Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 17

Odds updated as of 2:13 p.m.

The Sunday schedule in MLB includes a matchup between the New York Yankees and the St. Louis Cardinals.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Cardinals Game Info

• New York Yankees (66-57) vs. St. Louis Cardinals (61-63)
• Date: Sunday, August 17, 2025
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and YES

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-158) | STL: (+134)
• Spread: NYY: -1.5 (+104) | STL: +1.5 (-125)
• Total: 9 -- Over: (-100) | Under: (-122)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 7-5, 4.34 ERA vs Miles Mikolas (Cardinals) - 6-9, 4.97 ERA

The probable starters are Will Warren (7-5) for the Yankees and Miles Mikolas (6-9) for the Cardinals. Warren's team is 10-15-0 against the spread this season in his starts. Warren's team has won 61.9% of his starts when they are favored on the moneyline (13-8). When Mikolas starts, the Cardinals have gone 10-13-0 against the spread. The Cardinals have been the underdog on the moneyline in 16 of Mikolas' starts this season, and they went 7-9 in those matchups.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (54.8%)

Yankees vs Cardinals Moneyline

• The Yankees vs Cardinals moneyline has New York as a -158 favorite, while St. Louis is a +134 underdog at home.

Yankees vs Cardinals Spread

• The Cardinals are hosting the Yankees, and are +1.5 on the runline. The Cardinals are +104 to cover the spread, and the Yankees are -125.

Yankees vs Cardinals Over/Under

• The Yankees-Cardinals game on Aug. 17 has been given an over/under of 9 runs. The over is set at -100 and the under at -122.

Bet on New York Yankees vs. St. Louis Cardinals on FanDuel today!

Yankees vs Cardinals Betting Trends

• The Yankees have won in 58, or 56.9%, of the 102 contests they have been named as odds-on favorites in this year.
• New York has not played a game this season with better moneyline odds than -158.
• Contests with the Yankees have gone over the total set by bookmakers in 55 of 121 chances this season.
• In 121 games with a line this season, the Yankees have a mark of 52-69-0 against the spread.
• The Cardinals have put together a 31-33 record in games they were the underdog on the moneyline (winning 48.4% of those games).
• St. Louis has not yet played a game with moneyline odds of +134 or longer.
• The Cardinals have played in 119 games with an over/under set, and have combined with opponents to go over the total 60 times (60-54-5).
• The Cardinals have a 61-58-0 record ATS this season (covering 51.3% of the time).

Yankees Player Leaders

• Aaron Judge leads New York with 136 hits and an OBP of .445, plus a team-best slugging percentage of .689. He's batting .333.
• He ranks first in batting average, first in on-base percentage, and first in slugging among qualified hitters in baseball.
• Cody Bellinger is hitting .267 with 20 doubles, five triples, 22 home runs and 37 walks. He's slugging .485 with an on-base percentage of .322.
• Among qualified hitters, he is 53rd in batting average, 95th in on-base percentage and 29th in slugging percentage.
• Anthony Volpe has collected 94 base hits, an OBP of .283 and a slugging percentage of .413 this season.
• Trent Grisham has 21 home runs, 46 RBI and a batting average of .250 this season.

Cardinals Player Leaders

• Brendan Donovan has racked up an on-base percentage of .348 and a slugging percentage of .402. Both lead the Cardinals. He's batting .279.
• He is 30th in batting average, 46th in on-base percentage and 103rd in slugging percentage among all qualified batters in the big leagues.
• Alec Burleson has 110 hits to lead his team. He has a batting average of .284 while slugging .454 with an on-base percentage of .336.
• Including all qualified hitters, he ranks 24th in batting average, 64th in on-base percentage and 57th in slugging percentage.
• Willson Contreras is batting .255 with 29 doubles, 16 home runs and 39 walks.
• Masyn Winn is batting .267 with 26 doubles, nine home runs and 31 walks.

Yankees vs Cardinals Head to Head

• 8/16/2025: 12-8 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/15/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/1/2024: 14-7 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/31/2024: 6-5 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/30/2024: 6-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2023: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/1/2023: 6-2 NYY (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/1/2023: 11-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 8/7/2022: 12-9 STL (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/6/2022: 1-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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