Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 15

Odds updated as of 5:19 a.m.

Friday's slate in the MLB includes a matchup between the New York Yankees and the St. Louis Cardinals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Yankees vs Cardinals Game Info

• New York Yankees (64-57) vs. St. Louis Cardinals (61-61)
• Date: Friday, August 15, 2025
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and YES

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-134) | STL: (+114)
• Spread: NYY: -1.5 (+120) | STL: +1.5 (-144)
• Total: 9 -- Over: (-102) | Under: (-120)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Luis Gil (Yankees) - 0-1, 7.27 ERA vs Andre Pallante (Cardinals) - 6-9, 4.95 ERA

The Yankees will look to Luis Gil (0-1) against the Cardinals and Andre Pallante (6-9). Gil has a record of 1-1-0 ATS in two starts with a spread this season. Gil's team is 1-1 this season when he starts and they're favored on the moneyline. When Pallante starts, the Cardinals have gone 12-11-0 against the spread. The Cardinals have a 6-8 record in Pallante's 14 starts this season when they were the moneyline underdog.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (50.6%)

Yankees vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Yankees, St. Louis is the underdog at +114, and New York is -134 playing on the road.

Yankees vs Cardinals Spread

• The Yankees are 1.5-run road favorites on the runline against the Cardinals. The Yankees are +120 to cover, and the Cardinals are -144.

Yankees vs Cardinals Over/Under

• Yankees versus Cardinals on Aug. 15 has an over/under of 9 runs, with the odds on the over -102 and the under set at -120.

Bet on New York Yankees vs. St. Louis Cardinals on FanDuel today!

Yankees vs Cardinals Betting Trends

• The Yankees have won in 56, or 56%, of the 100 contests they have been named as odds-on favorites in this year.
• New York has a record of 45-32 in contests when bookmakers favor them by -134 or more on the moneyline.
• The Yankees and their opponents have gone over the total this season in 54 of their 119 opportunities.
• The Yankees have posted a record of 51-68-0 against the spread this season.
• The Cardinals are 31-31 in games they were the underdog on the moneyline (winning 50% of those games).
• St. Louis has a record of 14-19 in games it has played as a moneyline underdog with odds of +114 or longer (42.4%).
• The Cardinals have combined with opponents to go over the total 59 times this season for a 59-53-5 record against the over/under.
• The Cardinals have a 60-57-0 record against the spread this season (covering 51.3% of the time).

Yankees Player Leaders

• Aaron Judge leads New York with 134 hits and an OBP of .444, plus a team-best slugging percentage of .687. He's batting .333.
• Among all qualified hitters in baseball, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Cody Bellinger has 20 doubles, five triples, 22 home runs and 37 walks. He's batting .270 and slugging .491 with an on-base percentage of .325.
• Among qualifying hitters, he ranks 49th in batting average, 84th in on-base percentage and 27th in slugging percentage.
• Anthony Volpe has collected 94 base hits, an OBP of .288 and a slugging percentage of .422 this season.
• Volpe brings a three-game hitting streak into this game. During his last five outings he is batting .176 with a double, a home run, three walks and three RBIs.
• Trent Grisham has been key for New York with 86 hits, an OBP of .346 plus a slugging percentage of .455.
• Grisham has safely hit in three straight games. In his last five games he is hitting .300 with a home run, a walk and two RBIs.

Cardinals Player Leaders

• Brendan Donovan has accumulated a .348 on-base percentage and a .402 slugging percentage, both team-best marks for the Cardinals. He's batting .279.
• Including all qualified players, he is 31st in batting average, while his on-base percentage ranks 45th and he is 105th in slugging.
• Alec Burleson has 107 hits to pace his team. He has a batting average of .282 while slugging .450 with an on-base percentage of .334.
• Including all qualified hitters, his batting average puts him 28th, his on-base percentage ranks 67th, and he is 63rd in slugging.
• Willson Contreras is batting .255 with 29 doubles, 16 home runs and 39 walks.
• Masyn Winn is hitting .264 with 25 doubles, eight home runs and 30 walks.

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