Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 7:14 a.m.

In MLB action on Saturday, the Detroit Tigers face the Cleveland Guardians.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Guardians Game Info

• Detroit Tigers (33-19) vs. Cleveland Guardians (28-22)
• Date: Saturday, May 24, 2025
• Time: 7:15 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: FOX

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-146) | CLE: (+124)
• Spread: DET: -1.5 (+140) | CLE: +1.5 (-170)
• Total: 8 -- Over: (-115) | Under: (-105)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Casey Mize (Tigers) - 6-1, 2.53 ERA vs Luis Ortiz (Guardians) - 2-5, 4.66 ERA

The Tigers will give the ball to Casey Mize (6-1, 2.53 ERA), who is eyeing win No. 7 on the season, and the Guardians will counter with Luis Ortiz (2-5, 4.66 ERA). Mize's team is 5-2-0 against the spread in his starts this season. Mize has started four games with his team as the moneyline favorite and won each of them. The Guardians are 3-6-0 against the spread when Ortiz starts. The Guardians have a 1-4 record in Ortiz's five starts this season when they were the underdog on the moneyline.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (58.2%)

Tigers vs Guardians Moneyline

• Detroit is a -146 favorite on the moneyline, while Cleveland is a +124 underdog on the road.

Tigers vs Guardians Spread

• The Guardians are +1.5 on the spread (-170 to cover), and Detroit is +140 to cover the runline.

Tigers vs Guardians Over/Under

• Tigers versus Guardians on May 24 has an over/under of 8 runs, with the odds on the over -115 and the under set at -105.

Bet on Detroit Tigers vs. Cleveland Guardians on FanDuel today!

Tigers vs Guardians Betting Trends

• The Tigers have won in 21, or 70%, of the 30 contests they have been named as odds-on favorites in this year.
• Detroit has a record of 16-2 in contests when bookmakers favor them by -146 or more on the moneyline.
• The Tigers' games have gone over the total in 25 of their 51 opportunities.
• The Tigers are 27-24-0 against the spread in their 51 games that had a posted line this season.
• The Guardians have won 51.7% of the games this season they were the underdog on the moneyline (15-14).
• Cleveland has a 4-5 record (winning 44.4% of its games) when it has played as a moneyline underdog of +124 or longer.
• In the 48 games bookmakers have set an over/under for the Guardians, they have combined with opponents to go over the total 22 times (22-24-2).
• The Guardians have a 23-25-0 record against the spread this season (covering 47.9% of the time).

Tigers Player Leaders

• Spencer Torkelson leads Detroit in total hits (44) this season while batting .244 with 26 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .533.
• Among all qualifying batters, he ranks 101st in batting average, his on-base percentage ranks 53rd, and he is 18th in slugging.
• Riley Greene has hit 12 homers this season while driving in 34 runs. He's batting .280 this season and slugging .518 with an on-base percentage of .335.
• Among qualifying hitters, his batting average ranks him 41st, his on-base percentage 73rd, and his slugging percentage 25th.
• Gleyber Torres has collected 39 base hits, an OBP of .355 and a slugging percentage of .417 this season.
• Kerry Carpenter is batting .280 with a .314 OBP and 22 RBI for Detroit this season.
• Carpenter enters this game on a two-game hitting streak. During his last five outings he is hitting .176 with a double, a home run, two walks and an RBI.

Guardians Player Leaders

• Jose Ramirez has 55 hits, a team-best for the Guardians. He's batting .306 and slugging .522 with an on-base percentage of .365.
• Including all qualifying hitters in the majors, his batting average puts him 14th, his on-base percentage is 37th, and he is 23rd in slugging.
• Ramirez hopes to build on a 16-game hitting streak in this matchup. During his last 10 games he is batting .375 with two doubles, a triple, three home runs, four walks and seven RBIs.
• Steven Kwan leads his team with a .378 on-base percentage, and has a club-best .442 slugging percentage. He has a batting average of .322.
• Including all qualified players, he ranks sixth in batting average, 25th in on-base percentage and 63rd in slugging percentage.
• Carlos Santana is hitting .235 with four doubles, six home runs and 26 walks.
• Kyle Manzardo is batting .214 with five doubles, two triples, 10 home runs and 21 walks.

Tigers vs Guardians Head to Head

• 5/23/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/22/2025: 7-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/12/2024: 7-3 CLE (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/10/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/9/2024: 3-0 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/7/2024: 3-0 DET (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 10/5/2024: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/30/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/29/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/25/2024: 3-0 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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