Rice vs Charlotte Prediction, Odds, Picks, Best Bets for Week 4 2025

The Rice Owls versus the Charlotte 49ers is on the college football schedule for Thursday.

We've got you covered, in terms of the vital information about NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Rice vs Charlotte Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Rice: (-140) | Charlotte: (+116)
• Spread: Rice: -2.5 (-115) | Charlotte: +2.5 (-105)
• Total: 42.5 -- Over: (-110) | Under: (-110)

Rice vs Charlotte Betting Trends

• Rice has one win against the spread this season.
• Rice is winless ATS (0-1) as a 2.5-point favorite or greater this year.
• Rice has had two games (out of three) go over the total this year.
• Charlotte has posted one win against the spread this year.
• Charlotte has no wins ATS (0-2) as a 2.5-point underdog or greater this season.
• One of Charlotte's three games has gone over the point total.

Rice vs Charlotte Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Owls win (58.9%)

Rice vs Charlotte Point Spread

Charlotte is a 2.5-point underdog against Rice. Charlotte is -105 to cover the spread, and Rice is -115.

Rice vs Charlotte Over/Under

A combined point total of 42.5 has been set for Rice-Charlotte on Sept. 18, with the over at -110 and the under at -110.

Rice vs Charlotte Moneyline

Looking at the moneyline for Rice-Charlotte, Rice is the favorite at -140, and Charlotte is +116.

Rice vs. Charlotte Points Insights

Rice vs. Charlotte Game Info

• Game day: Thursday, September 18, 2025
• Game time: 7:30 p.m. ET
• TV channel: ESPN
• Location: Charlotte, North Carolina
• Stadium: Jerry Richardson Stadium

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Check out even more in-depth Rice vs. Charlotte analysis on FanDuel Research.