Tigers vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for May 18

Odds updated as of 6:11 p.m.

The Detroit Tigers will face the Cleveland Guardians in MLB action on Monday.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Tigers vs Guardians Game Info

• Detroit Tigers (20-27) vs. Cleveland Guardians (26-22)
• Date: Monday, May 18, 2026
• Time: 6:40 p.m. ET
• Venue: Comerica Park -- Detroit, Michigan
• Coverage: Fox Sports 1, DSN, and CleGuardians.TV

Tigers vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-146) | CLE: (+124)
• Spread: DET: -1.5 (+136) | CLE: +1.5 (-164)
• Total: 8 -- Over: (-115) | Under: (-105)

Tigers vs Guardians Probable Starting Pitchers

Probable Pitchers: Framber Valdez (Tigers) - 2-2, 4.32 ERA vs Slade Cecconi (Guardians) - 2-4, 5.60 ERA

This contest's pitching matchup is set, as the Tigers will send Framber Valdez (2-2) to the mound, while Slade Cecconi (2-4) will get the nod for the Guardians. Valdez and his team are 5-4-0 ATS this season when he starts. Valdez's team has a record of 2-3 this season when he starts and they are the favorite on the moneyline. The Guardians have gone 3-6-0 against the spread when Cecconi starts. The Guardians have a 2-5 record in Cecconi's seven starts this season when they were the underdog on the moneyline.

Tigers vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Tigers win (64.1%)

Tigers vs Guardians Moneyline

• Cleveland is the underdog, +124 on the moneyline, while Detroit is a -146 favorite at home.

Tigers vs Guardians Spread

• The Tigers are hosting the Guardians and are favored by 1.5 runs (+136 to cover) on the runline. Cleveland is -164 to cover.

Tigers vs Guardians Over/Under

• An over/under of 8 has been set for Tigers-Guardians on May 18, with the over being -115 and the under -105.

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Tigers vs Guardians Betting Trends

• The Tigers have won in 13, or 52%, of the 25 contests they have been named as odds-on favorites in this year.
• Detroit has a record of 5-4 in contests when bookmakers favor them by -146 or more on the moneyline.
• The Tigers and their opponents have hit the over in 21 of their 47 games with a total set by oddsmakers this season.
• The Tigers are 23-24-0 against the spread in their 47 games that had a posted line this season.
• The Guardians have an 11-10 record in games they were listed as the moneyline underdog (winning 52.4% of those games).
• In games it has played as a moneyline underdog with odds of +124 or longer, Cleveland has a 4-4 record (winning 50% of its games).
• The Guardians have played in 46 games with an over/under set, and have combined with opponents to go over the total 25 times (25-21-0).
• The Guardians have collected a 25-21-0 record ATS this season (covering 54.3% of the time).

Tigers Player Leaders

• Kevin McGonigle is hitting .290 with 12 doubles, two triples, two home runs and 27 walks. He has an on-base percentage of .394 and a slugging percentage of .420.
• Among the qualified hitters in the majors, his batting average ranks 28th, his on-base percentage ranks 13th, and he is 72nd in slugging.
• McGonigle will look for his third straight game with a hit in this contest. In his last five games he is hitting .211 with three walks.
• Riley Greene has a slash line of .320/.410/.473 this season and a team-best OPS of .884.
• Among qualified hitters, his batting average ranks him seventh, his on-base percentage fourth, and his slugging percentage 40th.
• Dillon Dingler leads Detroit with 37 hits. He is batting .252 this season and 17 of his hits have gone for extra bases.
• Matt Vierling is batting .207 with a .280 OBP and 18 RBI for Detroit this season.

Guardians Player Leaders

• Jose Ramirez has nine doubles, seven home runs and 35 walks while hitting .229. He's slugging .400 with an on-base percentage of .358.
• Including all the qualifying players in MLB, his batting average ranks 128th, his on-base percentage ranks 46th, and he is 87th in slugging.
• Ramirez hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .353 with a double, a home run, four walks and three RBIs.
• Chase DeLauter leads his team with a .367 on-base percentage, and has a club-leading .494 slugging percentage. He has a batting average of .282.
• His batting average is 35th among all qualified players, his on-base percentage is 39th, and he is 29th in slugging.
• Brayan Rocchio is hitting .285 with five doubles, four home runs and 16 walks.
• Angel Martinez's 38 hits pace his team.

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