Twins vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 21

Odds updated as of 10:13 p.m.

The Minnesota Twins are among the MLB teams in action on Thursday, up against the Athletics.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Twins vs Athletics Game Info

• Minnesota Twins (58-67) vs. Athletics (57-70)
• Date: Thursday, August 21, 2025
• Time: 1:10 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and NBCS-CA

Twins vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-116) | OAK: (-102)
• Spread: MIN: +1.5 (-182) | OAK: -1.5 (+150)
• Total: 9.5 -- Over: (-105) | Under: (-115)

Twins vs Athletics Probable Starting Pitchers

Probable Pitchers: TBA (Twins) vs Jack Perkins (Athletics) - 2-2, 0.00 ERA

Perkins (2-2) gets the start for the Athletics. As of this writing, there's been no pitching decision announced by the Twins. The Athletics are 2-1-0 against the spread when Perkins starts. The Athletics were the underdog on the moneyline for one Perkins start this season -- they won.

Twins vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (53%)

Twins vs Athletics Moneyline

• The Twins vs Athletics moneyline has the Twins as a -116 favorite, while the Athletics are a -102 underdog on the road.

Twins vs Athletics Spread

• The Twins are hosting the Athletics and are 1.5 on the runline and -182 to cover, while Sacramento is +150 to cover the spread.

Twins vs Athletics Over/Under

• A combined run total of 9.5 has been set for Twins-Athletics on Aug. 21, with the over at -105 and the under at -115.

Bet on Minnesota Twins vs. Athletics on FanDuel today!

Twins vs Athletics Betting Trends

• The Twins have been favorites in 72 games this season and have come away with the win 37 times (51.4%) in those contests.
• This year, the Twins have won 32 of 60 games when listed as at least -116 or better on the moneyline.
• The Twins and their opponents have hit the over in 52 of their 120 games with a total this season.
• The Twins have an against the spread mark of 60-60-0 in 120 games with a line this season.
• The Athletics have won 42.6% of the games this season they were the moneyline underdog (40-54).
• When playing as a moneyline underdog with odds of -102 or longer, the Athletics have gone 35-53 (39.8%).
• The Athletics have played in 126 games with an over/under set, and have combined with their opponents to go over the total 63 times (63-57-6).
• The Athletics have collected a 65-61-0 record ATS this season (covering 51.6% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota with 99 hits and a team-best slugging percentage of .550. He's batting .277 with an on-base percentage of .337.
• Among qualified hitters in baseball, he ranks 34th in batting average, 61st in on-base percentage, and sixth in slugging.
• Trevor Larnach is batting .245 with 17 doubles, a triple, 16 home runs and 41 walks. He's slugging .414 with an on-base percentage of .319.
• His batting average ranks 110th among qualified players, his on-base percentage 101st, and his slugging percentage 92nd.
• Larnach brings a two-game streak with at least one hit into this contest. In his last five games he is hitting .222 with two doubles and three walks.
• Ryan Jeffers leads Minnesota in OBP (.351) this season, fueled by 91 hits.
• Jeffers has logged a hit or more in three straight games. In his last five games he is batting .222 with a home run, three walks and two RBIs.
• Brooks Lee has been key for Minnesota with 90 hits, an OBP of .288 plus a slugging percentage of .390.
• Lee takes a six-game hitting streak into this game. During his last 10 games he is batting .243 with two doubles, a triple, two home runs, two walks and eight RBIs.

Athletics Player Leaders

• Brent Rooker has a .497 slugging percentage, which paces the Athletics. He's batting .273 with an on-base percentage of .346.
• Including all the qualifying hitters in MLB, his batting average places him 43rd, his on-base percentage ranks 47th, and he is 23rd in slugging.
• Tyler Soderstrom is batting .264 with 23 doubles, a triple, 22 home runs and 45 walks. He's slugging .466 with an on-base percentage of .336.
• His batting average is 60th among all qualified players, his on-base percentage ranks 64th, and he is 47th in slugging.
• Shea Langeliers leads the Athletics with 97 hits.
• Nick Kurtz is batting .313 with 23 doubles, two triples, 25 home runs and 45 walks.

Twins vs Athletics Head to Head

• 8/19/2025: 6-3 OAK (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 6/5/2025: 14-3 OAK (Favorite: Twins, Spread: -1.5, Total: 10, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 6/4/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 10, Favorite Moneyline: -176, Underdog Moneyline: +148)
• 6/3/2025: 10-3 MIN (Favorite: Twins, Spread: -1.5, Total: 10, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/2/2025: 10-4 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/23/2024: 3-0 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/22/2024: 10-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/21/2024: 6-5 OAK (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/16/2024: 8-7 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/16/2024: 6-2 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)

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