Phillies vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 1:11 a.m.

Wednesday's slate in the MLB includes a matchup between the Philadelphia Phillies and the Athletics.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Phillies vs Athletics Game Info

• Philadelphia Phillies (16-20) vs. Athletics (18-17)
• Date: Wednesday, May 6, 2026
• Time: 6:40 p.m. ET
• Venue: Citizens Bank Park -- Philadelphia, Pennsylvania
• Coverage: NBCS-PH and NBCS-CA

Phillies vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PHI: (-166) | OAK: (+140)
• Spread: PHI: -1.5 (+122) | OAK: +1.5 (-146)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Phillies vs Athletics Probable Starting Pitchers

Probable Pitchers: Zack Wheeler (Phillies) - 1-0, 2.45 ERA vs Jeffrey Springs (Athletics) - 3-2, 3.96 ERA

This contest's pitching matchup is set, as the Phillies will send Zack Wheeler (1-0) to the mound, while Jeffrey Springs (3-2) will answer the bell for the Athletics. Wheeler has a record of 1-1-0 ATS in two starts with a spread this season. Wheeler's team won his only start as a favorite this season. When Springs starts, the Athletics are 6-1-0 against the spread. The Athletics have been the moneyline underdog in four of Springs' starts this season, and they went 2-2 in those matchups.

Phillies vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Phillies win (60.4%)

Phillies vs Athletics Moneyline

• The Phillies vs Athletics moneyline has the Phillies as a -166 favorite, while the Athletics are a +140 underdog on the road.

Phillies vs Athletics Spread

• The Phillies are 1.5-run favorites on the runline against the Athletics. The Phillies are +122 to cover, while the Athletics are -146 to cover.

Phillies vs Athletics Over/Under

• An over/under of 8.5 has been set for Phillies-Athletics on May 6, with the over being -110 and the under -110.

Bet on Philadelphia Phillies vs. Athletics on FanDuel today!

Phillies vs Athletics Betting Trends

• The Phillies have been chosen as favorites in 26 games this year and have walked away with the win 14 times (53.8%) in those games.
• This year, the Phillies have won six of eight games when listed as at least -166 or better on the moneyline.
• The Phillies and their opponents have hit the over in 18 of their 36 games with a total this season.
• The Phillies have posted a record of 8-28-0 against the spread this season.
• The Athletics have gone 13-13 in games they were the underdog on the moneyline (winning 50% of those games).
• In games they have played as a moneyline underdog with odds of +140 or longer, the Athletics have gone 3-6 (33.3%).
• The Athletics have combined with their opponents to hit the over on the total 17 times this season for a 17-18-0 record against the over/under.
• The Athletics have gone 20-15-0 ATS this season.

Phillies Player Leaders

• Bryce Harper has 38 hits and an OBP of .377 to go with a slugging percentage of .571. All three of those stats rank first among Philadelphia hitters this season. He has a .286 batting average, as well.
• Among the qualified hitters in the majors, his batting average ranks 39th, his on-base percentage ranks 34th, and he is 11th in slugging.
• Harper hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .421 with three doubles, three home runs, three walks and four RBIs.
• Kyle Schwarber is batting .205 with six doubles, a triple, 11 home runs and 25 walks, while slugging .515 with an on-base percentage of .348.
• Among all qualifying players, he ranks 158th in batting average, 68th in on-base percentage and 26th in slugging percentage.
• Brandon Marsh has 37 hits this season and has a slash line of .322/.350/.487.
• Marsh heads into this game with seven games in a row with at least one hit. In his last 10 games he is hitting .371 with three doubles, a walk and four RBIs.
• Trea Turner has four home runs, 12 RBI and a batting average of .241 this season.

Athletics Player Leaders

• Jacob Wilson is hitting .296 with eight doubles, two home runs and four walks. He's slugging .394 with an on-base percentage of .313.
• Including all qualifying hitters, he is 32nd in batting average, while his on-base percentage is 113th and he is 99th in slugging.
• Wilson heads into this game on a nine-game hitting streak. During his last 10 outings he is hitting .342 with three doubles, three walks and two RBIs.
• Tyler Soderstrom has 11 doubles, a triple, four home runs and 16 walks while hitting .216. He's slugging .416 with an on-base percentage of .303.
• He is currently 139th in batting average, 131st in on-base percentage and 76th in slugging percentage among all qualifying batters.
• Carlos Cortes is hitting .387 with five doubles, a triple, four home runs and eight walks.
• Nick Kurtz leads his team with a .408 OBP.

Phillies vs Athletics Head to Head

• 5/5/2026: 9-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/25/2025: 5-4 OAK (Favorite: Phillies, Spread: -1.5, Total: 10, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 5/24/2025: 9-6 PHI (Favorite: Phillies, Spread: -1.5, Total: 10, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/23/2025: 4-3 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/14/2024: 18-3 OAK (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 7/13/2024: 11-5 PHI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 7/12/2024: 6-2 OAK (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 6/18/2023: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 7.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/17/2023: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/16/2023: 6-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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