Tigers vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 6:12 p.m.

The MLB's Wednesday schedule includes the Detroit Tigers facing the Boston Red Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Tigers vs Red Sox Game Info

• Detroit Tigers (18-19) vs. Boston Red Sox (15-21)
• Date: Wednesday, May 6, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: DSN and NESN

Tigers vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-108) | BOS: (-108)
• Spread: DET: +1.5 (-184) | BOS: -1.5 (+152)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Tigers vs Red Sox Probable Starting Pitchers

Probable Pitchers: Jack Flaherty (Tigers) - 0-2, 5.90 ERA vs Sonny Gray (Red Sox) - 2-1, 4.30 ERA

The Tigers will call on Jack Flaherty (0-2) against the Red Sox and Sonny Gray (2-1). Flaherty's team is 2-5-0 against the spread this season in his starts. Flaherty's team is 2-3 this season when he starts and they are the moneyline favorite. The Red Sox have a 3-2-0 record against the spread in Gray's starts. The Red Sox have always been the moneyline underdog when Gray starts this season.

Tigers vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (58.6%)

Tigers vs Red Sox Moneyline

• Detroit is the favorite, -108 on the moneyline, while Boston is a -108 underdog on the road.

Tigers vs Red Sox Spread

Tigers vs Red Sox Over/Under

• An over/under of 8.5 has been set for Tigers-Red Sox on May 6, with the over being -108 and the under -112.

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Tigers vs Red Sox Betting Trends

• The Tigers have come away with 13 wins in the 24 contests they have been listed as the favorites in this season.
• This season Detroit has come away with a win 13 times in 26 chances when named as a favorite of at least -108 on the moneyline.
• Contests with the Tigers have gone over the total set by bookmakers in 18 of 37 chances this season.
• The Tigers have an against the spread record of 19-18-0 in 37 games with a line this season.
• The Red Sox have compiled a 4-8 record in games they were listed as the moneyline underdog (winning 33.3% of those games).
• Boston is 4-8 (winning just 33.3% of its games) when playing as a moneyline underdog of -108 or longer.
• The Red Sox have played in 36 games with an over/under set, and have combined with their opponents to go over the total 18 times (18-17-1).
• The Red Sox have put together a 12-24-0 record ATS this season (covering just 33.3% of the time).

Tigers Player Leaders

• Kevin McGonigle leads Detroit OPS (.869) this season. He has a .308 batting average, an on-base percentage of .403, and a slugging percentage of .466.
• Among qualified hitters in baseball, his batting average ranks 19th, his on-base percentage ranks 10th, and he is 46th in slugging.
• Riley Greene is batting .290 with nine doubles, four home runs and 22 walks. He's slugging .450 with an on-base percentage of .392.
• Among qualified hitters, his batting average ranks him 33rd, his on-base percentage 17th, and his slugging percentage 51st.
• Greene has picked up at least one hit in two games in a row. During his last five outings he is hitting .333 with a double, two walks and an RBI.
• Dillon Dingler leads Detroit in total hits (28) this season, and 13 of those have gone for extra bases.
• Dingler takes a five-game hitting streak into this game. In his last five games he is hitting .333 with two doubles, a home run and seven RBIs.
• Spencer Torkelson is batting .212 with a .336 OBP and 14 RBI for Detroit this season.

Red Sox Player Leaders

• Wilyer Abreu has racked up a team-high OBP (.393) and slugging percentage (.485). He's batting .311.
• Including all the qualified hitters in MLB, his batting average ranks 18th, his on-base percentage ranks 16th, and he is 38th in slugging.
• Willson Contreras has collected 34 hits to lead his team. He has a batting average of .270 while slugging .492 with an on-base percentage of .382.
• He is 51st in batting average, 26th in on-base percentage and 34th in slugging percentage in MLB.
• Jarren Duran has five doubles, four home runs and eight walks while hitting .195.
• Ceddanne Rafaela is batting .276 with four doubles, two triples, two home runs and six walks.

Tigers vs Red Sox Head to Head

• 5/5/2026: 10-3 BOS (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/4/2026: 5-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/20/2026: 8-6 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/19/2026: 6-2 DET (Favorite: Red Sox, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/18/2026: 4-1 DET (Favorite: Tigers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/17/2026: 1-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/28/2025: 4-3 BOS (Favorite: Tigers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/27/2025: 2-1 DET (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/26/2025: 4-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/14/2025: 6-5 DET (Favorite: Tigers, Spread: -1.5, Total: 7, Favorite Moneyline: -245, Underdog Moneyline: +200)

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