Virginia Tech vs Vanderbilt Prediction, Odds, Picks, Best Bets for Week 2 2025

The Virginia Tech Hokies versus the Vanderbilt Commodores is on the college football schedule for Saturday.
Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding today's NCAA football betting odds.
Virginia Tech vs Vanderbilt Odds & Spread
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- All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: Virginia Tech: (-114) | Vanderbilt: (-105)
- Spread: Virginia Tech: -1.5 (-105) | Vanderbilt: +1.5 (-115)
- Total: 47.5 -- Over: (-105) | Under: (-115)
Virginia Tech vs Vanderbilt Betting Trends
- Virginia Tech hasn't won a game against the spread this season.
- Vanderbilt has covered the spread in every game this year.
- No Vanderbilt game has gone over the point total this year.
Virginia Tech vs Vanderbilt Prediction & Pick
All college football win probability predictions and picks are according to numberFire.
Prediction: Hokies win (58.6%)
Virginia Tech vs Vanderbilt Point Spread
Vanderbilt is listed as an underdog by 1.5 points (-115 odds), and Virginia Tech, the favorite, is -105 to cover.
Virginia Tech vs Vanderbilt Over/Under
The over/under for Virginia Tech-Vanderbilt on Sept. 6 is 47.5. The over is -105, and the under is -115.
Virginia Tech vs Vanderbilt Moneyline
Looking at the moneyline for Virginia Tech-Vanderbilt, Virginia Tech is the favorite at -114, and Vanderbilt is -105.
Virginia Tech vs. Vanderbilt Points Insights
- The average implied total for the Hokies last season was 30.1 points, 5.1 more points than their implied total of 25 points in Saturday's game.
- The 32.1-point average implied total last season for the Commodores is 9.1 more points than the team's 23-point implied total in this matchup.
Virginia Tech vs. Vanderbilt Game Info
- Game day: Saturday, September 6, 2025
- Game time: 7:30 p.m. ET
- TV channel: ACC Network
- Location: Blacksburg, Virginia
- Stadium: Lane Stadium
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