Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 17

Odds updated as of 1:16 a.m.

The New York Yankees will face the St. Louis Cardinals in MLB action on Sunday.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Yankees vs Cardinals Game Info

• New York Yankees (66-57) vs. St. Louis Cardinals (61-63)
• Date: Sunday, August 17, 2025
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and YES

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-146) | STL: (+124)
• Spread: NYY: -1.5 (+115) | STL: +1.5 (-138)
• Total: 9.5 -- Over: (-100) | Under: (-122)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 7-5, 4.34 ERA vs Miles Mikolas (Cardinals) - 6-9, 4.97 ERA

The probable starters are Will Warren (7-5) for the Yankees and Miles Mikolas (6-9) for the Cardinals. Warren's team is 10-15-0 against the spread this season in his starts. Warren's team has a record of 13-8 this season when he starts and they are the favorite on the moneyline. The Cardinals have gone 10-13-0 against the spread when Mikolas starts. The Cardinals have been the underdog on the moneyline in 16 of Mikolas' starts this season, and they went 7-9 in those games.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (54.6%)

Yankees vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Yankees, St. Louis is the underdog at +124, and New York is -146 playing on the road.

Yankees vs Cardinals Spread

• The Yankees are 1.5-run road favorites on the runline against the Cardinals. The Yankees are +115 to cover, and the Cardinals are -138.

Yankees vs Cardinals Over/Under

• Yankees versus Cardinals on Aug. 17 has an over/under of 9.5 runs, with the odds on the over -100 and the under set at -122.

Bet on New York Yankees vs. St. Louis Cardinals on FanDuel today!

Yankees vs Cardinals Betting Trends

• The Yankees have come away with 58 wins in the 102 contests they have been listed as the favorites in this season.
• This season New York has been victorious 43 times in 66 chances when named as a favorite of at least -146 on the moneyline.
• The Yankees' games have gone over the total in 55 of their 121 opportunities.
• In 121 games with a line this season, the Yankees have a mark of 52-69-0 against the spread.
• The Cardinals have a 31-33 record in games they were listed as the moneyline underdog (winning 48.4% of those games).
• St. Louis has a record of 10-14 when it has played as a moneyline underdog with odds of +124 or longer (41.7%).
• The Cardinals have had an over/under set by oddsmakers 119 times, and have combined with opponents to go over the total in 60 of those games (60-54-5).
• The Cardinals have covered 51.3% of their games this season, going 61-58-0 against the spread.

Yankees Player Leaders

• Aaron Judge leads New York in OBP (.445), slugging percentage (.689) and total hits (136) this season. He has a .333 batting average.
• Among qualifying hitters in MLB, he is first in batting average, first in on-base percentage, and first in slugging.
• Cody Bellinger has 20 doubles, five triples, 22 home runs and 37 walks. He's batting .267 and slugging .485 with an on-base percentage of .322.
• Among qualified batters, his batting average ranks him 53rd, his on-base percentage 95th, and his slugging percentage 29th.
• Anthony Volpe is batting .215 with a .413 slugging percentage and 65 RBI this year.
• Trent Grisham has been key for New York with 90 hits, an OBP of .354 plus a slugging percentage of .456.

Cardinals Player Leaders

• Brendan Donovan has a .348 on-base percentage and a .402 slugging percentage, both team-high numbers for the Cardinals. He's batting .279.
• Including all qualifying hitters, he ranks 30th in batting average, while his on-base percentage ranks 46th and he is 103rd in slugging.
• Alec Burleson paces his team with 110 hits. He has a batting average of .284 while slugging .454 with an on-base percentage of .336.
• Including all qualified hitters, his batting average puts him 24th, his on-base percentage is 64th, and he is 57th in slugging.
• Masyn Winn has 26 doubles, nine home runs and 31 walks while batting .267.
• Willson Contreras has 29 doubles, 16 home runs and 39 walks while hitting .255.

Yankees vs Cardinals Head to Head

• 8/16/2025: 12-8 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/15/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/1/2024: 14-7 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/31/2024: 6-5 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/30/2024: 6-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2023: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/1/2023: 6-2 NYY (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/1/2023: 11-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/7/2022: 12-9 STL (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/6/2022: 1-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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