underdog with odds of +118 or longer, St. Louis has an 8-15 record (winning just 34.8% of its games).
  • The Cardinals have played in 108 games with an over/under set, and have combined with their opponents to go over the total 54 times (54-49-5).
  • The Cardinals have put together a 56-52-0 record against the spread this season.

Padres Player Leaders

  • Manny Machado has 128 hits to go with a slugging percentage of .507, both of which are best among San Diego hitters this season. He has a .302 batting average and an on-base percentage of .361.
  • Among qualifying hitters in the majors, his batting average ranks seventh, his on-base percentage ranks 29th, and he is 18th in slugging.
  • Machado will look for his 10th straight game with a hit in this matchup. In his last 10 games he is hitting .452 with four doubles, two home runs and 11 RBIs.
  • Fernando Tatis Jr. has 18 doubles, two triples, 17 home runs and 61 walks. He's batting .267 and slugging .446 with an on-base percentage of .368.
  • He ranks 61st in batting average, 21st in on-base percentage and 68th in slugging among qualified hitters.
  • Luis Arraez has collected 125 base hits, an OBP of .333 and a slugging percentage of .406 this season.
  • Arraez has recorded at least one base hit in 14 games in a row. During his last 10 games he is hitting .425 with three doubles, a home run, three walks and five RBIs.
  • Xander Bogaerts has seven home runs, 37 RBI and a batting average of .267 this season.
  • Bogaerts enters this game on a two-game hitting streak. In his last five games he is hitting .273 with a double, a home run, a walk and two RBIs.

Cardinals Player Leaders

  • Brendan Donovan has put up an on-base percentage of .354 and a slugging percentage of .412. Both lead the Cardinals. He's batting .282.
  • Including all qualifying hitters, he is 27th in batting average, while his on-base percentage is 39th and he is 93rd in slugging.
  • Alec Burleson paces his team with 96 hits. He has a batting average of .284 while slugging .464 with an on-base percentage of .338.
  • Including all qualified hitters, his batting average puts him 24th, his on-base percentage ranks 62nd, and he is 46th in slugging.
  • Willson Contreras is hitting .257 with 28 doubles, 15 home runs and 34 walks.
  • Masyn Winn is batting .271 with 23 doubles, seven home runs and 27 walks.

Padres vs Cardinals Head to Head

  • 8/1/2025: 4-1 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
  • 7/27/2025: 9-2 SD (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
  • 7/26/2025: 3-1 SD (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
  • 7/25/2025: 3-0 STL (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
  • 7/24/2025: 9-7 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
  • 8/29/2024: 4-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
  • 8/28/2024: 4-3 STL (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
  • 8/27/2024: 7-5 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
  • 8/26/2024: 7-4 SD (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
  • 4/3/2024: 3-2 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)

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