Spurs vs. Pacers Prediction, Odds, Picks, Best Bets for March 21

Spurs vs. Pacers Game Info

• Date: Saturday, March 21, 2026
• Time: 8 p.m. ET
• Venue: Frost Bank Center -- San Antonio, Texas
• Coverage: FDSIN and FDSSW

The Indiana Pacers (15-55) are big, 17-point underdogs as they try to stop a 15-game losing streak when they visit the San Antonio Spurs (52-18) on Saturday, March 21, 2026 at Frost Bank Center. The contest airs at 8 p.m. ET on FDSIN and FDSSW. The matchup has an over/under set at 233.5 points.

Spurs vs. Pacers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Spurs vs. Pacers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Spurs win (89%)

Spurs vs. Pacers Betting Trends

• The Spurs are 36-29-4 against the spread this season.
• The Pacers have played 70 games, with 30 wins against the spread.
• This season, 30 of the Spurs' games have gone over the point total.
• Pacers games this year have hit the over on 34 of 70 set point totals (48.6%).
• San Antonio has covered the spread in a lower percentage of its home games than away games. It has covered 16 times in 34 games when playing at home, and it has covered 20 times in 36 games when playing on the road.
• In home games, the Spurs eclipse the over/under 44.1% of the time (15 of 34 games). They've hit the over in 41.7% of road games (15 of 36 contests).
• This year, Indiana is 19-16-0 at home against the spread (.543 winning percentage). Away, it is 11-24-0 ATS (.314).
• In terms of the over/under, Pacers games have gone over more often at home (18 of 35, 51.4%) than away (16 of 35, 45.7%).

Spurs Leaders

• Victor Wembanyama averages 24.3 points, 11.1 rebounds and 2.9 assists.
• De'Aaron Fox's numbers on the season are 19 points, 3.8 boards and 6.2 assists per game, shooting 48.9% from the floor and 34.2% from downtown, with an average of 1.9 made treys.
• Stephon Castle averages 16.4 points, 5 boards and 7.1 assists, shooting 46.4% from the floor and 31.4% from beyond the arc, with 1.1 made treys per contest.
• Julian Champagnie averages 11.2 points, 5.7 boards and 1.5 assists, shooting 43.7% from the field and 38.9% from beyond the arc, with 2.5 made treys per game.
• Keldon Johnson's numbers on the season are 12.7 points, 5.4 rebounds and 1.3 assists per game, shooting 52.8% from the field and 37.4% from beyond the arc, with an average of 1.2 made 3-pointers.

Pacers Leaders

• Pascal Siakam averages 24 points for the Pacers, plus 6.7 boards and 3.9 assists.
• Andrew Nembhard averages 17 points, 2.8 rebounds and 7.3 assists. He is also sinking 44% of his shots from the floor and 36.3% from beyond the arc, with 1.9 treys per contest.
• Jarace Walker's numbers on the season are 11.3 points, 5.2 rebounds and 2.4 assists per game. He is sinking 41% of his shots from the field and 36.3% from 3-point range, with an average of 1.7 triples.
• The Pacers receive 9.4 points per game from Jay Huff, plus 3.8 boards and 1.3 assists.
• T.J. McConnell averages 9.3 points, 2.3 rebounds and 5.1 assists. He is making 52.5% of his shots from the floor.

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