Yankees vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 7:13 p.m.

On Thursday in MLB, the New York Yankees are playing the Houston Astros.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Yankees vs Astros Game Info

• New York Yankees (77-62) vs. Houston Astros (77-63)
• Date: Thursday, September 4, 2025
• Time: 7:40 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: MLB Network, SCHN, and YES

Yankees vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-142) | HOU: (+120)
• Spread: NYY: -1.5 (+114) | HOU: +1.5 (-137)
• Total: 9 -- Over: (-118) | Under: (-104)

Yankees vs Astros Probable Starting Pitchers

Probable Pitchers: Carlos Rodon (Yankees) - 15-7, 3.18 ERA vs Cristian Javier (Astros) - 1-1, 3.38 ERA

This contest's pitching matchup is set, as the Yankees will send Carlos Rodon (15-7) to the mound, while Cristian Javier (1-1) will take the ball for the Astros. Rodon and his team are 11-17-0 ATS this season when he starts. Rodon's team has a record of 15-12 this season when he starts and they are the favorite on the moneyline. The Astros have a 2-2-0 record against the spread in Javier's starts. The Astros were the moneyline underdog for two Javier starts this season -- they won both.

Yankees vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (53.7%)

Yankees vs Astros Moneyline

• Houston is a +120 underdog on the moneyline, while New York is a -142 favorite on the road.

Yankees vs Astros Spread

• The Yankees are at the Astros and are favored by 1.5 runs on the spread. The Yankees are +114 to cover the runline, with the Astros being -137.

Yankees vs Astros Over/Under

• A combined run total of 9 has been set for Yankees-Astros on Sept. 4, with the over at -118 and the under at -104.

Bet on New York Yankees vs. Houston Astros on FanDuel today!

Yankees vs Astros Betting Trends

• The Yankees have been chosen as favorites in 116 games this year and have walked away with the win 68 times (58.6%) in those games.
• New York has a record of 53-32 when favored by -142 or more this year.
• The Yankees and their opponents have hit the over in 67 of their 137 games with a total set by oddsmakers this season.
• The Yankees have an against the spread record of 63-74-0 in 137 games with a line this season.
• The Astros have gone 27-19 in games they were the underdog on the moneyline (winning 58.7% of those games).
• When it has played as a moneyline underdog with odds of +120 or longer, Houston has a 9-3 record (winning 75% of its games).
• The Astros have had an over/under set by bookmakers 139 times, and have combined with opponents to go over the total in 63 of those games (63-72-4).
• The Astros have covered 49.6% of their games this season, going 69-70-0 ATS.

Yankees Player Leaders

• Aaron Judge has 152 hits and an OBP of .440 to go with a slugging percentage of .666. All three of those stats are tops among New York hitters this season. He has a .323 batting average, as well.
• Among all qualifying hitters in MLB, his batting average ranks first, his on-base percentage ranks first, and he is first in slugging.
• Judge hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .333 with a double, two home runs, four walks and two RBIs.
• Cody Bellinger has 23 doubles, five triples, 27 home runs and 43 walks. He's batting .278 and slugging .505 with an on-base percentage of .332.
• Among qualifying batters, he ranks 29th in batting average, 72nd in on-base percentage and 17th in slugging percentage.
• Bellinger has picked up at least one hit in four straight games. During his last five outings he is hitting .182 with a double, a home run, two walks and five RBIs.
• Trent Grisham has collected 103 base hits, an OBP of .355 and a slugging percentage of .480 this season.
• Jazz Chisholm has been key for New York with 93 hits, an OBP of .341 plus a slugging percentage of .501.
• Chisholm brings a two-game hitting streak into this game. In his last five games he is batting .263 with a double, two home runs, four walks and four RBIs.

Astros Player Leaders

• Jose Altuve has accumulated a team-high .452 slugging percentage. He's batting .270 with an on-base percentage of .332.
• He ranks 45th in batting average, 72nd in on-base percentage and 59th in slugging percentage among all qualified batters in MLB.
• Jeremy Pena's 132 hits and .368 on-base percentage are both team-highs. He has a batting average of .306 while slugging .480.
• Including all qualifying players, he ranks fifth in batting average, 15th in on-base percentage and 35th in slugging percentage.
• Yainer Diaz has 19 doubles, a triple, 18 home runs and 19 walks while batting .253.
• Christian Walker is hitting .235 with 21 doubles, a triple, 21 home runs and 39 walks.

Yankees vs Astros Head to Head

• 9/3/2025: 8-7 HOU (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/2/2025: 7-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/10/2025: 7-1 HOU (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)
• 8/9/2025: 5-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/8/2025: 5-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/9/2024: 4-3 HOU (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/8/2024: 9-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/7/2024: 10-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 3/31/2024: 4-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 3/30/2024: 5-3 NYY (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)

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