Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 7:11 p.m.

MLB action on Saturday includes the Detroit Tigers taking on the Cleveland Guardians.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Tigers vs Guardians Game Info

• Detroit Tigers (33-19) vs. Cleveland Guardians (28-22)
• Date: Saturday, May 24, 2025
• Time: 7:15 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: FOX

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-142) | CLE: (+120)
• Spread: DET: -1.5 (+140) | CLE: +1.5 (-170)
• Total: 8.5 -- Over: (-112) | Under: (-108)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Casey Mize (Tigers) - 6-1, 2.53 ERA vs Luis Ortiz (Guardians) - 2-5, 4.66 ERA

This contest's pitching matchup is set, as the Tigers will send Casey Mize (6-1) to the mound, while Luis Ortiz (2-5) will take the ball for the Guardians. Mize's team is 5-2-0 against the spread this season in his starts. Mize and his team have won each of the four games he's started as the moneyline favorite. The Guardians have gone 3-6-0 ATS in Ortiz's nine starts that had a set spread. The Guardians have been the underdog on the moneyline in five of Ortiz's starts this season, and they went 1-4 in those games.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (58.5%)

Tigers vs Guardians Moneyline

• The Tigers vs Guardians moneyline has Detroit as a -142 favorite, while Cleveland is a +120 underdog on the road.

Tigers vs Guardians Spread

• The Tigers are 1.5-run home favorites on the runline against the Guardians. The Tigers are +140 to cover, and the Guardians are -170.

Tigers vs Guardians Over/Under

• Tigers versus Guardians on May 24 has an over/under of 8.5 runs, with the odds on the over -112 and the under set at -108.

Bet on Detroit Tigers vs. Cleveland Guardians on FanDuel today!

Tigers vs Guardians Betting Trends

• The Tigers have been favorites in 30 games this season and have come away with the win 21 times (70%) in those contests.
• Detroit has a record of 18-2 when favored by -142 or more this year.
• The Tigers and their opponents have gone over in 25 of their 51 games with a total set by sportsbooks this season.
• The Tigers are 27-24-0 against the spread in their 51 games with a line set by sportsbooks this season.
• The Guardians are 15-14 in games they were the underdog on the moneyline (winning 51.7% of those games).
• In games it has played as a moneyline underdog with odds of +120 or longer, Cleveland has a record of 4-5 (44.4%).
• The Guardians have played in 48 games with a set over/under, and have combined with their opponents to go over the total 22 times (22-24-2).
• The Guardians have covered 47.9% of their games this season, going 23-25-0 against the spread.

Tigers Player Leaders

• Spencer Torkelson leads Detroit in total hits (44) this season while batting .244 with 26 extra-base hits. He has an on-base percentage of .353 and a slugging percentage of .533.
• Among all qualified batters in the majors, he ranks 100th in batting average, 48th in on-base percentage, and 17th in slugging.
• Riley Greene leads Detroit in slugging percentage (.518) thanks to 22 extra-base hits. He's batting .280 with an on-base percentage of .335.
• Among qualifying batters, his batting average places him 39th, his on-base percentage 71st, and his slugging percentage 24th.
• Gleyber Torres has 39 hits this season and has a slash line of .271/.355/.417.
• Kerry Carpenter is batting .280 with a .314 OBP and 22 RBI for Detroit this season.
• Carpenter heads into this game on a two-game hitting streak. In his last five games he is hitting .176 with a double, a home run, two walks and an RBI.

Guardians Player Leaders

• Jose Ramirez is leading the Guardians with 55 hits. He's batting .306 and slugging .522 with an on-base percentage of .365.
• Including all qualifying hitters in the big leagues, his batting average puts him 15th, his on-base percentage is 35th, and he is 22nd in slugging.
• Ramirez hopes to build on a 16-game hitting streak in this matchup. During his last 10 outings he is batting .375 with two doubles, a triple, three home runs, four walks and seven RBIs.
• Steven Kwan's .378 on-base percentage and .442 slugging percentage both lead his team. He has a batting average of .322.
• Including all qualifying hitters, he is sixth in batting average, 25th in on-base percentage and 63rd in slugging percentage.
• Carlos Santana has four doubles, six home runs and 26 walks while batting .235.
• Kyle Manzardo is batting .214 with five doubles, two triples, 10 home runs and 21 walks.

Tigers vs Guardians Head to Head

• 5/23/2025: 3-1 CLE (Favorite: Tigers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/22/2025: 7-0 CLE (Favorite: Tigers, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/12/2024: 7-3 CLE (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/10/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 10/9/2024: 3-0 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/7/2024: 3-0 DET (Favorite: Tigers, Spread: -1.5, Total: 6, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 10/5/2024: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/30/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 7/29/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/25/2024: 3-0 DET (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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