Royals vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 5

Odds updated as of 7:16 p.m.

The Kansas City Royals will take on the Minnesota Twins in MLB action on Friday.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Royals vs Twins Game Info

• Kansas City Royals (71-69) vs. Minnesota Twins (62-78)
• Date: Friday, September 5, 2025
• Time: 7:40 p.m. ET
• Venue: Kauffman Stadium -- Kansas City, Missouri
• Coverage: FDSKC and MNNT

Royals vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: KC: (-132) | MIN: (+112)
• Spread: KC: -1.5 (+146) | MIN: +1.5 (-176)
• Total: 8 -- Over: (-115) | Under: (-105)

Royals vs Twins Probable Starting Pitchers

Probable Pitchers: Michael Wacha (Royals) - 8-11, 3.52 ERA vs Pablo Lopez (Twins) - 5-3, 2.82 ERA

The probable pitchers are Michael Wacha (8-11) for the Royals and Pablo Lopez (5-3) for the Twins. Wacha's team is 12-15-0 against the spread this season in his starts. Wacha's team has won 50% of his starts when they are favored on the moneyline (5-5). When Lopez starts, the Twins are 7-4-0 against the spread. The Twins were the moneyline underdog for two Lopez starts this season -- they lost both.

Royals vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (50%)

Royals vs Twins Moneyline

• Kansas City is the favorite, -132 on the moneyline, while Minnesota is a +112 underdog on the road.

Royals vs Twins Spread

• The Twins are +1.5 on the spread (-176 to cover), and Kansas City is +146 to cover the runline.

Royals vs Twins Over/Under

• The over/under for Royals-Twins on Sept. 5 is 8. The over is -115, and the under is -105.

Bet on Kansas City Royals vs. Minnesota Twins on FanDuel today!

Royals vs Twins Betting Trends

• The Royals have been victorious in 34, or 56.7%, of the 60 contests they have been chosen as favorites in this season.
• Kansas City has a record of 20-17 in contests when oddsmakers favor them by -132 or more on the moneyline.
• The Royals and their opponents have gone over the total this season in 58 of their 138 opportunities.
• The Royals are 69-69-0 against the spread in their 138 games that had a posted line this season.
• The Twins have compiled a 19-32 record in games they were the underdog on the moneyline (winning 37.3% of those games).
• Minnesota is 9-16 (winning only 36% of its games) when it has played as a moneyline underdog of +112 or longer.
• In the 135 games bookmakers have set an over/under for the Twins, they have combined with opponents to go over the total 64 times (64-64-7).
• The Twins are 65-70-0 ATS this season.

Royals Player Leaders

• Bobby Witt Jr. has 160 hits to go with a slugging percentage of .506, both of which are best among Kansas City hitters this season. He has a .295 batting average and an on-base percentage of .354.
• He ranks 10th in batting average, 34th in on-base percentage, and 17th in slugging among qualifying hitters in MLB.
• Maikel Garcia has 150 hits this season and a team-best OBP of .356. He's batting .292 and slugging .466.
• He is 13th in batting average, 29th in on-base percentage and 48th in slugging in the major leagues.
• Vinnie Pasquantino is batting .258 with a .467 slugging percentage and 96 RBI this year.
• Salvador Perez has 24 home runs, 78 RBI and a batting average of .240 this season.
• Perez heads into this game on a two-game hitting streak. In his last five games he is hitting .118 with a double, a home run and an RBI.

Twins Player Leaders

• Byron Buxton has 112 hits, a team-best for the Twins. He's batting .273 and slugging .559 with an on-base percentage of .333.
• Including all qualifying players, he ranks 38th in batting average, while his on-base percentage is 70th and he is fifth in slugging.
• Buxton heads into this game on a seven-game hitting streak. During his last 10 games he is batting .282 with three doubles, two triples, four home runs, three walks and 10 RBIs.
• Trevor Larnach paces his team with a .415 slugging percentage. He has a batting average of .258 with an on-base percentage of .330.
• Including all qualified hitters, he is 83rd in batting average, 79th in on-base percentage and 90th in slugging percentage.
• Brooks Lee is batting .242 with 13 doubles, a triple, 14 home runs and 26 walks.
• Ryan Jeffers' .353 on-base percentage leads his team.

Royals vs Twins Head to Head

• 8/10/2025: 5-3 MIN (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/9/2025: 2-0 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/8/2025: 9-4 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/25/2025: 2-1 KC (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/24/2025: 5-4 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/23/2025: 3-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 4/10/2025: 3-2 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/9/2025: 4-0 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/8/2025: 2-1 KC (Favorite: Royals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/7/2025: 4-2 KC (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)

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